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Progress in Pesticide Biochemistry and Toxicology Volume 8 Series Editors D. H. Hutson, Shell Research Ltd, Sittingbourne, UK and T. R. Roberts, Hazleton UK, Harrogate, UK The Mammalian Metabolism of Agrochemicals Edited by D. H. Hutson, Shell Research Ltd, Sittingbourne, UK and G. D. Paulson, US Department of Agriculture, Fargo, USA The Mammalian Metabolism of Agrochemicals is the eighth volume in the Progress in Pesticide Biochemistry and Toxicology series, and collates the various aspects of pesticide metabolism in mammals. The main aims of toxicity and metabolism studies are the assessment of the toxicity of a test compound to man and other mammals, and to evaluate the acceptability of residues which might be found in livestock products for human consumption. The Mammalian Metabolism of Agrochemicals covers the biochemical processes involved in the metabolism of xenobiotics, design of studies to meet current regulatory requirements, the metabolism of herbicides, fungicides and insecticides, factors effecting pesticide metabolism in man and other mammals and examples of natural toxins. This volume provides a comprehensive and extensively referenced source of information, written by leading researchers in this field.
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
Biological Environmental Science is an introductory textbook for undergraduate students who desire a one semester course or, alternatively, a springboard course for advanced environmental offerings. This book features timely issues such as global warming, air, ground and water pollutions, population growth, species extinction and environmental poli
Organic pollutants continue to be a major hazard in the environment. Often difficult to measure accurately and to deal with effectively, these compounds feature more and more prominently in courses on environmental toxicology and environmental sciences. This much needed book is a companion to the highly praised Principles of Ecotoxicology. It covers organic pollutants in greater depth and detail than has been covered in a textbook before. The first part covers issues such as: chemical warfare metababolism of pollutants in animals and plants environmental fate, and effects within ecosystems This is followed by discussion of particular pollutants such as: organochloride insecticides PCBs dioxins organometallic compounds polycyclic aromatic hydrocarbons anticoagulant rodenticides amongst others. The book concludes with coverage of ecotoxicity testing, biomarkers and bioassays and future prospects for improved assessment of the dangers these compounds pose. It breaks new ground in offering a concise source of information on these compounds at a level suitable for senior undergraduates and postgraduates. Professionals working within the fields of environmental toxicology and environmental science will also find it a valuable reference.
Estimating of physicochemical properties: theoretical and experimental approaches. Recommended approaches to assess pesticide mobility in soil. Soils and pesticide mobility. Pesticide leaching models and their use for management purposes. Pesticides in run-off and surface waters. The volatization of pesticide residues. biosensors for detection of pesticides. Techniques and procedures for the determination of pesticides in water.
This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.
History: -- K.D. Watson, P. Wexler, and J. Everitt. -- Highlights in the History of Toxicology. -- Selected References in the History of Toxicology. -- A Historical Perspective of Toxicology Information Systems. -- Books and Special Documents: -- G.L. Kennedy, Jr., P. Wexler, N.S. Selzer, and L.A. Malley. -- General Texts. -- Analytical Toxicology. -- Animals in Research. -- Biomonitoring/Biomarkers. -- Biotechnology. -- Biotoxins. -- Cancer. -- Chemical Compendia. -- Chemical--Cosmetics and Other Consumer. -- Products. -- Chemical--Drugs. -- Chemical--Dust and Fibers. -- Chemical--Metals. -- Chemicals--Pesticides -- Chemicals--Solvents. -- Chemical--Selected Chemicals. -- Clinical Toxicology. -- Developmental and Reproductive Toxicology. -- Environmental Toxicology--General. -- Environmental Toxicology-- Aquatic. -- Environmental Toxicology--Atmospheric. -- Environmental Toxicology--Hazardous Waste. -- Environmental Toxicology--Terrestrial. -- Environmental Toxicology--Wildlife. -- Ep ...
Although chemical pesticides safeguard crops and improve farm productivity, they are increasingly feared for their potentially dangerous residues and their effects on ecosystems. The Future Role of Pesticides explores the role of chemical pesticides in the decade ahead and identifies the most promising opportunities for increasing the benefits and reducing the risks of pesticide use. The committee recommends R&D, program, and policy initiatives for federal agriculture authorities and other stakeholders in the public and private sectors. This book presents clear overviews of key factors in chemical pesticide use, including: Advances in genetic engineering not only of pest-resistant crops but also of pests themselves. Problems in pesticide useâ€"concerns about the health of agricultural workers, the ability of pests to develop resistance, issues of public perception, and more. Impending shifts in agricultureâ€"globalization of the economy, biological "invasions" of organisms, rising sensitivity toward cross-border environmental issues, and other trends. With a model and working examples, this book offers guidance on how to assess various pest control strategies available to today's agriculturist.