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Spreading Germs discusses how modern ideas on the bacterial causes of communicable diseases were constructed and spread within the British medical profession in the last third of the nineteenth century. Michael Worboys surveys many existing interpretations of this pivotal moment in modern medicine. He shows that there were many germ theories of disease, and that these were developed and used in different ways across veterinary medicine, surgery, public health and general medicine. The growth of bacteriology is considered in relation to the evolution of medical practice rather than as a separate science of germs.
Vols. for 1951-53 include "Authors" and "Subjects."
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.