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This volume deals with the in vivo activities of these compounds, focusing both on their relevance to normal physiology and their involvement in the pathophysiology of human disease states. The book contains information on cytokines as possible therapeutic agents and describes experimental procedures being explored by clinical researchers in this field. It provides an up-to-date summary of what is now understood about the biological functions of cytokines and anticipates the future directions for research in this area.
Cytokines are regulatory polypeptides synthesized by a variety of cells in response to injury, inflammation or infection and which act on different tissues by changing gene expression and cellular metabolism. This book provides the results from recent in vitro studies of the structure and function of various cytokines. It offers an up-to-date overview of the latest advances in cytokine research, including research developments dealing with colony stimulating factors, interferons and growth and differentiation factors - as well as classical hormones such as insulin, neurokinin, somatomedin and parathormones. Several newly identified cytokine receptor structures are also discussed, as are certain activities of the recently discovered 8,000-10,000 m.w. cytokine family.
Sections 1-2. Keyword Index.--Section 3. Personal author index.--Section 4. Corporate author index.-- Section 5. Contract/grant number index, NTIS order/report number index 1-E.--Section 6. NTIS order/report number index F-Z.
First multi-year cumulation covers six years: 1965-70.
Written by renowned wound care experts Sharon Baranoski and Elizabeth Ayello, in collaboration with an interdisciplinary team of experts, this handbook covers all aspects of wound assessment, treatment, and care.
This book presents a systematic approach to the potential pulmonary complications of various systemic non-pulmonary pediatric disorders. Chapters focus on the pulmonary complications associated with: the major organ systems, types of disorders, metabolic conditions, and various modalities. Although specific diseases will be discussed, the main focus will be on describing the associated organ mechanisms and how they can negatively affect the respiratory system. Each chapter will also discuss methods of prevention, the diagnostic test(s) that may be necessary to diagnose or monitor these complications, and, if applicable, the recommended therapeutic modalities. Pulmonary Complications of Non-Pulmonary Pediatric Disorders provides pulmonologists, pediatricians, and other clinicians with a detailed, reliable explanation of seemingly unrelated signs and symptoms so they can form a more thorough differential diagnosis and prescribe the appropriate diagnostic tests and treatment.