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Disease Mapping: From Foundations to Multidimensional Modeling guides the reader from the basics of disease mapping to the most advanced topics in this field. A multidimensional framework is offered that makes possible the joint modeling of several risks patterns corresponding to combinations of several factors, including age group, time period, disease, etc. Although theory will be covered, the applied component will be equally as important with lots of practical examples offered. Features: Discusses the very latest developments on multivariate and multidimensional mapping. Gives a single state-of-the-art framework that unifies most of the previously proposed disease mapping approaches. Balances epidemiological and statistical points-of-view. Requires no previous knowledge of disease mapping. Includes practical sessions at the end of each chapter with WinBUGs/INLA and real world datasets. Supplies R code for the examples in the book so that they can be reproduced by the reader. About the Authors: Miguel A. Martinez Beneito has spent his whole career working as a statistician for public health services, first at the epidemiology unit of the Valencia (Spain) regional health administration and later as a researcher at the public health division of FISABIO, a regional bio-sanitary research center. He has been also the Bayesian Hierarchical Models professor for several seasons at the University of Valencia Biostatics Master. Paloma Botella Rocamora has spent most of her professional career in academia although she now works as a statistician for the epidemiology unit of the Valencia regional health administration. Most of her research has been devoted to developing and applying disease mapping models to real data, although her work as a statistician in an epidemiology unit makes her develop and apply statistical methods to health data, in general.
Statistical Methods for Spatio-Temporal Systems presents current statistical research issues on spatio-temporal data modeling and will promote advances in research and a greater understanding between the mechanistic and the statistical modeling communities. Contributed by leading researchers in the field, each self-contained chapter starts w
This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.
Geographic information systems represent an exciting and rapidly expanding technology via which spatial data may be captured, stored, retrieved, displayed, manipulated and analysed. Applications of this technology include detailed inventories of land use parcels. Spatial patterns of disease, geodemographics, environmental management and macroscale inventories of global resources. The impetus for this book is the relative lack of research into the integration of spatial analysis and GIS, and the potential benefits in developing such an integration. From a GIS perspective, there is an increasing demand for systems that do something other than display and organize data. From a spatial analytical perspective, there are advantages to linking statistical methods and mathematical models to the database and display capabilities of a GIS. Although the GIS may not be absolutely necessary for spatial analysis, it can facilitate such an analysis and moreover provide insights that might otherwise have been missed. The contributions to the book tell us where we are and where we ought to be going. It suggests that the integration of spatial analysis and GIS will stimulate interest in quantitative spatial science, particularly exploratory and visual types of analysis and represents a unique statement of the state-of-the-art issues in integration and interface.
Mathematical and Statistical Estimation Approaches in Epidemiology compiles t- oretical and practical contributions of experts in the analysis of infectious disease epidemics in a single volume. Recent collections have focused in the analyses and simulation of deterministic and stochastic models whose aim is to identify and rank epidemiological and social mechanisms responsible for disease transmission. The contributions in this volume focus on the connections between models and disease data with emphasis on the application of mathematical and statistical approaches that quantify model and data uncertainty. The book is aimed at public health experts, applied mathematicians and sci- tists in the life and social sciences, particularly graduate or advanced undergraduate students, who are interested not only in building and connecting models to data but also in applying and developing methods that quantify uncertainty in the context of infectious diseases. Chowell and Brauer open this volume with an overview of the classical disease transmission models of Kermack-McKendrick including extensions that account for increased levels of epidemiological heterogeneity. Their theoretical tour is followed by the introduction of a simple methodology for the estimation of, the basic reproduction number,R . The use of this methodology 0 is illustrated, using regional data for 1918–1919 and 1968 in uenza pandemics.
Progressively more and more attention has been paid to how location affects health outcomes. The area of disease mapping focusses on these problems, and the Bayesian paradigm has a major role to play in the understanding of the complex interplay of context and individual predisposition in such studies of disease. Using R for Bayesian Spatial and Spatio-Temporal Health Modeling provides a major resource for those interested in applying Bayesian methodology in small area health data studies. Features: Review of R graphics relevant to spatial health data Overview of Bayesian methods and Bayesian hierarchical modeling as applied to spatial data Bayesian Computation and goodness-of-fit Review of basic Bayesian disease mapping models Spatio-temporal modeling with MCMC and INLA Special topics include multivariate models, survival analysis, missing data, measurement error, variable selection, individual event modeling, and infectious disease modeling Software for fitting models based on BRugs, Nimble, CARBayes and INLA Provides code relevant to fitting all examples throughout the book at a supplementary website The book fills a void in the literature and available software, providing a crucial link for students and professionals alike to engage in the analysis of spatial and spatio-temporal health data from a Bayesian perspective using R. The book emphasizes the use of MCMC via Nimble, BRugs, and CARBAyes, but also includes INLA for comparative purposes. In addition, a wide range of packages useful in the analysis of geo-referenced spatial data are employed and code is provided. It will likely become a key reference for researchers and students from biostatistics, epidemiology, public health, and environmental science.
"The text is state-of-the-art in its analysis of health disparities from both domestic and international perspectives. Minority Populations and Health: An Introduction to Health Disparities in the United States is a welcome addition to the field because it widens access to the complex issues underlying the health disparities problem. "-- Preventing Chronic Disease/CDC, October 2005 "This is a very comprehensive, evidence-based book dealing with the health disparities that plague the United States. This is a welcome and valuable addition to the field of health care for minority groups in the United States."-- Doody's Publishers Bulletin, August 2005 "Health isn’t color-blind. Racial minorities disproportionately suffer from some diseases, but experts say race alone doesn’t completely account for the disparities. Newsweek's Jennifer Barrett Ozols spoke with Thomas LaVeist, director of the Center for Health Disparities Solutions at Johns Hopkins Bloomberg School of Public Health and author of the upcoming book, "Minority Populations and Health: An Introduction to Health Disparities in the U.S." (Jossey-Bass) about race and medicine. "-- MSNBC/Newsweek interview with author Thomas L. LaVeist, February 2005 "The book is readable and organized to be quickly read with specifics readily retrievable. It is comprehensive and visual."-- Journal of the American Medical Association, September 2005 Minority Populations and Health is a textbook that offers a complete foundation in the core issues and theoretical frameworks for the development of policy and interventions to address race disparities in health-related outcomes. This book covers U.S. health and social policy, the role of race and ethnicity in health research, social factors contributing to mortality, longevity and life expectancy, quantitative and demographic analysis and access, and utilization of health services. Instructors material available at http://www.minorityhealth.com
Simply stated, geography studies the locations of things and the explanations that underlie spatial distributions. Profound forces at work throughout the world have made geographical knowledge increasingly important for understanding numerous human dilemmas and our capacities to address them. With more than 1,200 entries, the Encyclopedia of Geography reflects how the growth of geography has propelled a demand for intermediaries between the abstract language of academia and the ordinary language of everyday life. The six volumes of this encyclopedia encapsulate a diverse array of topics to offer a comprehensive and useful summary of the state of the discipline in the early 21st century. Key Features Gives a concise historical sketch of geography′s long, rich, and fascinating history, including human geography, physical geography, and GIS Provides succinct summaries of trends such as globalization, environmental destruction, new geospatial technologies, and cyberspace Decomposes geography into the six broad subject areas: physical geography; human geography; nature and society; methods, models, and GIS; history of geography; and geographer biographies, geographic organizations, and important social movements Provides hundreds of color illustrations and images that lend depth and realism to the text Includes a special map section Key Themes Physical Geography Human Geography Nature and Society Methods, Models, and GIS People, Organizations, and Movements History of Geography This encyclopedia strategically reflects the enormous diversity of the discipline, the multiple meanings of space itself, and the diverse views of geographers. It brings together the diversity of geographical knowledge, making it an invaluable resource for any academic library.
Handbook of Spatial Epidemiology explains how to model epidemiological problems and improve inference about disease etiology from a geographical perspective. Top epidemiologists, geographers, and statisticians share interdisciplinary viewpoints on analyzing spatial data and space-time variations in disease incidences. These analyses can provide imp
Modeling spatial and spatio-temporal continuous processes is an important and challenging problem in spatial statistics. Advanced Spatial Modeling with Stochastic Partial Differential Equations Using R and INLA describes in detail the stochastic partial differential equations (SPDE) approach for modeling continuous spatial processes with a Matérn covariance, which has been implemented using the integrated nested Laplace approximation (INLA) in the R-INLA package. Key concepts about modeling spatial processes and the SPDE approach are explained with examples using simulated data and real applications. This book has been authored by leading experts in spatial statistics, including the main developers of the INLA and SPDE methodologies and the R-INLA package. It also includes a wide range of applications: * Spatial and spatio-temporal models for continuous outcomes * Analysis of spatial and spatio-temporal point patterns * Coregionalization spatial and spatio-temporal models * Measurement error spatial models * Modeling preferential sampling * Spatial and spatio-temporal models with physical barriers * Survival analysis with spatial effects * Dynamic space-time regression * Spatial and spatio-temporal models for extremes * Hurdle models with spatial effects * Penalized Complexity priors for spatial models All the examples in the book are fully reproducible. Further information about this book, as well as the R code and datasets used, is available from the book website at http://www.r-inla.org/spde-book. The tools described in this book will be useful to researchers in many fields such as biostatistics, spatial statistics, environmental sciences, epidemiology, ecology and others. Graduate and Ph.D. students will also find this book and associated files a valuable resource to learn INLA and the SPDE approach for spatial modeling.