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Investigation of the influence of creep-exposure on the mechanical properties of Rene' 41 at room temperature was continued. The results showed that thermally-induced structural changes reduced the strength and ductility for exposures at temperatures from 1400 to 1800 F. Reduced yield strength was due mainly to a decrease in the measured volume fraction of gamma prime precipitate and secondarily to an increase in the gamma prime particle size. For the conditions studied, gamma prime was sufficiently stable up to 1400 F so that yield strength was not affected. Ductility was reduced by thermally-induced carbide precipitation in the grain boundaries in the temperature range from 1400 to 1800 F. Ductility reached a minimum after about 100 hr at 1700 to 1800 F and was not further decreased by creep. Creep had little effect on the gamma prime reactions.