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This is an open access book. Neuroscience is an emerging branch of science that develops rapidly. It needs neurology, psychiatry, and psychology for us to understand it better. The aim of this conference is to educate and learn the current trends and research in neuroscience education. The 5th International Conference on Neuroscience, Neurology and Psychiatry (ICoNaP) 2022 is a conference held by The Faculty of Medicine of Universitas Sumatera Utara for psychiatrists, neurologists, general practitioners, and other interested specialists; the theme for this year is “Exploring the Neuroscientific Impact of Covid-19”. ICoNAP has been held annually since 2018. The conference invites both national and international speakers from many countries. Throughout these years the committee has invoted various speakers from Malaysia, Singapore, Germany, Australia, India, Thailand, the USA, France, and Malaysia. This year, we invite both national and international speakers from the United Kingdom, Japan, Australia, Singapore, and Malaysia and will be held as a virtual conference.
Cytokines are regulatory polypeptides synthesized by a variety of cells in response to injury, inflammation or infection and which act on different tissues by changing gene expression and cellular metabolism. This book provides the results from recent in vitro studies of the structure and function of various cytokines. It offers an up-to-date overview of the latest advances in cytokine research, including research developments dealing with colony stimulating factors, interferons and growth and differentiation factors - as well as classical hormones such as insulin, neurokinin, somatomedin and parathormones. Several newly identified cytokine receptor structures are also discussed, as are certain activities of the recently discovered 8,000-10,000 m.w. cytokine family.
Two positive regulatory domains have been identified on the IFN-B gene promoter. One of the domains (PRDI) contains the binding site for two nuclear factors termed interferon regulatory factor (IRF)-1 and IRF-2. The second positive regulatory domain (PRDII) comprises a KB-like element. A high degree of homology exists between the IRF-1 and IRF-2 proteins in their N-terminal halves, which comprise the DNA binding domains, but the two factors differ significantly in their C-terminal halves. Some evidence suggested that, unlike IRF-1, IRF-2 acts as a negative regulator of IFN-B transcription.
The book is a collection of high-quality peer-reviewed research papers presented at International Conference on Frontiers of Intelligent Computing: Theory and applications (FICTA 2016) held at School of Computer Engineering, KIIT University, Bhubaneswar, India during 16 – 17 September 2016. The book presents theories, methodologies, new ideas, experiences and applications in all areas of intelligent computing and its applications to various engineering disciplines like computer science, electronics, electrical and mechanical engineering.