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The International Symposium on Biopolymers (ISBP) is a successful series of symposia taking place usually every two years since the very first meeting in Toronto 1988. The 18th International Symposium on BioPolymers will take place from September 13-16 2022 and will be held in-person in the oldest city of Switzerland, Sion, and organized by University of Applied Sciences and Arts Western Switzerland (HES-SO) and the University of Stuttgart. This Research Topic will host the proceedings of the conference with selected publications from conference participants. The Research Topic will comprise a collection of scientific publications related to the key elements that are presented at the International Symposium on Biopolymers (ISBP2022), such as metabolic engineering of production strains, production of biobased polymers and their functionalization, biodegradation and recycling of bioplastics, processing of polymers for industrial, agricultural, and medical applications. The goal of this publication is to report the state-of the art and the new developments in this fast-growing field of mainly following classes of biopolymers: Polyesters (poly(hydroxyalkanoates), poly(lactic acid)) , cellulose, pullulan, cyanophycin, polylactic acid (PLA), polyisoprenes (rubbers), but is also open for bio-based polymers like PEF and will include inorganic biopolymers such as polyphosphate (polyP).