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This book provides readers up-to-date information on various aspects affecting assisted reproduction laboratories and corresponding management approaches, based on latest literatures, clinical practice, and international consensus. Key points of laboratory environment, laboratory operations and quality control measures are presented in details. Last but not least, ethical issues and countermeasures of assisted reproductive technology are discussed. It will be a practical and reader-friendly resource to help reproductive medicine practitioners establish a disciplined risk and control system for assisted reproduction laboratories and techniques.
This book provides readers up-to-date information on various aspects affecting assisted reproduction laboratories and corresponding management approaches, based on latest literatures, clinical practice, and international consensus. Key points of laboratory environment, laboratory operations and quality control measures are presented in details. Last but not least, ethical issues and countermeasures of assisted reproductive technology are discussed. It will be a practical and reader-friendly resource to help reproductive medicine practitioners establish a disciplined risk and control system for assisted reproduction laboratories and techniques.
In the last decades, major advances have been made in assisted reproductive technologies (ART) and the public demand for these procedures has increased globally. All ART clinics, from those just starting out to the well established, must employ the latest equipment and implement the best practices, while ensuring that their resources are effectively engaged to optimize patient outcomes. This is a tenet of the fiduciary role of physicians and it is increasingly recognized as a quantifiable goal regulated by formal certifications and accreditations. Quality management protocols such as those proposed by the International Organization for Standardization (ISO) are being rapidly adopted as standards of measure. Quality Management in ART Clinics: A Practical Guide provides easily adoptable ways to implement and improve formalized quality management systems. Essential to any clinic to achieve best practices and maintenance of formal regulatory certifications, this book brings together the know-how of experienced opinion leaders operating in key areas worldwide. The book offers an overview of primary regulations in the ART field, with attention to quality management demands, and links specific requirements to practical steps for implementation. Filled with process and procedure examples, flow diagrams and administrative form templates, this book is the first of its kind, gathering the necessary elements for optimizing practice, management, and quality assurance.
Updated edition of this bestselling book, now extended to include quality and risk management in the ART clinic.
With the advent of Assisted Reproductive Technologies, our understanding of the reproductive system in both men and women has progressed in an exponential manner. Along with this increase in knowledge has emerged new and advanced laboratories performing unique techniques aimed at diagnosing and treating infertility problems. And as these laboratories expand, the need for properly trained technicians has also emerged. But while many ART labs are staffed with biologists well trained in reproductive research techniques, they lack the necessary skills to effectively manage these labs. The Handbook of the Assisted Reproduction Laboratory addresses many of the management issues and basic background information on reproductive biology and medicine needed by the technicians staffing and directing these ART labs. Internationally recognized experts in the field discuss various topics in this handbook, which: Reviews male and female reproductive systems and processes Discusses the clinical diagnosis and management of male and female infertility Provides new information on the state-of-the-art techniques of egg and embryo culture, micromanipulation, and biopsy Presents various aspects of quality control, quality assurance, and clinical laboratory management With its in-depth analysis of management issues, as well as basic background information on reproductive biology and medicine, the Handbook of the Assisted Reproduction Laboratory serves as an ideal guide for current investigation and as a stimulus for future developments in the field.
An authoritative account of infertility, covering clinical assessment, management and the delivery and organisation of complex treatments.
Assisted reproduction techniques have led to the birth of 4 million babies worldwide Assisted reproduction techniques (ART), in particular in-vitro fertilization and intra-cytoplasmic sperm injection, are the most advanced forms of infertility treatment. They involve numerous counseling, medical, surgical and laboratory-based steps. At each step various problems and complications could be encountered that challenge even the most experienced ART practitioners. Moreover, patients with complex medical disorders may require ART, presenting further challenges. Assisted Reproduction Techniques will stimulate resourceful thinking in the ART practitioner when faced with these challenges. It outlines various management options, the reasoning behind them, and the evidence on which they are based to enable the practitioner to choose the most suitable solution for the needs of each patient. Written by 122 internationally renowned experts, Assisted Reproduction Techniques follows the patient's journey throughout the whole ART process, with chapters on: Counseling and preparation Ovarian stimulation Oocyte retrieval Embryo transfer The luteal phase The ART laboratory The male patient The ART pregnancy Each of the 100 concise chapters includes clinical cases, background, evidence-based practical management options, preventive measures and key-point summaries of the important details. Assisted Reproduction Techniques gives a wide-ranging practical guide to all those wishing to support couples who cannot conceive naturally.
Practical and effective; this book supports challenging clinical and laboratory issues that the IVF practitioner faces all day, every day.
Whilst assisted reproduction techniques (ART) have become increasingly successful and largely standardized, there is still only a partial understanding of what constitutes a 'true' embryo environment. Replicating the varying physiological conditions of the in-vivo environment that the embryo travels through in the in-vitro culture is still a major challenge in ART. This practical volume details how to organize and operate an IVF laboratory in order to mimic these conditions for successful embryo culture. Environments and equipment that are essential for running safe and efficient facilities such as maintaining good air quality and hygiene protocols, and utilizing an effective layout are covered in detail. Other chapters discuss the different consumables needed, optimal handling techniques and parameter monitoring systems, as well as recent advances in the area including artificial intelligence and automation. This is an indispensable guide to understanding the background science of culturing embryos, crucial to successful outcomes in ART.
Assisted Reproduction is a specialty undergoing rapid change as new technologies are introduced and new research challenges previous treatment options. This text examines a selection of controversial topics for both laboratory and clinical practice and tries to place them in perspective, so readers can understand how and why the current state of the question has come about and how future contributions to the debate should be measured. All physicians involved with the technologies concerned will learn from the expert contributions assembled here. CONTENTS: The use of ovarian markers * Use of molecular markers of endometrial receptivity * Use of GnRHa for triggering final oocyte maturation during ovarian stimulation cycles * Use of time-lapse embryo imaging in assisted reproductive technology practice * Use of cryopreservation for all embryos * Preimplantation genetic screening * The use of single embryo transfer * Use of luteal phase support * Measuring safety and efficiency in in vitro fertilization * To flush follicles during egg collection or not * Use of blastocyst culture * Use of mitochondrial donation * Controversies in recurrent implantation failure: From theory to practice * Fibroids: To remove or not? * Limitations of endometrioma surgery in in vitro fertilization: Possibilities of early disease control