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Standard Methods of Clinical Chemistry, Volume I focuses on the methods used most frequently in the clinical laboratory. This book examines the scientific basis of each method, its scope, as well as its limitations. Organized into 19 chapters, this volume starts with an overview of the scope of the clinical chemist's responsibility, which includes the collection of the specimen for analysis, performance of the test, reporting the results to a responsible party, and interpretation of results to clinicians. This book then explores serum amylase activity, which may be demonstrated under several conditions of temperature, time, and substrate quality. Other chapters explore the significance of blood glucose determinations in the detection of diabetes mellitus and the control of this disease by evaluation of the various dosages of insulin. The final chapter deals with the methods for the estimation of uric acid. Clinical chemists, laboratory workers, and technicians will find this book extremely useful.
Standard Methods of Clinical Chemistry, Volume 7 presents the methods to determine how an automated or radioisotope procedure can be best studied and evaluated. This book deals with subjects on control systems and standardization that are essential for effective operation of any clinical chemistry laboratory. Organized into seven parts encompassing 23 chapters, this volume begins with an overview of the technical aspects of the muramidase assay and its usefulness in the diagnosis of a variety of hematologic and renal disorders. This text then examines the use of olive oil as a substrate for measuring lipase activity. Other chapters consider the increased interest in the relationship of serum lipid fractions to coronary artery disease and the hyperlipoproteinemias. This book discusses as well the manual method for determination of serum iron. The final chapter deals with precipitating antigen–antibody systems used in diverse areas as immunology, microbiology, biochemistry, and forensic medicine. This book is a valuable resource for clinical chemists.
Volume 3 presents a wide variety of approaches to analytical procedures in clinical chemistry. This 20-chapter volume discusses the principles
Standard Methods of Clinical Chemistry, Volume 5 presents a wide variety of approaches to analytical procedures in clinical chemistry. This 24-chapter volume discusses the principles, reagents, procedure, and calibration of various clinical chemistry methods. The first three chapters cover the basic protocols in clinical chemistry laboratories, including collection and preservation of specimens, error sources determination, and the automatic chemical analysis. These topics are followed by surveys on determination of blood ammonia, bilirubin, total and free cholesterol, sweat chloride, glucose, and blood and urine lead. Other chapters examine the analysis of magnesium, methemoglobin, osmolality, pH, phenylalanine, and alkaline and acid phosphatase enzymes. The final chapters focus on the methods of colorimetry and turbidimetry for total protein determination. This book is directed primarily toward clinical chemists.
Standard Methods of Clinical Chemistry, Volume 6 provides information pertinent to the more accurate methods of analysis. This book deals with various subjects, including personnel management, electronics, and data processing systems. Organized into 21 chapters, this volume begins with an overview of the most colorimetric methods for estimating uric acid based on the nonspecific reduction of phosphotungstate by uric acid in an alkaline solution. This text then examines the electrophoretic separation and quantitation of proteins in serum or other body fluids. Other chapters provide a discussion of the control of the major reaction variables needed to meet the recommendations of the International Union of Biochemistry. This book discusses as well the modifications developed to eliminate some of the inaccuracies resulting from incomplete destruction of hydrogen peroxide and instability of the developed chromophore. The final chapter deals with the enzymatic methods for the determination of lactic and pyruvic acids in body fluids and tissues. This book is a valuable resource for clinical chemists.
Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. - Includes enhanced illustration and new and revised color figures - Provides improved self-assessment questions and end-of-chapter assessment questions
This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.Landmark Papers addresses:*The origin of the home pregnancy test available today in every drugstore*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize*The scientists who worked on the US Government's crash program at the start of WWII to find a substitute for the malaria drug quinine*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control*First book of this kind dedicated to clinical chemistry*Thirty-nine articles that have shaped the field today*A survey of the major developments in the field clinical chemistry in the 20th century
Gain a clear understanding of pathophysiology and lab testing! Clinical Chemistry: Fundamentals and Laboratory Techniques prepares you for success as a medical lab technician by simplifying complex chemistry concepts and lab essentials including immunoassays, molecular diagnostics, and quality control. A pathophysiologic approach covers diseases that are commonly diagnosed through chemical tests — broken down by body system and category — such as respiratory, gastrointestinal, and cardiovascular conditions. Written by clinical chemistry educator Donna Larson and a team of expert contributors, this full-color book is ideal for readers who may have minimal knowledge of chemistry and are learning laboratory science for the first time. - Full-color illustrations and design simplify complex concepts and make learning easier by highlighting important material. - Case studies help you apply information to real-life scenarios. - Pathophysiology and Analytes section includes information related to diseases or conditions, such as a biochemistry review, disease mechanisms, clinical correlation, and laboratory analytes and assays. - Evolve companion website includes case studies and animations that reinforce what you've learned from the book. - Laboratory Principles section covers safety, quality assurance, and other fundamentals of laboratory techniques. - Review questions at the end of each chapter are tied to the learning objectives, helping you review and retain the material. - Critical thinking questions and discussion questions help you think about and apply key points and concepts. - Other Aspects of Clinical Chemistry section covers therapeutic drug monitoring, toxicology, transplantation, and emergency preparedness. - Learning objectives in each chapter help you to remember key points or to analyze and synthesize concepts in clinical chemistry. - A list of key words Is provided at the beginning of each chapter, and these are also bolded in the text. - Chapter summaries consist of bulleted lists and tables highlighting the most important points of each chapter. - A glossary at the back of the book provides a quick reference to definitions of all clinical chemistry terms.