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Ten years of research uncover the secret source of growth and profit … Those who center their business on improving people’s lives have a growth rate triple that of competitors and outperform the market by a huge margin. They dominate their categories, create new categories and maximize profit in the long term. Pulling from a unique ten year growth study involving 50,000 brands, Jim Stengel shows how the world's 50 best businesses—as diverse as Method, Red Bull, Lindt, Petrobras, Samsung, Discovery Communications, Visa, Zappos, and Innocent—have a cause and effect relationship between financial performance and their ability to connect with fundamental human emotions, hopes, values and greater purposes. In fact, over the 2000s an investment in these companies—“The Stengel 50”—would have been 400 percent more profitable than an investment in the S&P 500. Grow is based on unprecedented empirical research, inspired (when Stengel was Global Marketing Officer of Procter & Gamble) by a study of companies growing faster than P&G. After leaving P&G in 2008, Stengel designed a new study, in collaboration with global research firm Millward Brown Optimor. This study tracked the connection over a ten year period between financial performance and customer engagement, loyalty and advocacy. Then, in a further investigation of what goes on in the “black box” of the consumer’s mind, Stengel and his team tapped into neuroscience research to look at customer engagement and measure subconscious attitudes to determine whether the top businesses in the Stengel Study were more associated with higher ideals than were others. Grow thus deftly blends timeless truths about human behavior and values into an action framework – how you discover, build, communicate, deliver and evaluate your ideal. Through colorful stories drawn from his fascinating personal experiences and “deep dives” that bring out the true reasons for such successes as the Pampers, HP, Discovery Channel, Jack Daniels and Zappos, Grow unlocks the code for twenty-first century business success.
It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
Offering a study of biological, biomedical and biocultural approaches, this book is suitable for researchers, professors and graduate students across the interdisciplinary area of human development. It is presented in the form of lectures to facilitate student programming.
We tend to associate small town economic development with the decline of the rural United States--empty houses, shuttered shops and rusting factories. A common diagnosis of sluggish small town recovery is their lack of lifestyle amenities that attract new residents and businesses. Yet many small towns have shown progress and potential in recent years. This collection of recent articles by experts presents stories of small-town America's struggle and describes innovations and practices behind successful revivals.
Molecular hydrogen (H2) is an important molecule in the metabolism of diverse microorganisms. It is used either as energy source or for the disposal of reducing equivalents depending on environmental conditions. Furthermore, H2 transmits energy between different species within microbial communities. The enzymes that split or evolve H2 are called hydrogenases and these metalloproteins can be divided into three phylogenetically unrelated classes distinguishable by the metal composition of their active sites, namely [Fe]-, [FeFe]-, and [NiFe]- hydrogenases. Following a century of hydrogenase research, it is now possible to isolate, handle, and investigate these fragile enzymes. There have been numerous advances in understanding the regulation, function, structures, and maturation of these enzymes, as well as their involvement in important processes such as microbial pathogenesis and biogeochemical cycling. The employment of hydrogenases and hydrogenase-based applications could also potentially facilitate the world’s transition to a future sustainable H2-based energy economy.
This Handbook responds to the needs and aspirations of current and future generations of development economists by providing critical reference material alongside or in relation to mainstream propositions. Despite the potential of globalisation in accelerating growth and development in low and middle-income countries through the spread of technology, knowledge and information, its current practice in many parts of the world has led to processes that are socially, economically and politically and ecologically unsustainable. It is critical for development economists to engage with the pivotal question of how to change the nature and course of globalisation to make it work for inclusive and sustainable development. Applying a critical and pluralistic approach, the chapters in this Handbook examine economics of development paths under globalisation, focusing on sustainable development in social, environmental, institutional and political economy dimensions. It aims at advancing the frontier of development economics in these key aspects and generating more refined policy perspectives. It is critically reflective in examining effects of globalisation on development paths to date, and in terms of methodological and analytical approaches, as well as forward-thinking in policy perspectives with a view to laying a foundation for sustainable development.