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The authors have provided an overview of the relationships between hormones that are physiologic constituents of the body as well as their pharmacologic use in replacement therapies and related endocrine dys function. Principles of Endocrine Pharmacology concerns itself with the ther apeutic use of hormones, and hormone like substances, or drugs that can act either by suppressing or enhancing the metabolism of certain glands of internal secretion. Other drugs used for nonendocrine ther apies can likewise affect the endocrine system. Endocrine pharmacology emerged in the early 1900s with the use of crude pituitary extracts. By the mid-1900s several investigators had isolated and begun to synthesize hormones or hormonelike substances. Recognizing the limited supply of hormones that could be obtained both from animal sources and human autopsy material, the search for so called hormone substitutes also began early in the 1900s. Recently, re combinant DNA technologies have been used to provide alternative therapeutic sources of human insulin and human growth hormone. Aside from insulin, perhaps no other use of hormonally-active sub stance is better exemplified by those drugs which affect fertility. The synthesis of an orally-effective steroid represented one of the first major breakthroughs in the chemical suppression of ovulation. Since the orally active 19-norsteroids were introduced in the 1950s, several oral contra ceptive steroid preparations have been marketed. Indeed, the advent of oral contraceptives for birth control has led to a renewed interest in endocrine pharmacology.
Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty
Get the BIG PICTURE of Medical Physiology -- and focus on what you really need to know to ace the course and board exams! 4-Star Doody's Review! "This excellent, no-frills approach to physiology concepts is designed to help medical students and other health professions students review the basic concepts associated with physiology for the medical profession. The information is concise, accurate and timely." If you don't have unlimited study time Medical Physiology: The Big Picture is exactly what you need! With an emphasis on what you “need to know” versus “what's nice to know,” and enhanced with 450 full-color illustrations, it offers a focused, streamlined overview of medical physiology. You'll find a succinct, user-friendly presentation designed to make even the most complex concepts understandable in a short amount of time. With just the right balance of information to give you the edge at exam time, this unique combination text and atlas features: A “Big Picture” perspective on precisely what you must know to ace your course work and board exams Coverage of all the essential areas of Physiology, including General, Neurophysiology, Blood, Cardiovascular, Pulmonary, Renal and Acid Base, Gastrointestinal, and Reproductive 450 labeled and explained full-color illustrations 190 board exam-style questions and answers -- including a complete practice test at the end of the book Special icon highlights important clinical information
Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.
A full-color guide to the entire field of clinical endocrinology and its scientific underpinnings – updated with the latest breakthroughs and developments A Doody’s Core Title for 2021! Greenspan’s Basic & Clinical Endocrinology delivers a succinct, leading-edge overview of the underlying molecular biology of the endocrine system and the latest perspectives on the diagnosis and treatment of specific diseases and disorders. Featuring an enhanced design that includes hundreds of full-color illustrations and clinical photographs, Greenspan’s is a true must-have during traditional or integrated courses in endocrinology, endocrinology rotation, or exam prep in internal medicine and endocrinology and as reference for disease management. Greenspan’s provides clinically relevant coverage of metabolic bone disease, pancreatic hormones and diabetes mellitus, hypoglycemia, obesity, geriatric endocrinology, and many other diseases and disorders. Supporting this essential material is a handy appendix of normal hormone reference ranges across the lifespan. Here’s why Greenspan’s is an essential tool for learning how to manage endocrine patients: • The Tenth Edition is enhanced by updated content throughout each chapter • NEW CHAPTERS on Transgender Endocrinology and Disorders of Sexual Determination and Differentiation • Important chapter on Evidence-Based Endocrinology and Clinical Epidemiology • Concise, balanced coverage of both scientific and clinical principles that guide patient management • The best source for current concepts in endocrine pathophysiology to aid clinical decision making • The most practical, current insights into diagnostic testing • More than 270 full-color illustrations and clinical photographs If you are in need of a well-illustrated, completely up-to-date guide to the entire field of clinical endocrinology, this trusted classic belongs on your desk or computer.
A time-saving, stress-reducing approach to learning the essential concepts of pharmacology Great for USMLE review! "This could be a very useful tool for students who struggle with understanding the most basic concepts in pharmacology for course and licensure examinations. 3 Stars."--Doody's Review Service Basic Concepts in Pharmacology provides you with a complete framework for studying -– and understanding -- the fundamental principles of drug actions. With this unique learning system, you’ll be able to identify must-know material, recognize your strengths and weaknesses, minimize memorization, streamline your study, and build your confidence. Basic Concepts in Pharmacology presents drugs by class, details exactly what you need to know about each class, and reinforces key concepts and definitions. With this innovative text you’ll be able to: Recognize the concepts you truly must know before moving on to other material Understand the fundamental principles of drug actions Organize and condense the drug information you must remember Review key information, which is presented in boxes, illustrations, and tables Identify the most important drugs in each drug class Seven sections specifically designed to simplify the learning process and help you gain an understanding of the most important concepts: General Principles Drugs That Affect the Autonomic Nervous System Drugs That Affect the Cardiovascular System Drugs That Act on the Central Nervous System Chemotherapeutic Agents Drugs That Affect the Endocrine System Miscellaneous Drugs (Includes Toxicology and Poisoning)
A volume in the Contemporary Perspectives In Rehabilitation Series, edited by Steven L. Wolf, PhD, PT, FAPTA. Rely on the completely revised and thoroughly updated 4th Edition of this innovative textbook to insure that your students will be able to master this complex content with ease. Organized by body system, each chapter begins with a description of the drug...followed by an explanation of the conditions it treats...and ends with a discussion of how the drug affects physical therapy and how physical therapy may impact drug effectiveness. Dr. Ciccone's easy-to-understand writing style demystifies the science and practice of pharmacology.
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
Market: First Year Medical students, Nurse Practitioner students, and Physician Assistant students Topics covered will be tested on USMLE Step I Each chapter includes self-study questions, learning objectives, and clinical examples Two important areas have been updated: the first pertains to hormonal regulation of bone metabolism and the second to hormonal aspects of obesity and metabolic syndrome
Clinical Small Animal Internal Medicine is a comprehensive, practical reference designed to meet the needs of veterinary practitioners and students alike. Covering all aspects of small animal internal medicine, this innovative guide provides clinically relevant material, plus podcasts and continual updates online. Concise, identically-formatted chapters allow readers to quickly find the most essential information for clinical veterinary practice. Contributions from academic and clinical experts cover general medicine subjects, including patient evaluation and management, critical care medicine, preventative care, and diagnostic and therapeutic considerations. Topics relevant to daily clinical practice are examined in detail, ranging from endocrine, cardiovascular, respiratory, and infectious disease to oncology, dermatology, metabolic orthopedic disease, gastroenterology, and hepatology. A companion website features podcasts and updated information. An important addition to the library of any practice, this clinically-oriented text: Presents complete, practical information on small animal internal medicine Provides the background physiology required to understand normal versus abnormal in real-world clinical settings Includes general medicine topics not covered in other internal medicine books Focuses on information that is directly applicable to daily practice Features podcasts and continual updates on a companion website Carefully tailored for the needs of small animal practitioners and veterinary students, Clinical Small Animal Internal Medicine is an invaluable, reader-friendly reference on internal medicine of the dog and cat.