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This book provides readers with a clear and reliable account of the extraordinary story of selenium and its role in human health. It is written in a readable and user-friendly manner, and takes into account the considerable amount of fresh information that has been published over the past decade. The book if for the reader who wants to make an informed judgment about the competing claims for and against Selenium’s value as a nutritional supplement.
This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is "too much" of a nutrient.
Selenium plays a fascinating and still poorly understood role in the function of living cells and therefore in human health. Starting with investigations over 60 years ago into its role as a toxic agent in livestock disease, selenium studies have progressed rapidly with the application of tools from immunology and molecular biology. Selenium is now known to be important in human and animal nutrition, has been discovered as a structural component of so-called selenoproteins, and may play a number of physiological roles, ranging from cancer protection to hormone metabolism. Selenium in Biology and Human Health presents research syntheses on a range of topics involving selenium, written by specialists from around the world. It will be of interest to cell biologists and physiologists, nutritional scientists, and animal health researchers.
Selenium is an important micronutrient in humans and animals, despite its toxicity at high concentrations. This first chapter performs a thorough review of selenium bioavailability in food stuffs and human diet. The second chapter reviews the selenium essentiality and toxicity, the aspects related to the selenium dietary supplementation and its daily consumption. The third chapter describes the status of selenium and their metabolites in an antiretroviral therapy context. The next chapter looks at selenium supplementation and autoimmune thyroid diseases. Next, the authors address the association between diabetes type-2 and its levels in serum related to nutritional habits. Then, the preparation of nanosystems based on zero-valent selenium nanoparticles since this essential trace elements carries unique characteristics is explored. Finally, the prospects of using nanoparticles of elementary selenium as a nutrition source are discussed.
This book provides readers with a clear and reliable account of the extraordinary story of selenium and its role in human health. It is written in a readable and user-friendly manner, and takes into account the considerable amount of fresh information that has been published over the past decade. The book if for the reader who wants to make an informed judgment about the competing claims for and against Selenium’s value as a nutritional supplement.
Selenium is arguably the naturally occurring trace element of greatest concern worldwide. In excessive amounts it can lead to toxicosis and teratogenesis in animals, while the impact of selenium deficiency can be even more significant. Contributors from 22 countries explored the connections and inter-relationships between selenium in the environmen
When a city in Connecticut passes a law that requires men to carry women across thresholds at all times, the town's citizens grapple with the practical and theoretical implications of the seemingly pointless ordinance.
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Abstract: A comprehensive, authoritative report of a National Research Council subcommittee reviews current knowledge concerning selenium (Se) in nutrition for nutrition, food, and health professionals. The report focuses on: the chemistry of Se and its analysis; Se distribution in soils, plants, animal feeds, human foods, and water; the Se cycle in nature; biochemical functions of Se (e.g., associations with glutathione peroxidase; nutritional and metabolic inter-associations); Se dietary forms and its absorption, transport, retention, distribution, and metabolism; Se nutritional aspects (dietary requirements and deficiencies in animals, and role in human nutrition); the toxic effects of excess Se; and the effects of high and low Se exposures in human health. A summary of the findings of this report and an extensive list of literature references cited are appended. (wz).
This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.