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After World War II, the US Atomic Energy Commission (AEC) began mass-producing radioisotopes, sending out nearly 64,000 shipments of radioactive materials to scientists and physicians by 1955. Even as the atomic bomb became the focus of Cold War anxiety, radioisotopes represented the government’s efforts to harness the power of the atom for peace—advancing medicine, domestic energy, and foreign relations. In Life Atomic, Angela N. H. Creager tells the story of how these radioisotopes, which were simultaneously scientific tools and political icons, transformed biomedicine and ecology. Government-produced radioisotopes provided physicians with new tools for diagnosis and therapy, specifically cancer therapy, and enabled biologists to trace molecular transformations. Yet the government’s attempt to present radioisotopes as marvelous dividends of the atomic age was undercut in the 1950s by the fallout debates, as scientists and citizens recognized the hazards of low-level radiation. Creager reveals that growing consciousness of the danger of radioactivity did not reduce the demand for radioisotopes at hospitals and laboratories, but it did change their popular representation from a therapeutic agent to an environmental poison. She then demonstrates how, by the late twentieth century, public fear of radioactivity overshadowed any appreciation of the positive consequences of the AEC’s provision of radioisotopes for research and medicine.
Radioisotopes in the Human Body: Physical and Biological Aspects provides a unified presentation of the manner in which radioisotopes are deposited in the human body. This book focuses on bone structure and the irradiation of bone because so many of the available radioisotopes are deposited in bone. Organized into nine chapters, this book begins with an overview of the physical considerations that are significant to the dosimetry of internally deposited radioisotopes. This text then examines the structure and formation of bone in some detail. Other chapters consider the importance of bone in relation to potential radiation damage. This book discusses as well the relationship between radiation dose and radiobiological effects. The final chapter deals with the case of internal irradiation by radioisotopes. This book is a valuable resource for biologists, health physicists, scientists, and students. Radiation protection officers and individuals who have responsibilities for the safe use of radioactive substances will also find this book useful.
Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.
This bibliography contains a total of 959 selected references on the use of radioisotopes in biological research. These references were selected from the scientific literature published during the period 1958-1963. Author, isotope, and report number indexes are included.
This Very Short Introduction is an exciting and non-traditional approach to understanding the terminology, properties, and classification of chemical elements. It traces the history and cultural impact of the elements on humankind from ancient times through today. Packed with anecdotes, The Elements is a highly engaging and entertaining exploration of the fundamental question: what is the world made from?
Radioactive Tracers in Biology: An Introduction to Trace Methodology, Second Edition focuses on the biochemical and physiological aspects of tracer research, including medical applications of tracer techniques, radioactivity, radiation hazards, and radioactive isotopes. The book first offers information on atomic nuclei, radioactivity, and the production of radioactive isotopes and radiation characteristics of tracer atoms. Discussions focus on nuclear reactions, neutron-induced and deuteron-induced transmutations, properties of atomic nuclei, and target techniques and radiochemistry. The manuscript also ponders on the procedures for radioactive assay and radiation hazards. The text examines the biochemical, medical, and physiological applications of tracer methodology. The manuscript also takes a look at radioactive hydrogen, short-lived and long-lived radioactive carbon, radioactive phosphorus and sulfur, and alkali metal and alkaline earth tracers. Topics include synthesis of organic intermediates for tracer carbon studies; biosynthesis of labeled carbon compounds; and general survey of alkali metal tracers. The publication is a dependable reference for readers interested in radioactive tracers.
A solid introduction to stable isotopes that can also be used as an instructive review for more experienced researchers and professionals. The book approaches the use of isotopes from the perspective of ecological and biological research, but its concepts can be applied within other disciplines. A novel, step-by-step spreadsheet modeling approach is also presented for circulating tracers in any ecological system, including any favorite system an ecologist might dream up while sitting at a computer. The author’s humorous and lighthearted style painlessly imparts the principles of isotope ecology. The online material contains color illustrations, spreadsheet models, technical appendices, and problems and answers.
Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.
Provides an introduction to the use of radioactivity in the bioscience laboratory. The text covers general aspects of radioactivity, methods for the detection of radioactivity, radioisotope protocols used to study key cellular processes, and a summary of legislative requirements in the US and European Union. Guidance on safe handling and detailed recipes are provided.