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This book provides a quantitative treatment of the science of ecotoxicology. The first chapters consider fundamental concepts and definitions essential to understanding the fate and effects of toxicants at various levels of ecological organization as covered in the remaining chapters. Scientific ecotoxicology and associated topics are defined. The historical perspective, rationale, and characteristics are outlined for the strong inferential and quantitative approach advocated in this book. The general measurement process is discussed, and methodologies for defining and controlling variance, which could otherwise exclude valid conclusions regarding ecotoxicological endeavors, are considered. Ecotoxicological concepts at increasing levels of ecological organization are discussed in the second part of the book. Quantitative methods used to measure toxicant effects are outlined in this section. The final chapter summarizes the book with a brief discussion of ecotoxicological assessment. Numerous figures and tables accompany text, with many statistical tables found in the appendix for quick reference. Although the book primarily focuses on aquatic systems, with appropriate modification the concepts and methods can be applied to terrestrial systems.
Quantitative Ecotoxicology, Second Edition explores models and methods of quantitative ecotoxicology at progressively higher biological scales using worked examples and common software packages. It complements the author’s previous books, Fundamentals of Ecotoxicology, Third Edition and Ecotoxicology: A Comprehensive Treatment. Encouraging a more rigorous inferential approach to research, the book examines the quantitative features of the science of ecotoxicology. The first chapters lay the foundation by introducing fundamental concepts and definitions. The author traces the historical perspective, rationale, and characteristics of scientific ecotoxicology as well as the general measurement process. He also considers methodologies for defining and controlling variance, which could otherwise exclude valid conclusions from ecotoxicological endeavors. The book then discusses ecotoxicological concepts at increasing levels of ecological organization and outlines quantitative methods used to measure toxicant accumulation and effects. Reflecting the importance of establishing type I and type II error rates, it highlights design issues, particularly sample size and power estimation. The final chapter summarizes the book with a brief discussion of ecotoxicology from a nonregulatory perspective. Extensively updated, this second edition has been expanded to include terrestrial as well as aquatic ecotoxicology. Requiring only a basic knowledge of statistics, this highly readable book is suitable for graduate students and researchers as well as practicing environmental scientists and engineers. It guides readers to better understand the fate and effects of toxicants in the biosphere—and helps them frame this understanding in quantitative terms. What’s New in This Edition More than 40 new figures and 20 new worked examples Updated measurement quality methods and software Expanded coverage of synecological models and methods More integration of Bayesian concepts Appendices for power analysis and basic matrix methods Additional mixture toxicity and up-and-down methods Greatly expanded discussion of significance testing Expanded discussion of metapopulations Matrix tools for population demography Light isotope-based models for trophic transfer of toxicants Inclusion of metacommunity and SHE analysis techniques R script examples by Eduard Szöcs (University Koblenz-Landau) available at http://edild.github.io/blog/categories/quantitative-ecotoxicology-with-r/
For the first time, here is a book that focuses on in vitro approaches to the study of the toxicology of polluting agents (including heavy metals, radionuclides, micro-organics, estrogenic compounds, and complex mixtures) in the aquatic environment. The importance of in vitro methods is that they allow standardised techniques to be developed and validated for substance and species specific experiments in a controlled way. Also, they allow mechanistic studies without the problems of individual variation between animals and environmental stress.
