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Microfabrication methods are an emerging technology which enables to build micro scale airborne particle mass concentration measurement systems. A personal airborne particle monitoring system can be achieved by combining an appropriate sampling method with inertial micro-electromechanical systems (MEMS) mass sensors. While aerosol sampling methods can take airborne particles from ambient air and transport to a detector in the most efficient way, MEMS provide the detection and estimation of the mass based on a shift in the resonance frequency of oscillating sensors.In this context, an extensive literature review is proposed in order to examine the mass concentration measurement methods from past to present. The methodological tendencies for advanced real-time aerosol mass concentration measurement are evaluated. Finally, bulk-mode silicon-based MEMS mass sensor is chosen to be coupled with an appropriate aerosol sampler.Following that the miniaturization possibilities of aerosol sampling methods are discussed and inertial impactor is chosen as a suitable aerosol sampling method. Then, the impactor is designed, fabricated, and characterized based on the classical impaction theory. The latter, the deposition characteristics of monodisperse aerosol (fluorescent) and bioaerosols (Aspergillus niger, Staphylococcus epidermidis, Pseudomonas fluorescens) are explored by inertial impaction on silicon and nanostructured silicon (i.e. black silicon). The empirical results show that the size of airborne particles plays a key role to determine the deposition characteristics of the impaction by the mechanism of rebound and re-entrainment (i.e. bounce effect) of the particles.In the context of developing an inertial mass sensor, sub-μm air gap MEMS mass sensors have been successfully fabricated based on the thick oxide as a mask layer method. This method enables to fabricate high-aspect-ratio air-gap MEMS resonators. Then, the devices are electrically characterized and the mass resolution is investigated. As a result, high-aspect-ratio MEMS sensors are operated in two different bulk modes (Lamé and extensional modes) and the mass resolution of the sensors is found to be as sub-ng.Finally, the fabricated MEMS mass sensors are integrated into the developed impactor and monodisperse fluorescent particles are successively impacted on the sensors. The shift in the resonance frequency of MEMS mass sensors are evaluated based on Sauerbrey's principle. Ultimately, MEMS mass sensors have achieved to detect and perform mass measurements of the impacted fluorescent particles with a promising precision. Although more impactions are needed to calibrate the sensors, the theoretical mass sensitivity of the device is matched with the experimental mass sensitivity obtained from successive impactions. Therefore, the developed airborne particle detection system paves the way for real-time detection and mass measurements of aerosol and bioaerosols.
This book is intended to give technological background and practical examples, but also to give general insight into the on-going technology development in the area of biodetection. The content is therefore suitable for an array of stakeholders (decision makers, purchasing officers, etc.) and end-users of biodetection equipment within the areas of health, environment, safety and security, and military preparation. The book is divided into three sections. The first section discusses the fundamental physical and biological properties of bioaerosol's. The second section goes into more detail and discusses in-depth the most commonly used detection principles. The third section of the book is devoted to technologies that have been used in standoff applications. The last section of the book gives an overview of trends in bioaerosol detection. The reader of this book will gain knowledge about the different biodetection technologies and thus better judge their capabilities in relation to desired applications.
Nanoscience and nanotechnologies are leading to a major point to our understanding of nature. Nanotechnology can be generally defined as creation and use of nano-sized systems, devices, and structures which have special functions or properties because of their small size. This volume on Nanotechnology Applications in Health and Environmental Sciences focuses on biotechnological and environmental applications of nanomaterials. It covers popular and various nanomedical topics such as oncology, genetics, and reconstructive medicine. Additionally, many chapters give leading-edge information on nano-sensor applications and usage in specific disciplines. Also, two chapters on novel subjects have been included on Lantibiotics and microbiota. This book should be useful for nanotechnologists, microbiologists, and researchers interested in nanomedicine and nano-biotechnology, as well as environmental nanotechnology.
Surface Acoustic Wave Devices and Their Signal Processing Applications is a textbook that combines experiment and theory in assessing the signal processing applications of surface acoustic wave (SAW) devices. The operating principles of SAW devices are described from a circuit design viewpoint. This book is comprised of 18 chapters and begins with a historical background on surface acoustic waves and a discussion on the merits of SAW devices as well as their applications. The next chapter introduces the reader to the basics of acoustic waves and piezoelectricity, together with the effect of acoustic bulk waves on the performance of SAW filters. The principles of linear phase SAW filter design and equivalent circuit models for a SAW filter are then described. The remaining chapters focus on trade-offs in linear phase SAW filter design; compensation for second-order effects; harmonic SAW delay lines for gigahertz frequencies; and coding techniques using linear SAW transducers. The final chapter highlights Some other significant alternative design techniques and applications for SAW devices. This monograph will be suitable for engineering or physics students as well as engineers, scientists, and technical staff in industry who seek further information on SAW-based circuits, systems, and applications.
Biosensors are portable and convenient devices that permit the rapid and reliable analysis of substances. They are increasingly used in healthcare, drug design, environmental monitoring and the detection of biological, chemical, and toxic agents. Fractal Binding and Dissociation Kinetics for Different Biosensor Applications focuses on two areas of expanding biosensor development that include (a) the detection of biological and chemical pathogens in the atmosphere, and (b) biomedical applications, especially in healthcare. The author provides numerous examples of practical uses, particularly biomedical applications and the detection of biological or chemical pathogens. This book also contains valuable information dedicated to the economics of biosensors. After reading this book, the reader will gain invaluable insight into how biosensors work and how they may be used more effectively. * No other book provides a detailed kinetic analysis of the binding and dissociation reactions occurring on the biosensor surfaces * Packed with examples of practical uses of biosensors * Includes chapters dedicated to the economics of biosensors
In order to achieve the revolutionary new defense capabilities offered by materials science and engineering, innovative management to reduce the risks associated with translating research results will be needed along with the R&D. While payoff is expected to be high from the promising areas of materials research, many of the benefits are likely to be evolutionary. Nevertheless, failure to invest in more speculative areas of research could lead to undesired technological surprises. Basic research in physics, chemistry, biology, and materials science will provide the seeds for potentially revolutionary technologies later in the 21st century.
The “Eddy Covariance Method for Scientific, Industrial, Agricultural and Regulatory Applications: A Field Book on Measuring Ecosystem Gas Exchange and Areal Emission Rates†book has been created to familiarize the reader with the general theoretical principles, requirements, applications, and planning and processing steps of the eddy covariance method. It is intended to assist readers in furthering their understanding of the method, and provide references such as micrometeorology textbooks, networking guidelines and journal papers. In particular, it is designed to help scientific, industrial, agricultural, and regulatory research projects and monitoring programs with field deployment of the eddy covariance method in applications beyond micrometeorology.Some of the topics covered in “Eddy Covariance Method for Scientific, Industrial, Agricultural and Regulatory Applications†include:Overview of eddy covariance principlesPlanning and design of an eddy covariance experiment Implementation of an eddy covariance experiment Processing eddy covariance dataAlternative flux methodsUseful resources, training and knowledge baseExample of planning, design and implementation of a complete eddy covariance station
This book covers the full scope of biochemical sensors and offers a survey of the principles, design and applications of the most popular types of biosensing devices. It is presented in 19 chapters, written by 20 distinguished scientists as well as their co-workers. The topics include the design of signal transducers, signal tags and signal amplification strategies, the structure of biosensing interfaces with new biorecognition elements such as aptamers and DNAzymes, and different newly emerging nanomaterials such as Au nanoclusters, carbon nitride, silicon, upconversion nanoparticles and two-dimensional materials, and the applications in wearable detections, biofuel cells, biomarker analyses, bioimaging, single cell analysis and in vivo sensing.By discussing recent advances, it is hoped this book will bridge the common gap between research literature and standard textbooks. Research into biochemical sensors and their biomedical applications is proceeding in a number of exciting directions, as reflected by the content. This book is published in honor of the 90th birthday of Professor Shaojun Dong, who performed many pioneering studies on modified electrodes and biochemical sensors.