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Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. Puzzling Cases of Epilepsy highlights the importance that original observations have in inspiring both new treatments and continued research. - Presents unique and challenging case vignettes in epilepsy contributed by eminent physicians in the field - Provides practicing physicians with examples of how baffling cases were handled and solved - A new section provides a translational perspective, with basic scientists discussing the potential mechanisms underlying original clinical observations, and clinical scientists discussing the clinical implications of experiments in the epilepsy laboratory
A leading neurologist recounts some of her most astonishing and challenging cases, demonstrating how the study of epilepsy is critical to our understanding of the brain. A “brilliant . . . beautifully humane account” for readers of Oliver Sacks’ The Man Who Mistook His Wife for a Hat (Guardian, Best Books of the Year) Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to solve them: a man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work. In this riveting book, Suzanne O’Sullivan takes you with her as she tracks the clues of her patients’ symptoms. It’s a journey that will open your eyes to the unfathomable intricacies of our brains and the infinite variety of human experience.
From pediatric to the elderly, from contractible to refractive, epilepsy is an illness that manifests in many forms and across a range of demographics. In this fascinating volume, the author details more than one hundred instances where health care practitioners faced unusual challenges in treating the disease. All aspects of epilepsy are explored
Winner of the National Book Critics Circle Award for Nonfiction, this brilliantly reported and beautifully crafted book explores the clash between a medical center in California and a Laotian refugee family over their care of a child.
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
NOW A MAJOR MOTION PICTURE STARRING CHLOË GRACE MORETZ A “captivating” (The New York Times Book Review), award-winning memoir and instant New York Times bestseller that goes far beyond its riveting medical mystery, Brain on Fire is a powerful account of one woman’s struggle to recapture her identity. When twenty-four-year-old Susannah Cahalan woke up alone in a hospital room, strapped to her bed and unable to move or speak, she had no memory of how she’d gotten there. Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled as violent, psychotic, a flight risk. What happened? In an “unforgettable” (Elle), “stunningly brave” (NPR), and breathtaking narrative, Susannah tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that almost didn’t happen. “A fascinating look at the disease that…could have cost this vibrant, vital young woman her life” (People), Brain on Fire is an unforgettable exploration of memory and identity, faith and love, and a profoundly compelling tale of survival and perseverance.
In the summer of 1953, maverick neurosurgeon William Beecher Scoville performed a groundbreaking operation on an epileptic patient named Henry Molaison. But it was a catastrophic failure, leaving Henry unable to create long-term memories. Scoville's grandson, Luke Dittrich, takes us on an astonishing journey through the history of neuroscience, from the first brain surgeries in ancient Egypt to the New England asylum where his grandfather developed a taste for human experimentation. Dittrich's investigation confronts unsettling family secrets and reveals the dark roots of modern neuroscience, raising troubling questions that echo into the present day.
Feed Your Brain Tastier than a twizzler yet more protein-packed than a spinach smoothie, Brain Candy is guaranteed to entertain your brain—even as it reveals hundreds of secrets behind what’s driving that electric noodle inside your skull. These delicious and nutritious pages are packed with bits of bite-sized goodness swiped from the bleeding edge of brain science (including the reason why reading these words is changing your hippocampus at this very moment!) Shelved alongside these succulent neurological nuggets are challenging puzzles and paradoxes, eye-opening perception tests and hacks, fiendish personality quizzes and genius testers, and a grab bag of recurring treats including Eye Hacks, Algebraic Eight Ball, iDread, Wild Kingdom, and Logic of Illogic. Should you look between these covers and inhale the deliciously cherry-flavored scents of knowledge within, you will grow your grey matter while discovering: • Why you should be writing bad poetry • The simple keys to brain training • What trust smells like • The origins of human morality • Why expensive wine always tastes better • The truth about brain sweat • How your diet might be making you dumb • The secrets of game theory • Why economists hate psychology • The mental benefits of coffee and cigarettes • How to really spot a liar • Why you can’t make me eat pie • The benefits of daydreaming • Four simple secrets to persuasion • Why your barin’s fzzuy ligoc alowls you to raed this • How to brainwash friends and family • The science of body language • What pigeons know about art …And much, much more.
This book comprises succinct, accessible clinical cases in neuropsychiatry. Each clinical case has a specific and practical learning point, concerned with assessment, diagnosis, treatment or general approach. Each case models clinical reasoning and shows how the 'puzzle' in the case changed the future practice of the author. Neuropsychiatry Case Studies is divided into sections relating to specific areas of neuropsychiatry, including dementias, movement disorders, autoimmune encephalopathies and epilepsy, amongst others. This book is aimed at trainee doctors in neurology and psychiatry and will also be of interest to fully trained doctors, nurses, psychologists and other allied health professionals working in this area.​
Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments