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Traditionally, industrial hygienists have sought to prevent excessive exposure to chemicals in industry by setting standards for concentrations of chemicals in ambient air. Standards for chemicals in air applied by the American Conference of Governmental Industrial Hygienists include: the maximum allowable concentration (MAC), the threshold limit value (TLV), and the emergency exposure limit (EEL) However, the monitoring of air concentrations only considers exposure by inhalation and is not indicative of the actual uptake or total body burden of chemicals by exposed workers. During the past 20 years numerous procedures have been developed for the analysis of industrial chemicals in biological specimens collected from workers. Such biological monitoring takes into consideration absorption of chemicals by all routes of absorption and differences in individual exposures. The goal of biological monitoring is to detect excessive exposure in workers before the occurrence of detectable adverse health effects.
The bestselling resource on industrial chemical assessment just got better. A practical guide to biological monitoring for industrial chemical exposure assessment, the THIRD EDITION of INDUSTRIAL CHEMICAL EXPOSURE: GUIDELINES FOR BIOLOGICAL MONITORING has been completely revised to include the latest developments in the field. In addition to an update of each chapter, major revisions have been made to take into consideration new information available since the publication of the second edition. SEE WHAT'S NEW IN THE THIRD EDITION: Major changes to the sections on lead, benzene, trichloroethylene, and dimethylformamide Fourteen completely new topics: bromine, molybdenum, perchlorate, platinum, n-heptane, ethene, 1,3-butadiene trimethylbenzene, naphthalene, terpenes, acrylamide, pesticides, tetrahydrofuran, methyl tertiarybutyl ether, n-nitrosodiethylamine Discussion of the metabolic fate of chemicals Increased information on the threshold of adverse effects levels Development of biological monitoring methods for assessing the internal dose of additional chemicals This authoritative book summarizes what is known about biological monitoring for inorganic, organic and organometallic substances. It provides a summary table with practical recommendations, giving you quick and easy access to the data. With INDUSTRIAL CHEMICAL EXPOSURE: GUIDELINES FOR BIOLOGICAL MONITORING you will understand the objectives of biological monitoring, the types of biological monitoring methods, their advantages and limitations, as well as practical aspects that must be considered before initiating a biological monitoring program.
An authoritative and practical guide to identifying major health issues in the workplace with an overview of common control approaches. Contains detailed surveys of work tasks in a wide range of industries, enabling readers to recognize health problems in facility design and operation and to relate medical symptoms to job exposure. New to this edition: discussion of microelectronics, chemical processing and plastics fabrication; increased coverage of published exposure information; epidemiologic and other health status studies.
Chemical Exposures: Low Levels and High Stakes explains how day-to-day variations in chemical exposure may cause unusual and seemingly unpredictable symptoms, including many that have been termed psychosomatic in the past. It describes how everyday, low-level chemical exposures may cause fatigue, memory impairment, headaches, mood changes, breathing difficulties, digestive problems, and a host of chronic unexplained illnesses including chronic fatigue syndrome, Gulf War syndrome, and sick building syndrome. The authors are the first writers to clearly describe and document the process of adaptation, a concept that provides a rational and scientific basis for understanding these symptoms. In the Second Edition of this professionally acclaimed work, the authors offer evidence for an emerging new theory of disease-toxicant-induced loss of tolerance-which may have far-reaching implications for medicine, public health, and environmental policy. Based on a report commissioned by the New Jersey Department of Health that won the World Health Organization's Macedo Award, Chemical Exposures is the most comprehensive book ever written on sensitivity to low level chemical exposure and the many health effects associated with it. This work clarifies the nature of chemical sensitivity, shows how it differs from traditional allergies and toxicity, and suggests how federal and state governments can help those who are affected. The book identifies four major groups of people with hypersensitivity to low levels of chemicals: occupants of tight buildings, industrial workers who handle chemicals, residents of communities exposed to toxic chemicals, and individuals with random and unique exposures to various chemicals. The fact that similar symptoms are being reported by members of these demographically diverse groups not only points to a serious problem, it may also contribute to a better understanding of chemical sensitivity. Included are a number of features that will be invaluable to health professionals: * Clear, concise explanations of technical material * The most extensive bibliography to date on the subject * Tables contrasting different medical approaches * Descriptions of recent research and proposed mechanisms * An annotated bibliographical appendix highlighting illnesses that have been linked to environmental exposures * Policy recommendations for federal and state governments "Clinicians and policymakers would do well to read and heed the advice of this book."-Journal of the American Medical Association "Clinicians, researchers, and policymakers in this field would be well advised to read this landmark book."-American Public Health Association Newsletter "A milestone in the evolution of multiple chemical sensitivity."-Chemical and Engineering News ".groundbreaking and accessible.balanced and scholarly.essential reading for risk assessors, physicians, psychologists, attorneys concerned with toxic torts, public health officials, regulators, government decisionmakers, medical and environmental researchers, as well as laypersons."-Journal of Risk Analysis
The NIOSH Pocket Guide to Chemical Hazards presents information taken from the NIOSH/OSHA Occupational Health Guidelines for Chemical Hazards, from National Institute for Occupational Safety and Health (NIOSH) criteria documents and Current Intelligence Bulletins, and from recognized references in the fields of industrial hygiene, occupational medicine, toxicology, and analytical chemistry. The information is presented in tabular form to provide a quick, convenient source of information on general industrial hygiene practices. The information in the Pocket Guide includes chemical structures or formulas, identification codes, synonyms, exposure limits, chemical and physical properties, incompatibilities and reactivities, measurement methods, respirator selections, signs and symptoms of exposure, and procedures for emergency treatment.
A practical guide to biological monitoring for industrial chemical exposure assessment, this authoritative book summarizes what is known about biological monitoring for inorganic, organic, and organometallic substances. The authors explore the objectives of biological monitoring, the types of biological monitoring methods, their advantages and limitations, as well as practical aspects that must be considered before initiating a biological monitoring program. They identify the potential biological markers for assessing exposure or body burden and include summary tables with practical recommendations that give readers quick and easy access to the data.
The National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.
Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Since Operation Desert Shield/Desert Storm, Gulf War veterans have expressed concerns about health effects that could be associated with their deployment and service during the war. Although similar concerns were raised after other military operations, the Gulf War deployment focused national attention on the potential, but uncertain, relationship between the presence of chemical and biological (CB) agents and other harmful agents in theater and health symptoms reported by military personnel. Strategies to Protect the Health of Deployed U.S. Forces which is one of the four two-year studies, examines the detection and tracking of exposures of deployed personnel to multiple harmful agents.
Provides information on proper chemcial equipment handling including, purchasing, storage, use, and disposal.