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The difficulties associated with making risk assessments on the basis of experimental results are familiar to practitioners in many fields engineering, epidemiology, chemistry, etc. These difficulties are particularly common in problems that have dynamic and stochastic characteristics driven by multiple purposes and goals, with complex interconnections and inter dependencies. Acquiring an appropriate data base, processing and analyzing model results, and transmitting these results at an appropriate technical, social, political, and institutional level are additional difficulties that must be addressed. This book is grounded on the premise that risks are best assessed on the basis of experimental results and sound mathematical analyses, coupled with the knowledge of experts. The carcinogenicity prediction and battery selection (ePBS) approach described herein provides a systematic mechan ism-a synthesis of systems and statistical and decision analyses-to aid researchers and decision makers in the critical field of carcinogenicity prediction in selecting an appropriate battery of tests to use and in translating experimental results into information that can be used as an aid to decision making.
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
The authoritative guide to the application of EMDR to war and terrorism trauma, Light in the Heart of Darkness provides an invaluable tool for all therapists looking to integrate these innovative approaches into their practices. Offering one of the most thorough overviews of EMDR treatment, this book can also be used as a general reference for all practitioners looking to broaden their understanding and care of trauma patients.
Originally published in 1998, Psycho-Oncology was the first comprehensive text in the field and remains the gold standard today. Previously led by Dr. Jimmie C. Holland, the founder of the field, this new edition is edited by a team of internationally renowned experts in psycho-oncology. The text reflects the interdisciplinary nature and global reach of this growing field. It covers evidence-based clinical practice guidelines from around the world, survivorship issues, psychotherapeutic interventions, and psychopharmacologic interventions. Thoroughly updated and developed in collaboration with the American Psychosocial Oncology Society and the International Psycho-Oncology Society, the fourth edition is a current, comprehensive reference for psychiatrists, psychologists, oncologists, hospice workers, and social workers seeking to understand and manage the psychological issues involved in the care of persons with cancer and the psychological, social, and behavioral factors that contribute to cancer risk and survival.
Highly Commended in the Obstetrics and Gynaecology category of the 2010 BMA Medical Book Competition Brand new edition of the world's leading text on prenatal diagnosis This 6th Edition of Genetic Disorders and the Fetus maintains it's pre-eminence as the major repository of facts about prenatal diagnosis. It provides a critical analysis and synthesis of established and new knowledge based on the long experience of authorities in their respective fields. A broad international perspective is presented through authoritative contributions from authors in 11 countries. All chapters and guidelines have been updated to reflect contemporary practice. New chapters have been introduced on: The use of chromosomal microarrays in prenatal diagnosis The social, legal and public policy issues with special reference to international approaches The important peroxisomal and related fatty acid oxidation disorders Extensive tables and clear illustrations assist in differential diagnosis, gene identification and diagnostic modes. The recognition of many new and unresolved challenges should provide inspiration for novel research initiatives. The guidance provided and the insights and perspectives of these authors make this volume a valuable and indispensable resource for all whose focus is securing fetal health through prenatal diagnosis. Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment is an essential resource for all engaged in prenatal genetic diagnosis, especially obstetricians, maternal-fetal medicine specialists, medical geneticists, genetic counsellors, and pediatricians, but also many other specialties.