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cryoEM, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods and new developments in recording images, the creation, evaluation and validation of 3D maps from the images, model building into maps and refinement of the resulting atomic structures, and applications of essentially single particle methods to helical structures and to sub-tomogram averaging. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods that determine the structures of biological molecules, a vital step for understanding their function - Contains the technical developments underpinning the advances of cryoEM and captures the exciting insights that have resulted
Reclaiming the American Revolution examines the struggles for political ascendancy between Federalists and the Republicans in the early days of the American Republic. Watkins views the struggle through the lens of the Kentucky and Virginia Resolutions, charters written by Thomas Jefferson and James Madison respectively, that were responses to the Alien and Sedition Acts passed by Federalists that, among other things, made criticism of the federal government a crime. Viewing those acts as a threat to states' rights, as well as indicative of a national government that sought supreme power, the Resolutions restated the principles of the American Revolution and sought to return the nation to the tenets of the Constitution, in which rights for all were protected by checking the power of the national government.
"In the 20th and 21st century revolutions have become more urban, often less violent, but also more frequent and more transformative of the international order. Whether it is the revolutions against Communism in Eastern Europe and the USSR; the "color revolutions" across Asia, Europe and North Africa; or the religious revolutions in Iran, Afghanistan, and Syria; today's revolutions are quite different from those of the past. Modern theories of revolution have therefore replaced the older class-based theories with more varied, dynamic, and contingent models of social and political change. This new edition updates the history of revolutions, from Classical Greece and Rome to the Revolution of Dignity in the Ukraine, with attention to the changing types and outcomes of revolutionary struggles. It also presents the latest advances in the theory of revolutions, including the issues of revolutionary waves, revolutionary leadership, international influences, and the likelihood of revolutions to come. This volume provides a brief but comprehensive introduction to the nature of revolutions and their role in global history"--
Overcome your struggles. Fulfill your deepest longings. Your whole life awaits you. Many people today are struggling with unprecedented levels of anxiety, hurt, doubt, guilt, and shame. Medical and mental health professionals confirm that much of the dysfunction and disconnectedness we experience in life stems from unresolved relational and emotional hurts. These hurts leave us with unfulfilled God-given longings that we seek to fulfill through unhealthy behaviors and relationships. Yet, our struggles aren't random; they're signals that when answered, can pave our way towards a thriving life. In Free to Thrive, Josh McDowell and Ben Bennett invite you on a journey of healing and will teach you how to overcome unwanted behaviors by engaging your unmet longings. With a blend of hard-won wisdom and youthful energy, they present: Biblical teaching Recent neuroscientific research Time-tested principles Personal stories of deliverance Practical tools Opportunities for reflection No matter what you are struggling with, it is possible to experience the spiritual, emotional, and relational wholeness that God wants you to have--and live the thriving life you were made for.
Many people today are looking for opportunities to bring the spiritual into their everyday lives in non-traditional ways. Their days are so busy they can't imagine how they can fit in time to kneel or sit in prayer on a regular basis. As a result, they fly from one activity to the next at breakneck speed, always looking forward to some nonexistent time in the future when things will slow down long enough to allow them to breathe, center themselves, and pray. Everyday Divine: A Catholic Guide to Active Spirituality helps busy readers explore different ways to achieve a place of stillness and peace while remaining very much in the world. In fact, the day-to-day activities of life become the pathway to prayer-even the prayer itself. Drawing on Catholic tradition, from the Desert Fathers and Mothers to ancient monastics to modern-day saints and sages, Everyday Divine looks at how we can adapt these ancient practices for modern times, quoting holy men and women on various methods and offering practical instructions and suggestions to help people put them into practice. Readers learn how to find spiritual peace while immersed in everyday activities, such as: - Housework and chores - Workouts and exercise - Cooking, eating, and fasting - Listening to music - Traveling and making pilgrimages - Living among the noise of daily life The book also includes personal stories from the author and others, and will weave in practices from specific spiritualities-such as Franciscan, Benedictine, and Trappist-to show how these practices fit into the bigger Catholic picture.
Explains how bold efforts at profound progressive change provoked a powerful reactionary backlash that led to the imposition of brutal, regressive dictatorships.