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"The first nineteen years of Henrietta Brigander's life were distinguished by matchless luxury: summers at Newport and Saratoga, outings on her father's yacht, cotillions on the dance cards of Kennedys and Vanderbilts. Then a schizophrenic break followed by a series of devastating financial setbacks left her destitute on the streets of New York City. Yet Henrietta never looks back, carving out a niche for herself as "Granny Flamingo, aka The Mad Bird Lady of East 14th Street." But when she suspects one of her fellow psychiatric patients has been murdered, Henrietta is forced into yet another role-that of relentless detective"--
"In short, Life Is Simple is enthralling."--Michael Blastland, Prospect A biologist argues that simplicity is the guiding principle of the universe Centuries ago, the principle of Ockham’s razor changed our world by showing simpler answers to be preferable and more often true. In Life Is Simple, scientist Johnjoe McFadden traces centuries of discoveries, taking us from a geocentric cosmos to quantum mechanics and DNA, arguing that simplicity has revealed profound answers to the greatest mysteries. This is no coincidence. From the laws that keep a ball in motion to those that govern evolution, simplicity, he claims, has shaped the universe itself. And in McFadden’s view, life could only have emerged by embracing maximal simplicity, making the fundamental law of the universe a cosmic form of natural selection that favors survival of the simplest. Recasting both the history of science and our universe’s origins, McFadden transforms our understanding of ourselves and our world.
In 2008 Dr. Afrin started coming to understand that a newly recognized type of mast cell disease, now called mast cell activation syndrome (MCAS), was the underlying diagnosis in many patients he was seeing who were each suffering large assortments -- quite different from one patient to the next -- of chronic multisystem inflammatory illnesses of unclear cause. Dr. Afrin soon gained experience that MCAS is far more prevalent than the only mast cell disease previously known to medicine (the rare disease of mastocytosis) and that most MCAS patients, once accurately diagnosed, can eventually find significantly helpful medications targeted at the disease. The frequency and magnitude of the improvements Dr. Afrin has seen -- even the relief that comes from finally having a unifying diagnosis other than "psychosomatism" -- have spurred him to focus in this area, not only tending to the needs of his patients but also pursuing research to advance our understanding of the disease and helping to educate other professionals who in turn can help even more of the many people who have long been suffering not only the symptoms of the disease but also the natural concern of not understanding why one would be so "unlucky" to have acquired so many medical problems. As it turns out, such patients are not so unlucky and truly have just one root issue (and a very common one at that), which has the biological capability to develop, directly or indirectly, into most or all of their previously diagnosed problems. There is a great deal yet to learn about this, but even with just the present very limited understanding, the opportunity to diagnose and help patients with MCAS seems to be enormous and Dr. Afrin felt a description of the disease, written for the general public, might help lead some MCAS patients on a journey to diagnosis and improvement sooner rather than later. Dr. Afrin hopes this book will help people who might have, or do have, MCAS. A portion of the proceeds of purchases of this book will go to support research and education in this area.
Présentation de l'éditeur: "This work offers a new theory of what it means to be a legal person and suggests that it is best understood as a cluster property. The book explores the origins of legal personhood, the issues afflicting a traditional understanding of the concept, and the numerous debates surrounding the topic."
“An original, compelling, and provocative exploration of ethical issues in our society, with thoughtful and balanced commentary. I have not seen anything like it.” —Alan Lightman, author of Einstein’s Dreams Drawing upon the author’s two decades teaching medical ethics, as well as his work as a practicing psychiatrist, this profound and addictive little book offers up challenging ethical dilemmas and asks readers, What would you do? A daughter gets tested to see if she’s a match to donate a kidney to her father. The test reveals that she is not the man’s biological daughter. Should the doctor tell the father? Or the daughter? A deaf couple prefers a deaf baby. Should they be allowed to use medical technology to ensure they have a child who can’t hear? Who should get custody of an embryo created through IVF when a couple divorces? Or, when you or a loved one is on life support, Who says you’re dead? In short, engaging scenarios, Dr. Appel takes on hot-button issues that many of us will confront: genetic screening, sexuality, privacy, doctor-patient confidentiality. He unpacks each hypothetical with a brief reflection drawing from science, philosophy, and history, explaining how others have approached these controversies in real-world cases. Who Says You’re Dead? is designed to defy easy answers and to stimulate thought and even debate among professionals and armchair ethicists alike.
Thirteen Canadian writers from the late nineteenth century to today find intrigue, mystery, and terror in the familiar streets and places of Toronto.
Introduces machine learning and its algorithmic paradigms, explaining the principles behind automated learning approaches and the considerations underlying their usage.
"In an effort to forestall the frailty and isolation of old age, psychiatrist Millard Salter intends to kill himself at the end of the day-but not before he ties up his life's loose ends. These include a with his ne'er-do-well youngest son, Lysander, who at 43 has yet to hold down a paying job; an unscheduled rendezvous with his first wife, Carol, whom he hasn't seen in 27 years; and a brief visit to the grave of his second wife, Isabelle, with whom he fathered an illegitimate child. Yet on what he intends to be the final day of his life, Millard has also assumed a far greater responsibility: to assist a theater director suffering from Lou Gehrig's disease in ending her own life with a helium hood. Complicating this plan is that, during the months since Compassionate Endings has paired Millard with Delilah, the widower has fallen in love with her. As Millard sets about wrapping up his life, he confronts a lifetime of challenges during a single day: a narcissistic colleague intent on having his job, an obsessive administrator browbeating him for a report that will doom his colleagues, and an escaped lynx that is roaming the hospital in search of prey. Meanwhile, as Millard prepares for his impending suicide, his family is planning a surprise for him of its own"--