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"This important collection provides an epidemiological perspective on the continuing scope of Sickle Cell Disease (SCD) in sub-Saharan Africa, alongside the clinical attempts to provide comprehensive care in a resource-limited setting. The book moves from a clinical profile of SCD to screening for the disease and ongoing patient care. There are chapters on pain management, organ failure, infections and transfusions, as well as nutrition and neurocognitive complications. The book concludes with chapters on anti-sickness medication, cell transplantation and nursing care. The first in a two-volume set offering a multi-disciplinary perspective on SCD, this is a comprehensive resource that applies clinical knowledge to the practical challenges faced in sub-Saharan Africa. It will be important reading for medical students taking courses in haematology as well as those studying Public Health in sub-Saharan Africa. Practitioners in the region will also find it invaluable in developing their understanding of this pervasive disease"--
This fascinating collection examines the socio-economic factors that impact the well-being of patients with sickle cell disease (SCD) in Sub-Saharan Africa and the critical importance of patient advocacy in the region. The book looks at a number of key issues, including the social determinants that influence the spread of the disease, the quality of life of children with SCD, the impact of stigma and the broader psychosocial burden of such a prevalent condition. There are also chapters on policy and Public Health management, including collaborations with non-governmental organisations (NGOs) and global partners. The second in a two-volume set offering a multi-disciplinary perspective on SCD, this insightful collection highlights many of the hidden issues faced across the region. It will be important reading for students of both Public Health and Medicine, as well as practitioners working for governments or NGOs.
"This fascinating collection examines the socio-economic factors that impact the well-being of patients with Sickle-Cell Disease (SCD) in sub-Saharan Africa, and the critical importance of patient advocacy in the region. The book looks at a number of key issues, including the social determinants that influence the spread of the disease, the quality of life of children with SCD, the impact of stigma, and the broader psychosocial burden of such a prevalent condition. There are also chapters on policy and Public Health management, including collaborations with NGOs and global partners. The second in a two-volume set offering a multi-disciplinary perspective on SCD, this insightful collection highlights many of the hidden issues faced across the region. It will be important reading for students of both Public Health and Medicine, as well as practitioners working for governments or NGOs"--
This fascinating collection examines the socio-economic factors that impact the well-being of patients with Sickle-Cell Disease (SCD) in sub-Saharan Africa, and the critical importance of patient advocacy in the region. The book looks at a number of key issues, including the social determinants that influence the spread of the disease, the quality of life of children with SCD, the impact of stigma, and the broader psychosocial burden of such a prevalent condition. There are also chapters on policy and Public Health management, including collaborations with NGOs and global partners. The second in a two-volume set offering a multi-disciplinary perspective on SCD, this insightful collection highlights many of the hidden issues faced across the region. It will be important reading for students of both Public Health and Medicine, as well as practitioners working for governments or NGOs.
This fascinating collection shines a social epidemiological spotlight on the key public health issues affecting sub-Saharan Africa today. Beginning with the legacy of colonial rule, this book outlines the complex interplay between population health and a range of social, economic, and cultural factors. It shows how social epidemiological methods can offer a deeper understanding of population health and features chapters on a range of infectious diseases that continue to have a devastating impact on the region, including Sickle Cell Disease, HIV/AIDS, Leprosy, and Ebola. The final section of this book includes a series of case studies in which social epidemiological methods have been used to explore specific public health issues. Providing a timely overview of the relationship between social systems and human biology in the region, this important book will interest students and researchers across Public Health, Medicine, and African Studies.
This important collection provides an epidemiological perspective on the continuing scope of sickle cell disease (SCD) in sub-Saharan Africa, alongside the clinical attempts to provide comprehensive care in a resource-limited setting. The book moves from a clinical profile of SCD to screening for the disease and ongoing patient care. There are chapters on pain management, organ failure, infections and transfusions, as well as nutrition and neurocognitive complications. The book concludes with chapters on anti-sickness medication, cell transplantation and nursing care. The first in a two-volume set offering a multi-disciplinary perspective on SCD, this is a comprehensive resource that applies clinical knowledge to the practical challenges faced in sub-Saharan Africa. It will be important reading for medical students taking courses in haematology as well as those studying Public Health in sub-Saharan Africa. Practitioners in the region will also find it invaluable in developing their understanding of this pervasive disease.
#1 Best Seller on Sickle Cell Disease (SCD). Sickle cell disease is a group of blood disorders passed down from parents to children. Sickle cell anemia shortens life expectancy by 30 years via bacterial infections, painful swellings, fever, arthritis, leg ulcers, eye, lung & heart damage. Over 100,000 people, mostly African-Americans, in the United States have sickle cell disease. Over 2 million people have sickle cell trait in America. It is estimated that more than 300,000 children are born each year with SCD around the world. This edition of The Management of Sickle Cell Disease (SCD) is organized into four parts: 1. Diagnosis and Counseling 2. Health Maintenance 3. Treatment of Acute and Chronic Complications 4. Special Topics. The original intent was to incorporate evidence-based medicine into each chapter, but there was variation among evidence-level scales, and some authors felt recommendations could be made, based on accepted practice, without formal trials in this rare disorder. The best evidence still is represented by randomized, controlled trials (RCTs), but variations exist in their design, conduct, endpoints, and analyses. It should be emphasized that selected people enter a trial, and results should apply in practice specifically to populations with the same characteristics as those in the trial. Randomization is used to reduce imbalances between groups, but unexpected factors sometimes may confound analysis or interpretation. In addition, a trial may last only a short period of time, but long-term clinical implications may exist. Another issue is treatment variation, for example, a new pneumococcal vaccine developed after the trial, which has not been tested formally in a sickle cell population. Earlier trial results may be accepted, based on the assumption that the change is small. In some cases, RCTs cannot be done satisfactorily (e.g., for ethical reasons, an insufficient number of patients, or a lack of objective measures for sickle cell "crises"). Thus the bulk of clinical experience in SCD still remains in the moderately strong and weaker categories of evidence. Not everyone has an efficacious outcome in a clinical trial, and the frequency of adverse events, such as with long-term transfusion programs or hematopoietic transplants, might not be considered. Thus, an assessment of benefit-to-risk ratio should enter into translation of evidence levels into practice recommendations. A final issue is that there may be two alternative approaches that are competitive (e.g., transfusions and hydroxyurea). In this case the pros and cons of each course of treatment should be discussed with the patient. This book is B&W copy of the government agency publication.
A pioneering work that focuses on the unique diversity of African genetics, offering insights into human biology and genetic approaches.
Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.
The relative lack of information on determinants of disease, disability, and death at major stages of a woman's lifespan and the excess morbidity and premature mortality that this engenders has important adverse social and economic ramifications, not only for Sub-Saharan Africa, but also for other regions of the world as well. Women bear much of the weight of world production in both traditional and modern industries. In Sub-Saharan Africa, for example, women contribute approximately 60 to 80 percent of agricultural labor. Worldwide, it is estimated that women are the sole supporters in 18 to 30 percent of all families, and that their financial contribution in the remainder of families is substantial and often crucial. This book provides a solid documentary base that can be used to develop an agenda to guide research and health policy formulation on female health--both for Sub-Saharan Africa and for other regions of the developing world. This book could also help facilitate ongoing, collaboration between African researchers on women's health and their U.S. colleagues. Chapters cover such topics as demographics, nutritional status, obstetric morbidity and mortality, mental health problems, and sexually transmitted diseases, including HIV.