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This book presents recent progress in cystic fibrosis research. Living a healthy life is one's ultimate goal, but the genetics behind the creation of each human is not same. As a curse of human suffering, certain people are born with congenital defects in their menu of the genome. The complexity of cystic fibrosis condition has impacts on several organ systems of the human body perplexing further with secondary infections. It is a complicated disease and scientists across the globe are still trying to comprehend it and formulate a cure because though they narrowed it down to a single target gene, the effects of this disease reach several unfamiliar corners of the human body. Decades of scientific research in the field of chronic diseases has certainly escalated the level of life expectancy. Scientists and researchers from across the globe have contributed significant information in this all-inclusive book which covers two broad sections: therapeutic options and disease management.
Cystic fibrosis (CF), also known as munoviscidosis, is a chronic genetic disease involving the dysfunction of the exocrine glands. This dysfunction is manifested as a deficiency in pancreatic enzymes, accumulation of mucous in airways, and excess salt in sweat. Cystic fibrosis was previously restricted to infancy and childhood but developments in medical treatment and therapy have extended survival considerably. This book includes within its scope research aimed at understanding the genetic linkage in cystic fibrosis, as well as improving the diagnosis and treatment of this disease in both children and adults. Leading-edge scientific research from throughout the world is presented.
Cystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical case, presenting in middle age, with the potential for complications in virtually every system of the body. In the past few years there has been an explosion of knowledge of the basic science of the defect. The editors have therefore invited the leading scientists and clinicians in the field of cystic fibrosis to describe the recent advances in this disease. Although there are many 'Recent Advances' texts, previous books have been selective in their choice of topics. This book is the first to cover the entire field of this complex disease, and encompasses the rapidly moving topics of the basic molecular and cellular biology as well as the recent multi-system, multi-disciplinary advances in the clinical care of patients. The authors have been charged with writing only about new developments and not to rehash old literature. The bulk of the references is therefore less than five years old. This book addresses all professionals who treat cystic fibrosis and want to have an up-date of new findings in the field, particularly of those outside their immediate specialisation. It will also be useful for basic researchers interested in related scientific areas and the clinical context of their work.
Proceedings of an international workshop held in Sestri Levante (Genoa), Italy, April 9--11, 1990
Cystic fibrosis, a genetic disorder in children and young adults, is a multisystemic disease that mainly affects the lungs. Advances and improvements in the diagnosis and management of this condition have led to increased overall and symptom-free survival in cystic fibrosis patients. This book examines recent advances in the field and presents an evidence-based approach to the management of cystic fibrosis.
This open access book examines health trajectories and health transitions at different stages of the life course, including childhood, adulthood and later life. It provides findings that assess the role of biological and social transitions on health status over time. The essays examine a wide range of health issues, including the consequences of military service on body mass index, childhood obesity and cardiovascular health, socio-economic inequalities in preventive health care use, depression and anxiety during the child rearing period, health trajectories and transitions in people with cystic fibrosis and oral health over the life course. The book addresses theoretical, empirical and methodological issues as well as examines different national contexts, which help to identify factors of vulnerability and potential resources that support resilience available for specific groups and/or populations. Health reflects the ability of individuals to adapt to their social environment. This book analyzes health as a dynamic experience. It examines how different aspects of individual health unfold over time as a result of aging but also in relation to changing socioeconomic conditions. It also offers readers potential insights into public policies that affect the health status of a population.