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This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
The study of human laterality or cerebral asymmetry has attracted particular attention in research involving such areas as pattern recognition and language and motor skills. Brings readers up to date on the rapid progress in this area of neuropsychology. It describes the latest research on laterality in nonhuman species, going on to examine clinical, commissurotomy and normative studies of human cerebral asymmetry. Explores theoretical models of hemispheric specialization and interaction, language in the °minor° (right) hemisphere and language, tool use, dextrality and bipedalism in human evolution. Succeeding chapters discuss handedness, sex and developmental aspects, particularly individual and developmental differences in cognitive abilities. Recent popular generalizations concerning °hemisphericity° are also described.
Is "right-brain" thought essentially creative, and "left-brain" strictly logical? Joseph B. Hellige argues that this view is far too simplistic. Surveying extensive data in the field of cognitive science, he disentangles scientific facts from popular assumptions about the brain's two hemispheres. In Hemispheric Asymmetry, Hellige explains that the "right brain" and "left brain" are actually components of a much larger cognitive system encompassing cortical and subcortical structures, all of which interact to produce unity of thought and action. He further explores questions of whether hemispheric asymmetry is unique to humans, and how it might have evolved. This book is a valuable overview of hemispheric asymmetry and its evolutionary precedents.