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The EPA¿s ability to effectively implement its mission of protecting public health and the environment relies largely on the integrity and transparency of: (1) its assessments of the potential human health effects of exposure to chemicals; and (2) its fed. advisory committees, which provide independent, expert reviews of EPA¿s scientific work. EPA¿s Integrated Risk Info. System (IRIS) program is critical in developing the agency¿s scientific positions on the potential health effects of exposure to toxic chemicals. EPA¿s Science Advisory Board convenes panels to review EPA¿s scientific assessments. This testimony highlights scientific integrity issues re: (1) the IRIS assessment process; and (2) fed. advisory committee policies and procedures. Illustrations.
Scientific Integrity: EPA's Efforts to Enhance the Credibility and Transparency of Its Scientific Processes
The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.
The EPA Integrated Risk Info. System (IRIS) contains EPA's scientific position on the potential human health effects of exposure to more than 540 chemicals. Toxicity assessments in the IRIS database constitute the first two critical steps of the risk assessment process. Thus, IRIS is a critical component of EPA's capacity to support scientifically sound environmental decisions, policies, and regulations. This testimony discusses: (1) the findings from a March 2008 report ¿Chemical Assessments: Low Productivity and New Interagency Review Process Limit the Usefulness and Credibility of EPA's Integrated Risk Info. System¿ and related testimonies; and (2) a preliminary evaluation of the revised IRIS assessment process EPA issued on May 21, 2009.

EPA's IRIS Program

United States. Congress. House. Committee on Science, Space, and Technology (2011). Subcommittee on Investigations and Oversight

Published: 2011

Total Pages: 328


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This is a print on demand edition of a hard to find publication. The EPA is authorized under the Toxic Substances Control Act (TSCA) to obtain information on the risks of chemicals and to control those that it determines to pose an unreasonable risk. EPA also conducts assessments of chemicals under its Integrated Risk Information System (IRIS) program. Nonetheless, EPA does not have sufficient information to determine whether it should establish controls to limit public exposure to many chemicals that may pose substantial health risks. This testimony addresses EPA's implementation of TSCA and IRIS and options for: (1) obtaining more information on chemical risks; (2) controlling these risks; and (3) sharing more of the information collected under TSCA. Illustrations.