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Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science.
This handsomely illustrated survey of contemporary international artists and their approaches to smoke-fired pottery is an inspirational resource for ceramics devotees, from seasoned practitioners to curious collectors.
This volume pays homage to the wonderful teams and players from Azusa, La Verne, Claremont, Pomona, Chino, Cucamonga, Ontario, and Upland. A common thread of all these diverse communities was the establishment of baseball teams and, later, softball teams. Baseball played a critical role in advancing civil and political rights, labor reform, gender equality, educational integration, and cultural legitimacy. These remarkable photographs revive the often-overlooked history of Mexican American baseball in the Greater Pomona Valley.
This updated and expanded new edition resumes the theme of the first edition, and the findings reveal that race, ethnicity, gender, class, and several other variables continue to play a significant and consequential role in the legal decision-making process. The book is structured into three sections, each of which corresponds to a different body of work on Latinos. Section One explores the historical dynamics and influence of ethnicity in law enforcement, and focuses on how ethnicity impacts policing field practices, such as traffic stops, use of force, and the subsequent actions that police departments have employed to alleviate these problems. A detailed examination of critical issues facing Latino defendants seeks to better understand the law enforcement process. The history of immigration laws as it pertains to Mexicans and Latinos explains how Mexicans have been excluded from the United States through anti-immigrant legislation. Latino officers must cope with structural and political issues, the community, and media, as these practices and experiences within the American police system are explored. Section Two focuses on the repressive practices against Mexicans that resulted in executions, vigilantism, and mass expulsions. The topic of Latinos and the Fourth Amendment reveals that the constitutional right of people to be protected against unreasonable searches and seizures has been eviscerated for Latinos, and particularly for Mexicans. Possible remedies to existing shortcomings of the court system when processing indigent defendants are presented. Section Three studies the issue of Hispanics and the penal system. The ethnic realities of life behind bars, probation and parole, the legacy of capital punishment, and life after prison are discussed. Section Four addresses the globalization of Latinos, social control, and the future of Latinos in the U.S. Criminal justice system. Lastly, the race and ethnic experience through the lens of science, law, and the American imagination, are explored, concluding with policy recommendations for social and criminal justice reform, and ultimately humanizing differences. Written for professionals and students of law enforcement, this book will promote the understanding of the historical legacy of brutality, manipulation, oppression, marginalization, prejudice, discrimination, power and control, and white America's continued fear about racial and ethnic minorities.
This book constitutes the refereed proceedings of the 19th Conference of the Spanish Association for Artificial Intelligence, CAEPIA 2020, which was cancelled due to the COVID-19 pandemic, amalgamated with CAEPIA 2021, and held in Malaga, Spain, during September 2021. The 25 full papers presented were carefully selected from 40 submissions. The Conference of the Spanish Association of Artificial Intelligence (CAEPIA) is a biennial forum open to researchers from all over the world to present and discuss their latest scientific and technological advances in Antificial Intelligence (AI). The book is subdivided into the following topical headings: machine learning, optimization and search, and real-world applications. It covers such themes as ambient intelligence and smart environments; computer vision and robotics; constraints, search and planning; creativity and A.I.; education and A.I.; explainable and responsible A.I.; foundation, models and applications of A.I, and others.