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Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
Support your immunity and fuel your metabolism with this revolutionary guide to gut health, including 50 fiber-packed recipes to nourish your microbiome—from the award-winning Gut Health Doctor (@TheGutHealthDoctor) and author of the forthcoming How to Eat More Plants Publisher’s Note: Love Your Gut was previously published in the UK under the title Eat Yourself Healthy. The path to health and happiness is inside you—literally. It’s your gut! When you eat well, you feed the helpful gut microbes that nourish your metabolism, your immunity, and even your mood. But your microbiome is as unique as you are, so how to eat well varies from person to person. There’s more to it than one-size-fits-all advice like “Take probiotics” and “Eat more fermented foods”—in Love Your Gut, Dr. Megan Rossi cuts through the noise. You’ll learn what your gut actually needs, how it works, and, most importantly, what to do when it’s not loving you back. Gauge your gut health with 11 interactive questionnaires: How happy is your microbiome? Could you have a hidden food intolerance? Are your fruit and veggie choices stuck in a rut? You’ll answer these questions and many more! Craft a personal action plan and treat common problems: Learn to manage IBS, bloating, constipation, heartburn, SIBO, and stress—with evidence-based diet strategies, gut-directed yoga flows, sleep hygiene protocols, bowel massage techniques, and more. Enjoy 50 plant-forward, fiber-filled recipes, including Banana, Fig, and Zucchini Breakfast Loaf, Sautéed Brussels Sprouts and Broccolini with Pesto and Wild Rice, Prebiotic Chocolate Bark, and more! Get ready to discover your happiest, healthiest self. Love your gut!
The unique and powerful Gut Reset diet plan for sufferers of IBS and digestive disorders that works to restore healthy gut function in 21 days. After years of severe struggles with IBS and gut dysfunction and finding no relief from the conventional methods of treating IBS (following a low-FODMAP diet, taking medications, managing stress), Bethany Ugarte took matters into her own hands. She changed her diet with the help of a holistic doctor, eliminating all gut irritants and eating nutrient-dense, easily digested foods like Greek yogurt, bone broth, collagen, and pureed protein for maximum nutrient absorption. Her painful, debilitating symptoms disappeared. Now she's synthesized her hard-won wisdom into a 21-day Gut Reset protocol and maintenance plan that works to "heal and seal" your gut, restoring digestive health. Her Gut Reset program includes powerful techniques that help to ensure maximum absorption from foods, cutting out little-known irritants and integrating foods that your gut needs to heal. She offers meal plans, stress reduction techniques, and creative recipes that deliver maximum flavor and nutrients with minimal ingredients. Recipes include Cookie Dough Milkshake, Blueberry Protein Scones, Carrot Bacon and Eggs, Chili-Stuffed Spaghetti Squash Pasta, Paleo Spinach Dip, Pecan Pie Bread, and Sea Salt Butternut Fudge. No matter how severe your symptoms may be, Digest This will help you eat without stress or fear in just 21 days.
Accompanying CD-ROM contains: contents of book; continuous updates; slide image library; references linked to MEDLINE; pediatric guidelines; case studies; review questions.
Packed with easy-to-follow advice, the latest science and accessible and nourishing recipes and meal plans, nutritionist Jeannette Hyde's radical new approach will help you: · Lose weight with a tried and tested four week plan · Transform the look of your skin and hair · Address any long-standing digestive problems including bloating and IBS · Strengthen your immune system · Experience fewer mood swings and less anxiety · Sleep better · Eat for a healthy mind and body with over 50 delicious recipes The Gut Makeover is based on revolutionary new science that reveals that the state of our gut is central to our weight and health. Learn how to rebuild your microbiome – the bacteria living in the human gut – which is the key to every single aspect of our health. The great news is there is a lot you can do to cultivate a healthy gut. The Gut Makeover is the only book you'll need for a whole health overhaul – to control your weight, improve your skin, lift your spirits and strengthen your immune system for good. This is more than another fad diet. This is a lifestyle you'll want to adopt for life.
A renowned physician shares her complete 10-day digestive tune-up for women, with important revelations about good gastrointestinal health. Many so-called cures for women’s bloating and indigestion, from juice cleanses to specialty diets, are based on junk science. For women seeking true relief from that overall feeling of discomfort in any size jeans, Dr. Robynne Chutkan has the perfect plan for feeling light, tight, and bright in ten days. Gutbliss offers: A primer on the real reasons for gastrointestinal distress, and why it’s much more common in women A look at the debilitating side effects of supposedly healthy habits—from Greek yogurt to bloat-inducing aspirin An expert analysis of symptoms that could indicate a serious underlying condition An indispensable checklist to pinpoint the exact cause of your bloating Just a few small changes in diet, lifestyle, and exercise can make a huge difference in a woman’s digestive health, but the changes have to be the right ones. Going beyond the basics of top sellers such as Wheat Belly, Dr. Chutkan’s Gutbliss empowers women to take control of their gastrointestinal wellness.
America's trusted digestive nutrition expert shares her personal program to vanquish bloating in a groundbreaking book that will help readers see results in a week or less! With 50 recipes from former Bon Appétit editor and cookbook author Kristine Kidd “This book could be a game-changer for anyone suffering from chronic belly upset...a deliciously do-able plan to keep you happy, healthy and bloat-free.” --Ellie Krieger, MS RD, host of Ellie’s Real Good Food, and award-winning cookbook author "With candor and science-based expertise, Freuman offers invaluable information for readers suffering from a range of debilitating digestive issues." -- Publishers Weekly, starred review Bloating: ugh. About the most common complaint they get from patients, according to gastroenterologists. But Tamara Duker Freuman, a highly trained and sought-after nutritionist, knows something many doctors don’t: every unhappy belly is unhappy in its own way. That’s why Tamara’s clients call her “The Bloated Belly Whisperer,” and for good reason—for many years she’s successfully helped her clients accurately describe their symptoms, and find a course of treatment that delivers rapid and lasting relief. In The Bloated Belly Whisperer, Tamara guides readers through the same steps she would use in a consultation, first with a quiz to help them hone in on their specific symptoms, and then by discussing the latest research and patient stories to offer dozens of solutions that will reduce abdominal bloating in a week or less by: · Helping identify the specific cause of bloating · Equipping readers with the right terminology and questions to take to their next doctor’s visit · Teaching the most effective dietary remedies for each particular brand of bloating · Laying out the tools and healthy practices to end abdominal distress and bloating once and for all
Do you feel stuck? So many of us live stuck. Stuck in trying to seem perfect. Stuck in sadness. Stuck feeling numb. Stuck pursuing more stuff to make us happy. Stuck in something we can't even name. These stuck places often go unattended inside of us and they are shaping our lives more than we would like to think. We've been trying to fix this feeling with everything but... God. He has a plan for these spaces inside of us, the places we feel broken, but we have to go to Him. Stuck is a journey to take an honest look at the fight going on inside, leading us to the God who has a plan to restore it, to restore us. The eight lessons in this study guide are simple and interactive, offering projects, stories, and Bible study to dig into Scripture, to deeply engage the mind and heart. Because as we realize that our stuck places are the very places that make us ache for God, we find Him waiting there for us with hope and freedom. Sessions include: stuck broken mad discontent scared overwhelmed sad unstuck Designed for use with the Stuck DVD 9780849922541 (sold separately).