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This classic animal physiology text focuses on comparative examples that illustrate the general principles of physiology at all levels of organisation—from molecular mechanisms to regulated physiological systems to whole organisms in their environment. This textbook is an authoritative and complete guide to the field of animal physiology which uses a threefold approach to teaching. The Comparative Approach emphasises basic mechanisms but allows patterns of physiological function in different species to demonstrate how evolution creates diversity. This approach encourages students to appreciate the underlying principles that govern physiological systems. The Experimental Emphasis helps students to understand the process of scientific discovery and shows how our knowledge of physiology continually increases and finally the Integrative Approach presents information about specific physiological systems at all levels of organisation, from molecular interactions to interactions between an organism and its environment.n included.
All animals face the possibility of food limitation and ultimately starvation-induced mortality. This book summarizes state of the art of starvation biology from the ecological causes of food limitation to the physiological and evolutionary consequences of prolonged fasting. It is written for an audience with an understanding of general principles in animal physiology, yet offers a level of analysis and interpretation that will engage seasoned scientists. Each chapter is written by active researchers in the field of comparative physiology and draws on the primary literature of starvation both in nature and the laboratory. The chapters are organized among broad taxonomic categories, such as protists, arthropods, fishes, reptiles, birds, and flying, aquatic, and terrestrial mammals including humans; particularly well-studied animal models, e.g. endotherms are further organized by experimental approaches, such as analyses of blood metabolites, stable isotopes, thermobiology, and modeling of body composition.
This book describes a novel and unique approach to the treatment of human diseases based on the study of natural animal models. A natural animal model is defined as an animal group or species that possesses a set of biochemical/physiological characteristics which are natural and adaptive for that animal, but are quite abnormal for humans. For example, how is it that birds can tolerate blood glucose concentrations which in humans are associated with diabetes. The natural animal model is living proof that a biological answer to this question is available. By studying natural animal models, we can gain valuable insights into the treatment of various human clinical disorders. Covering a wide range of disorders, this book describes in detail how medical scientists can take advantage of all the “research” that nature has already performed over billions of years in biological problem solving through extensive animal design testing and selection./a