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Balanced, readable, and authoritative, this volume provides a well-tested introduction to basic pharmacology for students of medicine, dentistry, pharmacy, and allied health fields. The fourth edition includes new chapters on drug-induced carcinogenesis and teratogenesis, adverse drug reactions, perinatal pharmacology, geriatric pharmacology, and behavioral pharmacology. The material on clincal pharamacology and therapeutics, formerly a separate section, has been integrated into various chapters throughout the text, where it amplifies and illustrates the basic pharamcological concepts. With over 70 chapters, 46 contributors, an improved format and many new illustrations, the new edition provides a lucid, step-by-step introduction to medical pharmacology.
This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. - Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy - Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course - Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study - Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry - Expanded coverage of pharmacogenetics - Expanded coverage of drug transporters and their role in interactions - Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions - A new chapter on drug discovery that focuses on oncologic agents - Inclusion of therapeutic antibodies in chapter on biotechnology products
Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty
**Selected for Doody's Core Titles® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. - Presents the essential knowledge for effective practice of clinical pharmacology - Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology - Offers an extensive regulatory section that addresses US and international issues and guidelines - Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice
This edition includes new case studies, overview chapters on second messenger systems and the nervous and cardiovascular systems, and sections on topics such as drug-resistant TB and pharmacogenetics.
Principles of Medical Pharmacology covers all aspects of medical pharmacology, making it the ideal text for students in pharmacology courses in medicine, biological sciences, pharmacy, and dentistry. The book provides a solid foundation of the principles of pharmacology. Principles are explained through the use of practical examples and case studies. The text covers all aspects of medical pharmacology, including a comprehensive discussion of the clinically important features of pharmacokinetics.This new Seventh Edition has been completely revised and updated to reflect the latest research in the field. Most chapters have been extensively rewritten, with many new authors involved in the preparation of this edition.
Medical Pharmacology & Therapeutics provides all the information medical and healthcare students need throughout their degree programme and beyond, including for professional qualifications such as the PSA. This all-round textbook covers basic pharmacology through to drug prescribing in clinical contexts, covering the pathogenic mechanisms of disease; drug actions, side effects, and the therapeutic principles of drug use. It takes a helpful systems-based approach that orders information according to body systems and disease areas, rather than by drug class. Now in its sixth edition, the book has been fully updated to include latest scientific understanding of drug action and administration and current best practice in prescribing medications, informed by the latest national guidelines. - A clinical focus throughout – suitable for medical, nursing and other healthcare students throughout their training - Thorough update of clinically-relevant medicines to ensure best practice - Information aligned with the British National Formulary (BNF), NICE guidelines and relevant professional benchmarks - Comprehensive drug compendia allow all drugs to be identified and placed within their respective classes - Extensive self-assessment questions to support learning and revision - New to this edition Expanded discussion of the pathophysiology and management of shock - Revised discussion of the management of chronic pain - Consideration of treatment of Covid-19 - Expanded discussion of the pathophysiology and management of shock - Revised discussion of the management of chronic pain - Consideration of treatment of Covid-19
First multi-year cumulation covers six years: 1965-70.