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The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Quercetin is a uniquitous phytochemical and a major flavonoid consumed in the human diet. It is also a part of the active principles of several medicinal plants and is used as a supplement for the treatment of several diseases. The authors of this book discuss the latest advances in quercetin research, its antioxidant properties as well as health benefits.
Quercetin, the most common member of the flavonoids family, is a group of chemical compounds that can be found in the plant kingdom. Fruits and vegetables, particularly citrus fruits, apples, onions, parsley, tea, and red wine, are the primary dietary sources of quercetin. In this book, the authors present topical research in the study of the dietary sources, functions and health benefits of quercetin. Topics discussed include the formulations for pharmaceutical administration of quercetin; the action of quercetin on oxygen uptake by uncoupled mitochondria oxidizing various substrates; the oral health benefits of quercetin; in vitro antibacterial activities and murine studies of novel quercetin diacylglycosyde analogues and the suppressive effect of quercetin on intestinal tight junction permeability.
This book covers all aspects of oxygen delivery to tissue, including blood flow and its regulation as well as oxygen metabolism. Special attention will be paid to methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biochemical basis for pathology related to tissue oxygenation. This book is multidisciplinary and designed to bring together experts and students from a range of research fields including biochemical engineering, physiology, microcirculation, and hematology.
Polyphenols: Mechanisms of Action in Human Health and Disease, Second Edition describes the mechanisms of polyphenol antioxidant activities and their use in disease prevention. Chapters highlight the anti-inflammatory activity of polyphenols on key dendritic cells, how they modulate and suppress inflammation, and how they are inactivated or activated by metabolism in the gut and circulating blood. Polyphenols have proven effective for key health benefits, including bone health, organ health, cardiac and vascular conditions, absorption and metabolism, and cancer and diseases of the immune system. They are a unique group of phytochemicals that are present in all fruits, vegetables and other plant products. This very diverse and multi-functional group of active plant compounds contain powerful antioxidant properties and exhibit remarkable chemical, biological and physiological properties, including cancer prevention and cardio-protective activities. - Expands coverage on green tea, cocoa, wine, cumin and herbs - Outlines their chemical properties, bioavailability and metabolomics - Provides a self-teaching guide to learn the mechanisms of action and health benefits of polyphenols
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Due to changes in the learning and research environment, changes in the behavior of library users, and unique global disruptions such as the COVID-19 pandemic, libraries have had to adapt and evolve to remain up-to-date and responsive to their users. Thus, libraries are adding new, digital resources and services while maintaining most of the old, traditional resources and services. New areas of research and inquiry in the field of library and information science explore the applications of machine learning, artificial intelligence, and other technologies to better serve and expand the library community. The Handbook of Research on Knowledge and Organization Systems in Library and Information Science examines new technologies and systems and their application and adoption within libraries. This handbook provides a global perspective on current and future trends concerning library and information science. Covering topics such as machine learning, library management, ICTs, blockchain technology, social media, and augmented reality, this book is essential for librarians, library directors, library technicians, media specialists, data specialists, catalogers, information resource officers, administrators, IT consultants and specialists, academicians, and students.
Cadmium is widely dispersed in the environment. Human exposure to low levels occur as a result of natural processes as well as human activities such as mining, smelting, fossil fuel combustion and industrial use. Pollution of the general environment by cadmium has as yet only been related to the development of human disease in some special situations, such as itai-itai disease and renal dysfunction in Belgium and in China. However, the possibility of more widespread contamination and greater mobility of cadmium in the environment on the one hand and the advent of new data concerning the carcinogenicity of cadmium on the other, make this review of the "state of the art" in human risk identification and assessment timely. Recent studies on human exposure to cadmium metabolism and toxicology, renal dysfunction and related effects, and experimental and epidemiological evidence for carcinogenicity of cadmium are described.
This book describes quercetin, a naturally occurring plant flavonoid, discussing its occurrence, impact on the body's defenses, and potential applications. Chapters address such topics as quercetin’s role in metabolism, mechanism of action, potential use as a supplement in different forms, and its antiviral, antibacterial, anti-inflammatory, antioxidant, and anticancer qualities.
Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more. - Explores neuronal protection by polyphenol metabolites and their application to medical care - Defines modulation of enzyme actions to help researchers see and study polyphenols' mechanisms of action, leading to clinical applications - Includes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases