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In bacteriology's Golden Age (roughly 1870-1890) European physicians focused on bacteria as causal agents of disease. Advances in microscopy and laboratory methodology--including the ability to isolate and identify micro-organisms--played critical roles. Robert Koch, the most well known of the European researchers for his identification of the etiological agents of anthrax, tuberculosis and cholera, established in Germany the first teaching laboratory for training physicians in the new methods. Bacteriology was largely absent in early U.S. medical schools. Dozens of American physicians-in-training enrolled in Koch's course in Germany, and many established bacteriology courses upon their return. This book highlights those who became acknowledged leaders in the field and whose work remains influential.
Chronicles the life of Robert Koch, focusing on his contributions to the fields of medicine and bacteriology, discussing his research trips to India, findings on the causes of tuberculosis, cholera, and anthrax, postulates, Nobel Prize, and other related topics.
In the nineteenth century, the new field of medical bacteriology identified microorganisms and explained how they spread disease. This book interweaves the history of this discipline and the biography of one of its founders, Nobel Prize–winning German physician Robert Koch (1843–1910). Koch contributed to modern medicine by inventing or improving fundamental techniques such as bacterial staining, solid culture media, mass pure cultures, and the use of animal models. His discoveries, which dominated medical science at the turn of the last century, are epitomized in a set of rules named after him. "Koch's Postulates" are still invoked today in attempts to prove the causal involvement of pathogens in infectious diseases. In a double history, Christoph Gradmann narrates the development of a discipline and the biography of a scientist. Drawing on Koch's extensive laboratory notes, Gradmann details how Koch developed his scientific method and discovered the bacterial causes of anthrax, tuberculosis, and cholera. Koch tried to bring this knowledge to clinical medicine by developing medicines that would specifically target the bacterial pathogens he identified. And Koch’s passion for personal travel developed into a career signature, as he became a pioneer in the study of tropical diseases. A fascinating look into Koch's personality and his experimental work in medical bacteriology, Laboratory Disease reveals both the biographical and the historical roots of our modern understanding of infectious diseases.
The riveting history of tuberculosis, the world’s most lethal disease, the two men whose lives it tragically intertwined, and the birth of medical science. In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing. When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s “remedy” was either sloppy science or outright fraud. But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes. Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.
Shows how the scientific knowledge about the role of microorganisms in disease made its way into American popular culture.
This book presents a collection of short biographies and works of the pioneers in pathology. The alphabetically arranged entries allow readers to quickly and easily find the information they need.
Science, Medicine, and Animals explains the role that animals play in biomedical research and the ways in which scientists, governments, and citizens have tried to balance the experimental use of animals with a concern for all living creatures. An accompanying Teacher's Guide is available to help teachers of middle and high school students use Science, Medicine, and Animals in the classroom. As students examine the issues in Science, Medicine, and Animals, they will gain a greater understanding of the goals of biomedical research and the real-world practice of the scientific method in general. Science, Medicine, and Animals and the Teacher's Guide were written by the Institute for Laboratory Animal Research and published by the National Research Council of the National Academies. The report was reviewed by a committee made up of experts and scholars with diverse perspectives, including members of the U.S. Department of Agriculture, National Institutes of Health, the Humane Society of the United States, and the American Society for the Prevention of Cruelty to Animals. The Teacher's Guide was reviewed by members of the National Academies' Teacher Associates Network. Science, Medicine, and Animals is recommended by the National Science Teacher's Association NSTA Recommends.
"The practice of inoculation for the prevention of disease is one of considerable antiquity. The period of its discovery can only be conjectured, but there is little doubt that even in remote times it mush have been recognised by man, that certain diseases occur once only durng the life of an individual, or that after recovery he is generally immune against further attacks of the same disease." -- Chapter 1, Page 10.
Pasteurization, penicillin, Koch's postulates, and gene coding. These discoveries and inventions are vital yet commonplace in modern life, but were radical when first introduced to the public and academia. In this book, the life and times of leading pioneers in microbiology are discussed in vivid detail, focusing on the background of each discovery and the process in which they were developed — sometimes by accident or sheer providence.