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A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
Botanist Ari lives an isolated life on a space station, tending a lush garden in her quarters. When a woman is given to her as a slave, Ari's ordered life shatters. Her slave is smart, sexy, and seems to know an awful lot about tactics, star charts, and the pirate queen, Mir. A lesbian romance about daring to risk your heart.
Colliding with and confronting The Tempest and postcolonial identity, the poems in Safiya Sinclair's Cannibal explore Jamaican childhood and history, race relations in America, womanhood, otherness, and exile. She evokes a home no longer accessible and a body at times uninhabitable, often mirrored by a hybrid Eve/Caliban figure. Blooming with intense lyricism and fertile imagery, these full-blooded poems are elegant, mythic, and intricately woven. Here the female body is a dark landscape; the female body is cannibal. Sinclair shocks and delights her readers with her willingness to disorient and provoke, creating a multitextured collage of beautiful and explosive poems.
MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
Hidden in the wild forests of the Appalachian Mountains is a school of magic...and mystery. Ezra Bishop's life crumbles apart after a devastating loss, sending her and her twin sister across the country to a prestigious boarding school for bloodline witches. Atwood Preparatory Academy seems like an ideal place for the sisters to attempt to restart their lives, but it isn't long before peace at the school is broken when one of the students goes missing. One of many... When someone close to her is threatened, Ezra is forced to face a mystery that has haunted the school for centuries. Unraveling the truth of the disappearances goes deeper than Ezra is prepared for, until she finds herself digging the grave of a terrorizing secret. Forging a tense alliance with the Headmaster's sons, Ezra may be better off on her own as she discovers the boys are harboring dangerous secrets of their own. But the enemy is already here, and as children continue to go missing, Ezra realizes that she has to lay everything on the line to protect those she cares about...even her life.
Laurie Holcombe is out of a job, out of luck, and out of time. When a prestigious law firm hires her as an assistant to one of its senior partners, it feels like she might finally get back on her feet. All she has to do is put up with the whims of her infuriatingly icy boss, Diana. How hard could that be? Diana Parker is Atlanta's top lawyer and isn't afraid to let everyone know it. She's driven, ruthless, demanding, and stuck in a failing marriage. Too bad she can't run her personal life as well as she runs her ordered office. When a young assistant shows up with bright blue eyes, a cute Southern accent, and a streak of pink hair, Diana's sure she's all wrong for the job. And yet something seems to be pulling her and Laurie Holcombe together, drawing them into a secret, thrilling dance that's far too dangerous for a boss and employee. Can they make rules for this powerful attraction, a way to keep each other at arm's length? But how do you resist the irresistible? A smart, sexy lesbian romance about facing the truth about your desires...and risking everything.
This edition includes: The Jungle 100%: The Story of a Patriot The Moneychangers King Coal: A Novel The Metropolis The Brass Check: A Study of American Journalism The Book of Life (Vol.1&2) The Profits of Religion: An Essay in Economic Interpretation The Fasting Cure Mental Radio (A Book on Parapsychology) A Cadet's Honor; or, Mark Mallory's Heroism On Guard; or, Mark Mallory's Celebration The West Point Rivals; or, Mark Mallory's Stratagem A Prisoner of Morro; or, In the Hands of Enemy They Call Me Carpenter: A Tale of the Second Coming Damaged Goods (The Great Play 'Les Avaries' of Eugene Brieux) Jimmie Higgins A Captain of Industry: Being the Story of a Civilized Man King Midas: A Romance; or, Springtime and Harvest Love's Pilgrimage Samuel the Seeker The Journal of Arthur Stirling; or, The Valley of the Shadow The Overman Sylvia's Marriage The Machine The Naturewoman The Second-Story Man Prince Hagen The Pot Boiler: A Comedy in Four Acts The Menagerie; or, Night in a County Workhouse Letter to John Beardsley The Crimes of the "Times": A Test of Newspaper Decency" Upton Sinclair (1878–1968) was an American author who wrote books in many genres, but in all of them advocating for the moral ethics, better life style for the working people and social justice. Writing during the Progressive Era, Sinclair describes the world of industrialized America from both the working man's point of view and the industrialist. He has also won the Pulitzer Prize for Fiction in 1943.
First published in 1962, on the suggestion of his readers throughout his expansive writing career, this is the self-penned biography of Upton Sinclair, author of hundreds of novels, plays, homilies, diatribes and pamphlets. Written at the age 83, Sinclair at last allows his loyal readership to glean an in-depth look at the man who discovered the Jungle in Armours Meat Industry at 28, founded a Utopian co-operative in 1908, and who muckraked through all of America “to become the finest and most devoted polemicist this country has seen”—from his childhood beginnings in Maryland to his youth in New York through to publication of his first novels and political career and beyond. Of his work, Upton Sinclair says: “The English Queen Mary, who failed to hold the French port of Calais, said that when she died, the word ‘Calais’ would be found written on her heart. I don’t know whether anyone will care to examine my heart, but if they do they will find two words there—’Social Justice.’ For that is what I have believed in and fought for during sixty-three of my eighty-four books. “His is an intellectual’s book dealing with one who made intellectual history, and no self-respecting intellectual tradesman will fail to read it.”—Kirkus Review Illustrated with 17 black-and-white photographs.