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Phthalate esters are an important class of chemicals widely used in commercial applications, primarily as plasticizers to soften vinyl, but they are also used in consumer products. This book reviews the state of the scientific knowledge of phthalate esters in the environment. Key information reported includes: analytical methodologies; a compilation of concentration measurements in water, sediment, soil, air, dust, and food; plus an assessment of critical exposure pathways. In addition, key physical properties data and fate characteristics that control exposure are reviewed. Also included are pertinent ecotoxicity data and mammalian toxicity and human health information. Finally, the monograph addresses potential environmental risks.
* Offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites] * Examines in vitro cellular aging and the role of immortalization * Presents stages of control of expression and the factors influencing growth and differentiation
Bioassays are among the ecotoxicologist's most effective weapons in the evaluation of water quality and the assessment of ecological impacts of effluents, chemicals, discharges, and emissions on the aquatic environment. Information on these assessment aids is needed throughout the international scientific and environmental management community. This comprehensive reference provides an excellent overview of the small-scale aquatic bioassay techniques and applications currently in use around the world. This special volume is the result of several years of collaboration between Environment Canada and Fisheries and Oceans Canada. Internationally recognized research scientists at many institutions have contributed to this state-of-the-art examination of the exciting, environmentally important field of microscale testing in aquatic toxicology. Microscale Testing in Aquatic Toxicology contains over forty chapters covering relevant principles, new techniques and recent advancements, and applications in scientific research, environmental management, academia, and the private sector.