Aquatic Ecotoxicology: Advancing Tools for Dealing with Emerging Risks presents a thorough look at recent advances in aquatic ecotoxicology and their application in assessing the risk of well-known and emerging environmental contaminants. This essential reference, brought together by leading experts in the field, guides users through existing and novel approaches to environmental risk assessment, then presenting recent advances in the field of ecotoxicology, including omics-based technologies, biomarkers, and reference species. The book then demonstrates how these advances can be used to design and perform assays to discover the toxicological endpoints of emerging risks within the aquatic environment, such as nanomaterials, personal care products, PFOS and chemical mixtures. The text is an invaluable reference for any scientist who studies the effects of contaminants on organisms that live within aquatic environments. Provides the latest perspectives on emerging toxic risks to aquatic environments, such as nanomaterials, pharmaceuticals, chemical mixtures, and perfluorooctane sulfonate (PFOS) Offers practical guidance on recent advances to help in choosing the most appropriate toxicological assay Presents case studies and information on a variety of reference species to help put the ecotoxicological theory into practical risk assess
An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field. Provides with the latest perspectives on the impacts of toxicants on aquatic environments, such as nanotoxicology, toxicogenomics, ocean acidification and eutrophication Offers a complete overview, beginning with the origins of aquatic toxicology and concluding with potential future challenges Includes guidance on testing methods and a glossary of aquatic toxicology terms
CHEMOMETRICS AND CHEMINFORMATICS IN AQUATIC TOXICOLOGY Explore chemometric and cheminformatic techniques and tools in aquatic toxicology Chemometrics and Cheminformatics in Aquatic Toxicology delivers an exploration of the existing and emerging problems of contamination of the aquatic environment through various metal and organic pollutants, including industrial chemicals, pharmaceuticals, cosmetics, biocides, nanomaterials, pesticides, surfactants, dyes, and more. The book discusses different chemometric and cheminformatic tools for non-experts and their application to the analysis and modeling of toxicity data of chemicals to various aquatic organisms. You’ll learn about a variety of aquatic toxicity databases and chemometric software tools and webservers as well as practical examples of model development, including illustrations. You’ll also find case studies and literature reports to round out your understanding of the subject. Finally, you’ll learn about tools and protocols including machine learning, data mining, and QSAR and ligand-based chemical design methods. Readers will also benefit from the inclusion of: A thorough introduction to chemometric and cheminformatic tools and techniques, including machine learning and data mining An exploration of aquatic toxicity databases, chemometric software tools, and webservers Practical examples and case studies to highlight and illustrate the concepts contained within the book A concise treatment of chemometric and cheminformatic tools and their application to the analysis and modeling of toxicity data Perfect for researchers and students in chemistry and the environmental and pharmaceutical sciences, Chemometrics and Cheminformatics in Aquatic Toxicology will also earn a place in the libraries of professionals in the chemical industry and regulators whose work involves chemometrics.
Completely revised and updated, Fundamentals of Ecotoxicology, Second Edition presents a treatment of ecotoxicology ranging from molecular to global perspectives. The authors focus first on lower levels of organization and then extend their discussion to include landscape, regional, and biospheric topics, imparting a perspective as broad as the the problems facing practicing professionals. See what's new in this edition: A comprehensive chapter on the nature, transport, and fate of major classes of contaminants in terrestrial, freshwater, and marine systems Side bars containing vignettes by leaders in the field let you benefit from the experience of diverse practitioners in the field An appendix covering European environmental regulations The authors detail key contaminants of concern, explore their fate and cycling in the biosphere, and discuss bioaccumulation and the effects of contaminants at increasing levels of ecological organization. They cover regulatory aspects of the field in separate chapters that address the technical issues of risk assessment and discuss key U.S. and European legislation in the appendices. Complete with study questions, a detailed glossary, and vignettes by various experts exploring special topics in ecotoxicology, Fundamentals of Ecotoxicology, Second Edition is an ideal introductory textbook for both undergraduate- and graduate-level courses, as well as a valuable reference for professionals.
Proceedings of the Indo-Dutch Training Course on Aquatic Ecotoxicology, Lucknow, India, 1988
This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.
Research into ecotoxicology can be classified into three fundamental concerns: abiotic factors, which characterize the physicochemistry of environments; biotic factors, relating to biological structures and functions; and contamination factors, which define the modes of pollution of ecosystems. The most significant research methodologies currently being developed in aquatic ecotoxicology are presented, specifically experimental approaches in the laboratory