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Domicile; Intention and Capacity; Pervasive Problems; Substance and Procedure; Jurisdiction to Adjudicate; Due Process Limits on Jurisdiction; Consent; Ownership and Use of Property'; In Rem and Quasi In Rem Jurisdiction Defined; Forum Non Conveniens; Marriage, Divorce and Custody; Torts; Contracts; Property; Construction of the Will; Constitutional Limitations of Choice of Law; Full Faith and Credit Limitations on a State's Choice of Law; Choice of Law in Federal Courts.
Current appellate decisions with supporting pleadings and approved instructions relating to the law of negligence generally, with accompanying editorial comment, cross-references to additional sources, and relevant case annotations.
Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. - Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules - Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents - Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases