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"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology "Practitioners in epidemiology and oncology will find immense value in this." -JAMA Since its initial publication in 1982, CANCER EPIDEMIOLOGY AND PREVENTION has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans. Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. New and timely chapters on environmental and social-epidemiologic factors include: - The role of social class disparities - The role of obesity and physical inactivity - The potential effects of electromagnetic fields and radiofrequency radiation - The principles of cancer chemoprevention For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authority in the field -- a work of distinction that every lab, library, student, professional, or researcher should have close at hand.
This volume provides the most comprehensive and authoritative account of cancer epidemiology currently available. The long-awaited Second Edition has been greatly expanded and contains much new material on cancer biology, molecular epidemiology, preventive strategies and specific types and sites of cancer. It represents a systematic updating and expansion of its predecessor, while retaining a similar organization. No other source contains so much information on risk factors for cancer. New chapters describe the emerging methodology and applications of molecular genetics such as the stages in neoplastic development and molecular epidemiology in cancer prevention. The epidemiologic reviews of risk factors and causal mechanisms for specific types of cancer include new sections on anus, vagina, and vulva. Among the other new sections is a chapter on the principles and applications of cancer prevention. A critical and authoritative review of the complex issues in preventive oncology, this book will be invaluable in planning strategic preventive interventions at the community level, the workplace, the physicians office, or the clinic.
Drawing widely from international sources, the new edition of this reference book on cancer causes, incidence, mortality and survival patterns, also includes chapters on social class, obesity, physical activity and chemoprevention plus other related topics in the field.
In 28 chapters, Global Epidemiology of Cancer provides a basic overview of the most commonly occurring cancers, their worldwide incidence, and mortality. Designed for the health sciences, particularly those in epidemiology, public health, and medicine, this comprehensive resource is ideal as a primary text for an overview course or seminar on Cancer or Cancer epidemiology. Key Features: • Backed with research and draws upon worldwide information to address the global landscape of cancer. • Offers clear, concise descriptions of each specific type of oncologic disease as well as its epidemiology, etiology, risk factors and preventive factors • Includes a wealth of information on the pathogenesis of the disease as we currently understand it at the molecular level.
"Comprehensive and comprehensible, but also encouraging -- informed by the hope and belief that informed its creation." -Cancer Amid sweeping advances in the science and treatment of cancer, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers students and professionals a definitive, systematic resource for understanding the factors affecting all types of human cancer. This fully updated new edition offers an overview of epidemiology's key concepts and methods as they relate to cancer (including the emerging potential of biomarkers) as well as site-specific chapters on individual cancers' natural history, pathology, descriptive epidemiology, and etiology. Taken together, these chapters forge connections between established science and the ongoing evolution of this dynamic field. Crisply and concisely written by an assembly of internationally recognized researchers, the TEXTBOOK OF CANCER EPIDEMIOLOGY offers a superlative introduction to the subject's consensuses and controversies for those embarking on their careers and a ready reference for seasoned professionals.
A Quick Guide to Cancer Epidemiology is an ideal addition to Springer Briefs in Cancer Research. The Brief provides core concepts in cancer epidemiology and also gives a snapshot of the epidemiology of seventeen human cancers. The Brief aims to provide-with quantitative focus-estimates of the global burden of neoplasms, of recent and likely future trends, distribution, causes and strategies for prevention for major groups of cancers. Finally, the Brief will give an overview of severals factors that cause cancer including dietary factors, tobacco smoking, obesity and alcohol consumption.
Epidemiologic Studies in Cancer Prevention and Screening is the first comprehensive overview of the evidence base for both cancer prevention and screening. This book is directed to the many professionals in government, academia, public health and health care who need up to date information on the potential for reducing the impact of cancer, including physicians, nurses, epidemiologists, and research scientists. The main aim of the book is to provide a realistic appraisal of the evidence for both cancer prevention and cancer screening. In addition, the book provides an accounting of the extent programs based on available knowledge have impacted populations. It does this through: 1. Presentation of a rigorous and realistic evaluation of the evidence for population-based interventions in prevention of and screening for cancer, with particular relevance to those believed to be applicable now, or on the cusp of application 2. Evaluation of the relative contributions of prevention and screening 3. Discussion of how, within the health systems with which the authors are familiar, prevention and screening for cancer can be enhanced. Overview of the evidence base for cancer prevention and screening, as demonstrated in Epidemiologic Studies in Cancer Prevention and Screening, is critically important given current debates within the scientific community. Of the five components of cancer control, prevention, early detection (including screening) treatment, rehabilitation and palliative care, prevention is regarded as the most important. Yet the knowledge available to prevent many cancers is incomplete, and even if we know the main causal factors for a cancer, we often lack the understanding to put this knowledge into effect. Further, with the long natural history of most cancers, it could take many years to make an appreciable impact upon the incidence of the cancer. Because of these facts, many have come to believe that screening has the most potential for reduction of the burden of cancer. Yet, through trying to apply the knowledge gained on screening for cancer, the scientific community has recognized that screening can have major disadvantages and achieve little at substantial cost. This reduces the resources that are potentially available both for prevention and for treatment.
This Cancer Prevention book series aims to complement the research reported in the journal Cancer Causes and Control. Volumes in this series will summarize the state of the science from causes to prevention of cancer. The scope will be international. The past 20 years has seen an explosion of epidemiologic material on the causes of cancer. Examples include the growing number of studies of physical activity and colon cancer which have emerged and the numerous studies of components of diet such as alcohol and the risk of specific cancers. Major shifts in resource allocation now focus on translation of this new knowledge to actual cancer prevention programs. Researchers, practicing clinicians, and those who write and implement public health policy need this information summarized in an easily accessible format. The abundance of knowledge, increasing understanding of how to communicate risk of cancer to the public, and greater public awareness of cancer, make the coming years ones in which we will see many new attempts at widespread cancer prevention programs. For example, the U.S. Centers for Disease Control and Prevention launched a national colon cancer awareness campaign in early 1999.
Epidemiological studies show that cancer incidence is far more dependent on the conditions of life than previously supposed. Classically, cancers occurred with heavy exposure to a specific occupational hazard, or were associated with habits. In some instances, research shows, the incidence of cancer falls when the method of work or the associated habit is changed. In short, variation in incidence is now known to be the rule rather than the exception in cancer. No cancer that occurs with even moderate frequency, occurs everywhere and always to the same extent. Sometimes it is even epidemic, similar in scale to an epidemic of infectious disease, but modified by the fact that the induction period may be as much as thirty years.Prevention of cancer is now coming to be regarded as a practicable alternative to its cure. We remain almost totally ignorant of how cancer is produced at the cellular level and, until we know this, our methods of prevention are liable to be cumbersome and inefficient. Ethical considerations and the time scale of the disease make it impossible to obtain experimental evidence in man and what action to take has been determined from observing nature's experiments and by analogy from experiments in animals.The evidence from epidemiological studies is of particular interest. Such studies suggest relationships that would never be thought of in the ordinary course of laboratory work and results that are directly relevant to the problems of human disease. The large numbers at risk and the intensity of the medical care to which people with cancer are subjected, make it possible to recognize relatively small improvements. Such practical decisions, based on information thus obtained, have largely eliminated the risk of cancer due to occupational hazards in several industries.
According to the World Health Organization's 2008 GLOBOCAN report, 64% of global cancer deaths — and 56% of cancer cases — were registered in countries in Africa, Asia, or Latin America. So while cancer is unquestionably a global burden, its reach in the developing world points to the need for specialized study on cancer in these countries. Cancer Epidemiology: Low- and Middle-Income Countries and Special Populations reviews the current status of cancer epidemiologic research and training — rationale, requisite infrastructure, methodologic principles, and illustrative examples in low- and middle-income countries — in order to facilitate future advances by trained health professionals. The result is a valuable resource for both program leaders and graduate and post-graduate students pursuing careers in international cancer epidemiologic research.