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Part of the highly regarded Biopsy Interpretation Series, this fully revised volume is your definitive guide to mastering biopsy pathology interpretation for prostate cancer care. Biopsy Interpretation of the Prostate, 6th Edition, provides superbly illustrated guidance from a top expert in the field, guiding you through the best utilization of H&E microscopy as well as the latest immunohistochemical markers in order to deliver accurate, reliable diagnoses. Hundreds of full-color illustrations depict the full range of benign and malignant prostatic entities.
This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of “atypical” diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. Algorithms, flow charts, and tables are used throughout to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. The book is richly illustrated with carefully selected, high-quality color images and will appeal especially to practicing surgical pathologists as well as pathology residents and fellows in training.
The thoroughly revised Third Edition of this acclaimed reference retains the goal of the original--a practical, state-of-the-art, superbly illustrated guide to prostate biopsy interpretation. Drs. Epstein and Yang, two leading experts, provide comprehensive, current information on the classification, clinical features, prognosis, and evaluation of difficult and unusual as well as common lesions. Coverage includes normal, inflammatory, tumor-like, benign, and malignant conditions. This edition has been updated throughout and contains more tables to aid in differential diagnosis of similar lesions. A bound-in CD-ROM contains more than 1,700 full-color images--all with detailed legends and 100 with checklists of points in favor of and against a cancer diagnosis.
A practical guide for the diagnostic surgical pathologist, this new edition of Biopsy Interpretation of the Breast presents the diverse spectrum of pathologic alterations that occur in the breast in a manner analogous to that in which they are encountered in daily practice. Lesions are grouped together according to their histologic patterns rather than by the traditional benign-malignant categorization in order to simulate the way pathologists face these lesions as they examine microscopic slides on a daily basis. The role of adjunctive studies in solving diagnostic problems in breast pathology is emphasized where appropriate. In addition, the clinical significance and impact on patient management of the various diagnoses are discussed and key clinical and management points highlighted.
Written by three eminent authorities in urologic pathology, this volume is a practical, thorough, and superbly illustrated guide to bladder biopsy interpretation. It begins with normal anatomy and variants of normal histology and then provides comprehensive, current information on all lesions, tumors, and tumor-like lesions. Tables are included to aid in differential diagnosis. Coverage includes the latest World Health Organization and International Society for Urologic Pathology classification system for bladder urothelial neoplasms. A bound-in CD-ROM contains over 800 full-color images covering the entire spectrum of common and rare lesions, and includes a quiz mode that is ideal for board exam preparation.
Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology!
Part of the highly regarded Biopsy Interpretation Series, this fully revised volume provides practical, highly illustrated information on the diagnosis and prognosis of the full range of biopsies of the various tissues of the head and neck region, including the ear. Biopsy Interpretation of the Head and Neck, 3rd Edition, addresses both common and unusual issues that arise in day-to-day practice, with an emphasis on the complex area of the upper aerodigestive tract and ear.
Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
This book highlights the similarities and differences in the pathology of the genital and urinary tracts in males and females.
The Gleason system is the most important prognostic marker of prostate cancer that is critical to patient management and drives therapies across all disciplines dealing with prostate cancer. In addition to an extensive number of photographs, this book discusses in detail clinically related issues that are crucial for the urologist, radiotherapist, and oncologists to know, such as predicting upgrading and downgrading from needle biopsy to radical prostatectomy, risk of Gleason grading change over time, significance of tertiary grade patterns, and prognosis and implications related to various Gleason scores and different therapies. Images that were particularly difficult for contributing pathologists sent in for consultation are used in addition to classic examples, as these cases are the most informative in showing the difficulties with Gleason grading.