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The idea of one's memory "filling up" is a humorous misconception of how memory in general is thought to work; it actually has no capacity limit. However, the idea of a "full brain" makes more sense with reference to working memory, which is the limited amount of information a person can hold temporarily in an especially accessible form for use in the completion of almost any challenging cognitive task. This groundbreaking book explains the evidence supporting Cowan's theoretical proposal about working memory capacity, and compares it to competing perspectives. Cognitive psychologists profoundly disagree on how working memory is limited: whether by the number of units that can be retained (and, if so, what kind of units and how many), the types of interfering material, the time that has elapsed, some combination of these mechanisms, or none of them. The book assesses these hypotheses and examines explanations of why capacity limits occur, including vivid biological, cognitive, and evolutionary accounts. The book concludes with a discussion of the practical importance of capacity limits in daily life. This 10th anniversary Classic Edition will continue to be accessible to a wide range of readers and serve as an invaluable reference for all memory researchers.
It is only relatively recently that it has been possible to study the neural processes that might underlie working memory, leading to a proliferation of research in this domain. This volume brings together leading researchers from around the world to summarise current knowledge of this field.
The first book to comprehensively explore the cognitive foundations of human spatial navigation Humans possess a range of navigation and orientation abilities, from the ordinary to the extraordinary. All of us must move from one location to the next, following habitual routes and avoiding getting lost. While there is more to learn about how the brain underlies our ability to navigate, neuroscience and psychology have begun to converge on some important answers. In Human Spatial Navigation, four leading experts tackle fundamental and unique issues to produce the first book-length investigation into this subject. Opening with the vivid story of Puluwat sailors who navigate in the open ocean with no mechanical aids, the authors begin by dissecting the behavioral basis of human spatial navigation. They then focus on its neural basis, describing neural recordings, brain imaging experiments, and patient studies. Recent advances give unprecedented insights into what is known about the cognitive map and the neural systems that facilitate navigation. The authors discuss how aging and diseases can impede navigation, and they introduce cutting-edge network models that show how the brain can act as a highly integrated system underlying spatial navigation. Throughout, the authors touch on fascinating examples of able navigators, from the Inuit of northern Canada to London taxi drivers, and they provide a critical lens into previous navigation research, which has primarily focused on other species, such as rodents. An ideal book for students and researchers seeking an accessible introduction to this important topic, Human Spatial Navigation offers a rich look into spatial memory and the neuroscientific foundations for how we make our way in the world.
Dive into the intricate world of Bipolar Affective Disorder with 'Bipolar Affective Disorder Unveiled: Insights, Innovations, and Treatment Perspectives.' This comprehensive treatise illuminates the multifaceted landscape of this condition, offering in-depth insights into its nuances, historical context, and epidemiology. Explore the latest advancements and cutting-edge innovations in neurobiology, genetics, and therapeutic interventions, as this treatise navigates the emerging research terrain. From unraveling genetic predispositions to exploring novel neurostimulation techniques and digital therapeutics, discover a spectrum of innovative approaches reshaping the treatment landscape for Bipolar Affective Disorder. This expertly curated collection delves into the neurological underpinnings, dissecting brain structures, neurotransmitter systems, and molecular pathways implicated in the disorder. Engage with comprehensive chapters on mood episodes, differential diagnoses, and the significance of early recognition in managing this complex condition.
Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
At some point in our lives, most of us have been lost. How does this happen? What are the limits of our ability to find our way? Do we have an innate sense of direction? 'How people get lost' reviews the psychology and neuroscience of navigation. It starts with a history of studies looking at how organisms solve mazes. It then reviews contemporary studies of spatial cognition, and the wayfinding abilities of adults and children. It then considers how specific parts of the brain provide a cognitive map and a neural compass. This book also considers the neurology of spatial disorientation, and the tendency of patients with Alzheimer's disease to lose their way. Within the book, the author considers that, perhaps we get lost simply because our brain's compass becomes misoriented. This book is written for anyone with an interest in navigation and the brain. It assumes no specialised knowledge of neuroscience, but covers recent advances in our understanding of how the brain represents space.
The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. Computational methodologies for implementation on the discovery of biomarkers for neurodegenerative diseases are extensively discussed. This volume focuses on the sessions from the conference regarding computational biology and bioinformatics.
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq