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Nanoscience and nanotechnologies are leading to a major point to our understanding of nature. Nanotechnology can be generally defined as creation and use of nano-sized systems, devices, and structures which have special functions or properties because of their small size. This volume on Nanotechnology Applications in Health and Environmental Sciences focuses on biotechnological and environmental applications of nanomaterials. It covers popular and various nanomedical topics such as oncology, genetics, and reconstructive medicine. Additionally, many chapters give leading-edge information on nano-sensor applications and usage in specific disciplines. Also, two chapters on novel subjects have been included on Lantibiotics and microbiota. This book should be useful for nanotechnologists, microbiologists, and researchers interested in nanomedicine and nano-biotechnology, as well as environmental nanotechnology.
This book describes the emerging point-of-care (POC) technologies that are paving the way to the next generation healthcare monitoring and management. It provides the readers with comprehensive, up-to-date information about the emerging technologies, such as smartphone-based mobile healthcare technologies, smart devices, commercial personalized POC technologies, paper-based immunoassays (IAs), lab-on-a-chip (LOC)-based IAs, and multiplex IAs. The book also provides guided insights into the POC diabetes management software and smart applications, and the statistical determination of various bioanalytical parameters. Additionally, the authors discuss the future trends in POC technologies and personalized and integrated healthcare solutions for chronic diseases, such as diabetes, stress, obesity, and cardiovascular disorders. Each POC technology is described comprehensively and analyzed critically with its characteristic features, bioanalytical principles, applications, advantages, limitations, and future trends. This book would be a very useful resource and teaching aid for professionals working in the field of POC technologies, in vitro diagnostics (IVD), mobile healthcare, Big Data, smart technology, software, smart applications, biomedical engineering, biosensors, personalized healthcare, and other disciplines.
The present book is devoted to all aspects of biosensing in a very broad definition, including, but not limited to, biomolecular composition used in biosensors (e.g., biocatalytic enzymes, DNAzymes, abiotic nanospecies with biocatalytic features, bioreceptors, DNA/RNA, aptasensors, etc.), physical signal transduction mechanisms (e.g., electrochemical, optical, magnetic, etc.), engineering of different biosensing platforms, operation of biosensors in vitro and in vivo (implantable or wearable devices), self-powered biosensors, etc. The biosensors can be represented with analogue devices measuring concentrations of analytes and binary devices operating in the YES/NO format, possibly with logical processing of input signals. Furthermore, the book is aimed at attracting young scientists and introducing them to the field, while providing newcomers with an enormous collection of literature references.
This book focusses on recent advances and different research issues in the biosensor technology and also presents theoretical, methodological, well-established and validated empirical work dealing with the technology. The book addresses challenges for the development of a point-of-care test platform. The book also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, multiplex detection of disease biomarkers in real samples. It aims to overcome existing barriers for Lab-on-a-Chip commercialization (lack of cost effective mass manufacturing methods, self-contained, fully autonomous operation and user-friendliness). Different advanced techniques including electrochemical, optical, mass, colorimetric and signal amplification strategies describe early stage disease diagnosis. The book gathers scientific and technological novelties and advancements already developed or under development in the academic and research communities. It covers a vast audience from basic science to engineering and technology experts and learners.
Electrogenerated chemiluminescence (ECL) is a powerful and versatile analytical technique, which is widely applied for biosensing and successfully commercialized in the healthcare diagnostic market. After introducing the fundamental concepts, this book will highlight the recent analytical applications with a special focus on immunoassays, genotoxicity, imaging, DNA and enzymatic assays. The topic is clearly at the frontier between several scientific domains involving analytical chemistry, electrochemistry, photochemistry, materials science, nanoscience and biology. This book is ideal for graduate students, academics and researchers in industry looking for a comprehensive guide to the different aspects of electrogenerated chemiluminescence.
In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. It focuses on analyzing samples in the real world and discusses the biological complexities that make glucose sensing difficult. Covering current implantable devices, next-generation implantable sensing methods, and non-invasive methods for measuring glucose, this book concludes with an overview of possible applications other than diabetes.
Environmental devices help in monitoring the collection of one or more measurements that are used to access the status of an environment. Today, environmental monitoring and analytical methods are among the most rapidly developing branches of analysis. The functionalization of nanomaterials in the field of environmental science has increasing importance with regards to the fabrication of devices. Functionalized nanomaterials reformulate new materials and advanced characteristics for improved application in comparison to old fashion materials and open an opportunity for the development of devices for introducing new technology and techniques for monitoring environmental challenges. The monitoring of these environmental challenges in advances have direct impact on health and sustainability. Functionalized nanomaterials have different mechanical, absorption, optical or electrical properties than original nanomaterials. In fact, major utilization of nanomaterials occurs in their functionalized forms, which are very different from the parent material. This handbook provides an overview of the different state-of-the-art materials, devices and environmental applications of functionalized nanomaterials. In addition, the information offers a platform for ongoing research in the field of environmental science and device fabrication. The main objective of this book is to cover the major areas focusing on the functionalization of nanomaterials, device fabrication along with different techniques and environmental applications of functionalized nanomaterials-based devices. This is an important reference source for materials scientists, engineers and environmental scientsts who are looking to increase their understanding of how functionalized nanomaterial-based devices are being used for environmental monitoring applications. - Helps the reader to understand the basic principles of functionalization of nanomaterials - Highlights fabrication and characterization methods for functionalized nanomaterials-based environmental monitoring devices - Assesses the major challenges of creating devices using functionalized nanomaterials on a mass scale
DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. Electrochemistry of Nucleic Acids and Proteins: Towards Electrochemical Sensors for Genomics and Proteomics is devoted to the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. Volume 1, in the brand new series Perspectives in Bioanalysis, looks at the electroanalytical chemistry of nucleic acids and proteins, development of electrochemical sensors and their application in biomedicine and in the new fields of genomics and proteomics. The authors have expertly formatted the information for a wide variety of readers, including new developments that will inspire students and young scientists to create new tools for science and medicine in the 21st century.* Covers highly sophisticated methods of electrochemical analysis of nucleic acids and proteins* Summarises the present state of electrochemical analysis of nucleic acids and proteins* Includes future trends in the electrochemical analysis in genomics and proteomics
This text details contemporary electroanalytical strategies of biomolecules and electrical phenomena in biological systems. It presents significant developments in sequence-specific DNA detection for more efficient and cost-effective medical diagnosis of genetic and infectious diseases and microbial and viral pathogens. The authors discuss the late
Considers the design, structure and biological activity of ordered films comprised of proteins, polymers, amphiphile molecules and colloidal particles, and assesses the ability of protein/polyion multilayers to mimic living organelles. The book discusses how to reach predetermined locations with proteins and orient molecules while preserving their bioactivity.