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Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Probabilistic Safety Assessment (PSA) is a structured, comprehensive, and logical analysis method aimed at identifying and assessing risks in complex technological systems, such as the nuclear power plants. It is also known as probabilistic risk assessment – PRA. This book presents the theoretical basis to understand the numerous and complex aspects that are covered by PSA and it will help the reader to better understand and to effectively manage risks. The book provides PSA methods and techniques and it includes recommended procedures that are based on the experience of the authors and applicable to different levels and types of PSA that are used for nuclear power plants applications. It can be used as extra reading for PSA courses for practitioners and it provides quantitative risk methodology documentation for PSA.
Reliability and Probabilistic Safety Assessment in Multi-Unit Nuclear Power Plants presents the risk contributions from single and multi-unit Nuclear Power Plants to help aggregate the risks that may arise due to applicable hazards and operating states. The book combines the key features of multi-unit risk assessment in one resource, reviewing the practices adopted in various countries around the globe to exemplify the dependencies between units on a site. These dependencies include multi-unit interactions, environmental stresses, the sharing of systems, and the sharing of human resource in a control room, factors which can all introduce an increase potential for heightened accident conditions. This book helps readers systematically identify events and evaluate techniques of possible accident outcomes within multi-units. It serves as a ready reference for PSA analysts in identifying a suitable site and the sharing of resources, while carrying out multi-unit risk assessments to ensure the safety of the public and the environment. It will also be valuable for nuclear researchers, designers and regulators of nuclear power plants, nuclear regulatory agencies, PSA engineers and practicing safety professionals. - Provides a framework for nuclear and PSA researchers and professionals on the design and operation of multi-unit risk assessments - Reviews practices adopted in various regions around the globe to analyze dependencies between units - Includes modeling techniques of inter-connections and shared resources, as well as risk aggregation
Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.
This ground-breaking book addresses the challenge of regulatory delivery, defined as the way that regulatory agencies operate in practice to achieve the intended outcomes of regulation. Regulatory reform is moving beyond the design of regulation to address what good regulatory delivery looks like. The challenge in practice is to operate a regulatory regime that is both appropriate and effective. Questions of how regulations are received and applied by those whose behaviour they seek to control, and the way they are enforced, are vital in securing desired regulatory outcomes. This book, written by and for practitioners of regulatory delivery, explains the Regulatory Delivery Model, developed by Graham Russell and his team at the UK Department for Business, Energy and Industrial Strategy. The model sets out a framework to steer improvements to regulatory delivery, comprising three prerequisites for regulatory agencies to be able to operate effectively (Governance Frameworks, Accountability and Culture) and three practices for regulatory agencies to be able to deliver societal outcomes (Outcome Measurement, Risk-based Prioritisation and Intervention Choices). These elements are explored by an international group of experts in regulatory delivery reform, with case studies from around the world. Regulatory Delivery is the first product of members of the International Network for Delivery of Regulation.