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Modern computer-intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. This new edition of the bestselling Randomization, Bootstrap and Monte Carlo Methods in Biology illustrates the value of a number of these methods with an emphasis on biological applications. This textbook focuses on three related areas in computational statistics: randomization, bootstrapping, and Monte Carlo methods of inference. The author emphasizes the sampling approach within randomization testing and confidence intervals. Similar to randomization, the book shows how bootstrapping, or resampling, can be used for confidence intervals and tests of significance. It also explores how to use Monte Carlo methods to test hypotheses and construct confidence intervals. New to the Third Edition Updated information on regression and time series analysis, multivariate methods, survival and growth data as well as software for computational statistics References that reflect recent developments in methodology and computing techniques Additional references on new applications of computer-intensive methods in biology Providing comprehensive coverage of computer-intensive applications while also offering data sets online, Randomization, Bootstrap and Monte Carlo Methods in Biology, Third Edition supplies a solid foundation for the ever-expanding field of statistics and quantitative analysis in biology.
Randomization, Bootstrap and Monte Carlo Methods in Biology, Second Edition features new material on on bootstrap confidence intervals and significance testing, and incorporates new developments on the treatments of randomization methods for regression and analysis variation, including descriptions of applications of these methods in spreadsheet programs such as Lotus and other commercial packages. This second edition illustrates the value of modern computer intensive methods in the solution of a wide range of problems, with particular emphasis on biological applications. Examples given in the text include the controversial topic of whether there is periodicity between co-occurrences of species on islands.
Modern computer-intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. Like its bestselling predecessors, the fourth edition of Randomization, Bootstrap and Monte Carlo Methods in Biology illustrates a large number of statistical methods with an emphasis on biological applications. The focus is now on the use of randomization, bootstrapping, and Monte Carlo methods in constructing confidence intervals and doing tests of significance. The text provides comprehensive coverage of computer-intensive applications, with data sets available online. Features Presents an overview of computer-intensive statistical methods and applications in biology Covers a wide range of methods including bootstrap, Monte Carlo, ANOVA, regression, and Bayesian methods Makes it easy for biologists, researchers, and students to understand the methods used Provides information about computer programs and packages to implement calculations, particularly using R code Includes a large number of real examples from a range of biological disciplines Written in an accessible style, with minimal coverage of theoretical details, this book provides an excellent introduction to computer-intensive statistical methods for biological researchers. It can be used as a course text for graduate students, as well as a reference for researchers from a range of disciplines. The detailed, worked examples of real applications will enable practitioners to apply the methods to their own biological data.
A hands-on guide to using R to carry out key statistical practices in educational and behavioral sciences research Computing has become an essential part of the day-to-day practice of statistical work, broadening the types of questions that can now be addressed by research scientists applying newly derived data analytic techniques. Comparing Groups: Randomization and Bootstrap Methods Using R emphasizes the direct link between scientific research questions and data analysis. Rather than relying on mathematical calculations, this book focus on conceptual explanations and the use of statistical computing in an effort to guide readers through the integration of design, statistical methodology, and computation to answer specific research questions regarding group differences. Utilizing the widely-used, freely accessible R software, the authors introduce a modern approach to promote methods that provide a more complete understanding of statistical concepts. Following an introduction to R, each chapter is driven by a research question, and empirical data analysis is used to provide answers to that question. These examples are data-driven inquiries that promote interaction between statistical methods and ideas and computer application. Computer code and output are interwoven in the book to illustrate exactly how each analysis is carried out and how output is interpreted. Additional topical coverage includes: Data exploration of one variable and multivariate data Comparing two groups and many groups Permutation tests, randomization tests, and the independent samples t-Test Bootstrap tests and bootstrap intervals Interval estimates and effect sizes Throughout the book, the authors incorporate data from real-world research studies as well aschapter problems that provide a platform to perform data analyses. A related Web site features a complete collection of the book's datasets along with the accompanying codebooks and the R script files and commands, allowing readers to reproduce the presented output and plots. Comparing Groups: Randomization and Bootstrap Methods Using R is an excellent book for upper-undergraduate and graduate level courses on statistical methods, particularlyin the educational and behavioral sciences. The book also serves as a valuable resource for researchers who need a practical guide to modern data analytic and computational methods.
Combines recent developments in resampling technology (including the bootstrap) with new methods for multiple testing that are easy to use, convenient to report and widely applicable. Software from SAS Institute is available to execute many of the methods and programming is straightforward for other applications. Explains how to summarize results using adjusted p-values which do not necessitate cumbersome table look-ups. Demonstrates how to incorporate logical constraints among hypotheses, further improving power.
We have written this book as a guide to the design and analysis of field studies of resource selection, concentrating primarily on statistical aspects of the comparison of the use and availability of resources of different types. Our in tended audience is field ecologists in general and wildlife biologists in particular who are attempting to measure the extent to which real animal populations are selective in their choice of food and habitat. As such, we have made no attempt to address those aspects of theoretical ecology that are concerned with how animals might choose their resources if they acted in an optimal manner. The book is based on the concept of a resource selection function, where this is a function of characteristics measured on resource units such that its value for a unit is proportional to the probability of that unit being used. We argue that this concept leads to a unified theory for the analysis and interpretation of data on resource selection and can replace many ad hoc statistical methods that have been used in the past.
Random assignment; Calculating significance values; One-way analysis of variance and the independent t test; Repeated-measures analysis of variance and the correlated t test; Factorial designs; Multivariate designs; Correlation; Trend tests; One-subject randomization tests.
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Helping you become a creative, logical thinker and skillful "simulator," Monte Carlo Simulation for the Pharmaceutical Industry: Concepts, Algorithms, and Case Studies provides broad coverage of the entire drug development process, from drug discovery to preclinical and clinical trial aspects to commercialization. It presents the theories and metho
We developed the first edition of this book because we perceived a need for a compilation on study design with application to studies of the ecology, conser- tion, and management of wildlife. We felt that the need for coverage of study design in one source was strong, and although a few books and monographs existed on some of the topics that we covered, no single work attempted to synthesize the many facets of wildlife study design. We decided to develop this second edition because our original goal – synthesis of study design – remains strong, and because we each gathered a substantial body of new material with which we could update and expand each chapter. Several of us also used the first edition as the basis for workshops and graduate teaching, which provided us with many valuable suggestions from readers on how to improve the text. In particular, Morrison received a detailed review from the graduate s- dents in his “Wildlife Study Design” course at Texas A&M University. We also paid heed to the reviews of the first edition that appeared in the literature.