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Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.
Current state of knowledge and gaps in experimental evidence related to the physiologic role and toxicity of trace elements in human health were presented and discussed at an international joint conference in Hersonissos, Crete-Greece, in October 2007. The conference (ISTERH/NTES/HTES ‘07) constituted the VIIIth Conference of the International Society for Trace Element Research in Humans (ISTERH), the IXth Conference of the Nordic Trace Element Society (NTES), and the VIth Conference of the Hellenic Trace Element Society (HTES). The focus of the conference is put on the topics: Trace minerals as modulators of arterial function Zinc nutriture and the fetal origins of disease Health consequences of trace element deficiencies Copper in neurologic and neurodegenerative diseases Health effects of low dose exposure to toxic metals Environmental stress and mineral homeostasis Molecular mechanisms of metal induced disease Advances in analytical detection of trace elements in biological tissues Mineral elements and molecular signaling as it relates to human disease Is copper involved in carcinogenesis/carcinostatics? Zinc and the common cold The role micronutrients (iodine, iron and zinc) in intellectual development.
The justification for yearbooks is greater than ever as we approach the third millennium, overwhelmed with information. This first edition of the Cytokine Yearbook summarizes the latest advances in the revolutionary field of cytokine research. The work is not a comprehensive reference work, but covers a selection of current themes. The intention is to keep paying attention to current topics in the Yearbooks to come. The editors invited a number of distinguished colleagues, who are international experts in their specific fields, resulting in a high scientific level of the contributions. This Yearbook is required reading for every scientist and physician working in the field of cytokines.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Dr Amrit Rattan K Baidwan- Macfarland presents three essays, the first is on Jurisprudence, entitled; what the law is and what the law ought to be. The complex nature of Jurisprudence based on the original natural justice theory, is examined as well as other theories, which have since been postulated by contemporary jurists. Supreme court decisions are cited to elucidate how natural justice principles engage modern cases today. The second part explores the concepts contained within the original Sanskrit Indian Arthashastra document on diplomacy, used for governance and international affairs, by two of the most famous emperors of India, Chandragupta Maurya, and his successor Ashoka. Finally, the contemporary debate on Israel, Palestine, Syria, Golan Heights, and Jerusalem is presented using key knowledge and contemporary concepts, established by historians and International relations academics. Dr Amrit Rattan K Baidwan-Macfarland – studied public law and governance, international relations, as part of her legal studies. She is a qualified scientist-Jurist- Lawyer, with an interest in public law and foreign affairs and trained in criminal litigation, human rights with her law firms in Scotland, and did a short secondment to India shadowing members of the Attorney General’s department and gaining insights into commonwealth legal systems. She also undertook the study of American legal subjects involving comparative analysis, between two jurisdictions, Scots and American. She gained deep insights in theoretical and pragmatic foreign policy, relations, and affairs, from her academic engagements, with the universities in Scotland, as well as universities in Washington, USA. She enjoyed her research in conflict studies, peace, and security as part of the contemporary living history modules. Through these subjects, the evolving character of global and supra national institutions could be gleaned, as well as the interpretation of civic societies and international diplomacy, exploration of juristic constitutionalism at national and international levels, peace, conflict and the role of religious principles in the Arabian peninsula. AUTHORHOUSE - ACADEMIC PRESS