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The term steroid has become virtually synonymous with drug abuse in sport to the majority of the public. However these steroids - androgens - actually comprise only a single relatively small class of biologically active steroids, and are overshadowed by a large collection of compounds, a sizeable number of which are commercial drugs that share the same structural carbon skeleton. The development of these drugs has led to a large body of organic chemistry often denoted as "Steroid Chemistry". Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry. Topics covered include: history, isolation and structure determination of steroids steroid nomenclature and stereochemistry natural sources of steroids synthesis and reactions of aromatic a-ring steroids, androstanes, and pregnanes steroids with a spirolactone at position 17 steroids with hetrocyclic ring A compounds derived from cholesterol Based on the highly successful and student friendly "at a glance" approach, the information is presented in integrated, self contained double page spreads of text and illustrative material. Students of chemistry and pharmacy using Steroid Chemistry at a Glance will find they have a resource with which they can quickly, concisely and confidently acquire, regularly review and revise the basic facts that underpin the properties, synthesis and reactions of this important class of natural products. It will also serve as a handy bench reference for postgraduates and professional chemists.
This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly "at a glance" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted.
The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
Natural products have been a fertile area of chemical investigation for many years, driving the development of both analytical chemistry and of new synthetic reactions and methodologies. Many of the most important synthetic reactions in chemistry have been developed in the quest to characterise and synthesise these materials. Natural Product Chemistry at a Glance provides a concise overview of the main principles and reactions of natural product chemistry, for students studying chemistry and related courses at undergraduate level. Based on the highly successful and student friendly "at a glance" approach, the material developed in this book has been chosen to reinforce the principles of elementary organic reactions and to highlight the similarity between many organic reactions and biological processes. It will also serve as an initial platform for more advanced excursions into the origin of natural products. Students using Natural Product Chemistry at a Glance will find they have a resource with which they can quickly, economically and confidently acquire, regularly review and revise the basic facts that underpin the biosynthesis and chemistry of natural products.
Offering a concise, illustrated summary of biochemistry and its relevance to clinical medicine, Medical Biochemistry at a Glance is intended for students of medicine and the biomedical sciences such as nutrition, biochemistry, sports science, medical laboratory sciences, physiotherapy, pharmacy, physiology, pharmacology, genetics and veterinary science. It also provides a succinct review and reference for medical practitioners and biomedical scientists who need to quickly refresh their knowledge of medical biochemistry. The book is designed as a revision guide for students preparing for examinations and contains topics that have been identified as 'high-yield' facts for the United States Medical Licensing Examination (USMLE), Step 1. This third edition: Has been thoroughly revised and updated and is now in full colour throughout Is written by the author of the hugely successful Metabolism at a Glance (ISBN 9781405107167) Features updated and improved clinical correlates Expands its coverage with a new section on Molecular Biology Includes a brand new companion website of self-assessment questions and answers at www.ataglanceseries.com/medicalbiochemistry
This concise and popular introduction to medical microbiology and infection encapsulates the fundamental facts and principles of this rapidly growing and changing subject area. Written by experienced clinicians and teachers, it covers the basic concepts of medical microbiology, and the main human pathogens and infectious syndromes, in an accessible and lucid format. This fully updated fourth edition is now supported by a companion website at www.ataglanceseries.com/medicalmicrobiology containing extra self-assessment cases, colour slides, further reading, and key point summaries. Medical Microbiology and Infection at a Glance is an invaluable revision aid for medical and allied health students and junior doctors, and is ideal for anyone seeking a comprehensive and concise guide to this subject area.
Oncology at a Glance The market-leading at a Glance series is used world-wide by medical students, residents, junior doctors and health professionals for its concise and clear approach and superb illustrations. Each topic is presented in a double-page spread with clear, easy-to-follow diagrams, supported by succinct explanatory text. Covering the whole medical curriculum, these introductory texts are ideal for teaching, learning and exam preparation, and are useful throughout medical school and beyond. Everything you need to know about Oncology...at a Glance! This brand new title in the market-leading at a Glance series brings together fundamental information on cancer biology and treatment to provide a holistic understanding of oncology. It explores both relevant scientific content and key human issues, including communication and palliative care. Oncology at a Glance: Provides an accessible overview of the scientific foundation of cancer medicine Covers the common cancers as well as key information on presentation and approaches to investigation and management Includes young adult oncology, the multidisciplinary team, clinical trials in oncology, approach to treatment and response assessment, management of nausea, and end-of-life care Was developed with students for students, to ensure it contains exactly what students need to know Oncology at a Glance is an ideal guide for medical students and foundation-year doctors as well as any other healthcare professionals looking to consolidate their knowledge of oncology. All content reviewed by students for students Wiley-Blackwell Medical Education books are designed exactly for their intended audience. All our books are developed in collaboration with students, which means our books are always published with you, the student, in mind. If you would like to be one of our student reviewers, go to www.reviewmedicalbooks.com to find out more.
Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This new edition supplies 75 experiments, expanding the range of topics to 22 m
Ear, Nose and Throat at a Glance The market-leading at a Glance series is used world-wide by medical students, residents, junior doctors and health professionals for its concise and clear approach and superb illustrations. Each topic is presented in a double-page spread with clear, easy-to-follow diagrams, supported by succinct explanatory text. Covering the whole medical curriculum, these introductory texts are ideal for teaching, learning and exam preparation, and are useful throughout medical school and beyond. Everything you need to know about Ear, Nose and Throat... at a Glance! Ear, Nose and Throat at a Glance provides a highly-illustrated, accessible introduction to this practical but complex topic, which is increasingly encountered in every-day outpatient settings, as well as surgical departments. Each double-page spread diagrammatically summarises the basic science relating to each anatomical area, outlines practical guidelines on the examination of patients, and provides an overview of the most common disorders and diseases. This brand new title in the best-selling at a Glance series features high-yield information on all the topics covered at medical school, and includes: Advice on clinical skills, practical examinations and procedures, such as otoscopic examinations, and tuning fork tests Comprehensive illustrations showing anatomy and mechanisms of hearing Assessment, management and treatment of both chronic and acute Conditions ENT trauma and emergencies Multiple Choice Questions (MCQs) and Extended Matching Questions (EMQs) to help test learning Ear, Nose and Throat at a Glance is the ideal companion for anyone about to start the ENT attachment, or ‘special senses’ rotation, and will appeal to medical students and junior doctors, as well as nurses, audiologists and other health professionals.
Medical Genetics at a Glance covers the core scientific principles necessary for an understanding of medical genetics and its clinical applications, while also considering the social implications of genetic disorders. This third edition has been fully updated to include the latest developments in the field, covering the most common genetic anomalies, their diagnosis and management, in clear, concise and revision-friendly sections to complement any health science course. Medical Genetics at a Glance now has a completely revised structure, to make its content even more accessible. Other features include: • Three new chapters on Gene Identification, The Biology of Cancer, and Genomic Approaches to Cancer • A much extended treatment of Biochemical Genetics • A completely revised chapter on The Cell Cycle, explaining principles of biochemistry and genetics which are fundamental to understanding cancer causation • Two new chapters on Cardiac Developmental Pathology • An extended Case Studies section Providing a broad understanding of one of the most rapidly progressing topics in medicine, Medical Genetics at a Glance is perfect for students of medicine, molecular biology, genetics and genetic counselling, and is a previous winner of a BMA Award.