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Risk assessments are often used by the federal government to estimate the risk the public may face from such things as exposure to a chemical or the potential failure of an engineered structure, and they underlie many regulatory decisions. Last January, the White House Office of Management and Budget (OMB) issued a draft bulletin for all federal agencies, which included a new definition of risk assessment and proposed standards aimed at improving federal risk assessments. This National Research Council report, written at the request of OMB, evaluates the draft bulletin and supports its overall goals of improving the quality of risk assessments. However, the report concludes that the draft bulletin is "fundamentally flawed" from a scientific and technical standpoint and should be withdrawn. Problems include an overly broad definition of risk assessment in conflict with long-established concepts and practices, and an overly narrow definition of adverse health effects-one that considers only clinically apparent effects to be adverse, ignoring other biological changes that could lead to health effects. The report also criticizes the draft bulletin for focusing mainly on human health risk assessments while neglecting assessments of technology and engineered structures.
Risk assessments are often used by the federal government to estimate the risk the public may face from such things as exposure to a chemical or the potential failure of an engineered structure, and they underlie many regulatory decisions. Last January, the White House Office of Management and Budget (OMB) issued a draft bulletin for all federal agencies, which included a new definition of risk assessment and proposed standards aimed at improving federal risk assessments. This National Research Council report, written at the request of OMB, evaluates the draft bulletin and supports its overall goals of improving the quality of risk assessments. However, the report concludes that the draft bulletin is "fundamentally flawed" from a scientific and technical standpoint and should be withdrawn. Problems include an overly broad definition of risk assessment in conflict with long-established concepts and practices, and an overly narrow definition of adverse health effects-one that considers only clinically apparent effects to be adverse, ignoring other biological changes that could lead to health effects. The report also criticizes the draft bulletin for focusing mainly on human health risk assessments while neglecting assessments of technology and engineered structures.
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
The EPA¿s Integrated Risk Info. System (IRIS) contains EPA¿s scientific position on the potential human health effects of exposure to more than 540 chemicals. Toxicity assessments in the IRIS database constitute the first two critical steps of the risk assessment process. Thus, IRIS is a critical component of EPA¿s capacity to support scientifically sound environmental decisions, policies, and regulations. This testimony discusses: (1) highlights of a report, ¿Chemical Assessments: Low Productivity and New Interagency Review Process Limit the Usefulness and Credibility of EPA¿s IRIS:¿; (2) key aspects of EPA¿s revised IRIS assessment process; and (3) progress EPA has made in completing assessments in FY 2008. Charts and tables.
The EPA¿s Integrated Risk Info. System (IRIS) contains EPA¿s position on the potential human health effects of exposure to more than 540 chemicals. Toxicity assessments in the IRIS database constitute the first 2 critical steps of the risk assessment process, which in turn provides the foundation for risk mgmt. decisions. Thus, IRIS is a critical component of EPA¿s capacity to support scientifically sound environmental decisions, policies, and regulations. This testimony discusses: (1) highlights of a 3/08 report, ¿Chemical Assessments: Low Productivity and New Interagency Review Process Limit the Usefulness and Credibility of EPA¿s Integrated Risk Info. System;¿ and (2) key aspects of EPA¿s revised IRIS assessment process, released on 4/10/08.
ENVIRONMENTAL HEALTH The second edition of Environmental Health: From Global to Local, a comprehensive introductory text, offers an overview of the methodology and paradigms of this burgeoning field, ranging from ecology to epidemiology, from toxicology to environmental psychology, and from genetics to ethics. Expert contributors discuss the major issues in contemporary environmental health: air, water, food safety, occupational health, radiation, chemical and physical hazards, vector control, and injuries. Also emphasizing a wide variety of issues of global interest, the thoroughly revised second edition contains updated information on such timely topics as toxicology, exposure assessment, climate change, population pressure, developing nations and urbanization, energy production, building and community design, solid and hazardous waste, and disaster preparedness. In addition, each chapter of Environmental Health includes learning objectives, key points, and discussion questions. Praise for the first edition of Environmental Health "A classic textbook for the dynamic, evolving field of environmental health, thoughtful, well written, well balanced and referenced. An excellent overview of a multifaceted approach to environmental health." AOEC Newsletter (Association of Occupational and Environmental Clinics) "With its many examples, clear explanations, and emphasis on big picture themes and relevance, it is an astonishingly interesting read." Global Public Health "The book's chapters contain highly pertinent insights and information on environmental issues that go beyond the usual boundaries of classic environmental health." Environmental Health Perspectives Winner, AAP Award for Excellence in Professional and Scholarly Publishing
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.