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This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.
On November 6, 1995, the Institute of Medicine's Vaccine Safety Forum convened a workshop on detecting and responding to adverse events following vaccination. Workshop speakers and participants discussed the difficulties in detecting adverse events, current adverse events detection and response methods and procedures, suggestions for improving the means of detecting and responding to adverse events following vaccination, and future areas of research. This document represents a summary of that workshop.
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
INTERNATIONAL BESTSELLER From renowned mental health expert and speaker Dr. Gabor Maté, this acclaimed, bestselling guide provides insight into the mind-body link between illness and health, and the critical role that stress and our emotional makeup play in an array of common diseases. In this accessible and groundbreaking book—filled with the moving stories of real people—medical doctor and bestselling author Gabor Maté shows that emotion and psychological stress play a powerful role in the onset of chronic illness, including breast cancer, prostate cancer, multiple sclerosis, Alzheimer's disease and many others. An international bestseller translated into over thirty languages, When the Body Says No promotes learning and healing, providing transformative insights into how illlness can be the body's way of saying no to what the mind cannot or will not acknowledge. With great compassion and erudition, Dr. Maté demystifies medical science and empowers us all to be our own health advocates.
"This book identifies the cause and the cure for: Chronic Fatigue Syndrome, Fibromyalgia, Lupus, Sjögren's, Rheumatoid Arthritis, Raynaud's, Rosacea, Myasthenia Gravis, Hashimoto's, Type 2 Diabetes, Multiple Sclerosis and more."
This book brings together articles on the overarching theme of how the environment shapes the immune system. The immune system is commonly assumed to respond to harmful pathogens such as bacteria and viruses. However, harmless bacteria, chemicals, stress, normal food and other factors can also trigger, shape or interfere with the immune system, often producing adverse effects. Yet, it is also becoming increasingly accepted that some of these interactions are physiological and necessary for a healthy immune system. Examples of negative effects include the immunosuppressive effects of UV irradiation, or the immunotoxic effects of man-made chemicals such as polycyclic aromatic hydrocarbons. Autoimmunity or allergies can be the adverse consequences of interaction between the immune system and chemical compounds such as drugs. Positive effects can come from natural exposure levels to bacteria, healthy life-style or the diet. There is a great need to understand how communication between the environment and the immune system works. This book addresses this need. It covers environmental factors (such as bacteria, sun exposure), human factors (such as age, exercise or stress), and important man-made factors (such as air pollution). A chapter on human rights complements the scientific chapters. The book is intended for immunologists, toxicologists and researchers who want to know how the immune system works and is triggered, as well as for medical doctors in environmental medicine and the general public interested in immunology.
Reverse your negative health trajectory and start the journey towards healing and resilient health with Palmer Kippola’s groundbreaking plan to erase the effects of autoimmune disease. “An empowering and actionable guidebook that simplifies the steps back to health. Highly recommended!” —Izabella Wentz, PharmD, FASCP and #1 New York Times bestselling author of Hashimoto's Protocol Palmer Kippola is on a mission to make autoimmune disease history. When she was diagnosed with Multiple Sclerosis at age 19, she began a journey toward healing that resulted in a complete reversal of her symptoms. Now, with the help of leading medical experts, including renowned specialists in immunology and longevity from UCLA and Stanford medical schools, as well as leading practitioners in the field of autoimmunity and functional medicine, Kippola wants to help you find freedom from disease too. This comprehensive book is the first to explore all six of the critical lifestyle factors that are the root causes of autoimmune conditions—and the sources of regaining health: * Discover the foods that can trigger disease as well as healthy solutions to fit your personal nutritional profile *Explore the impact of common, often-undiagnosed infections and ways to optimize your immunity naturally *Learn how gut health is the key to recovery *Gain insight on how hormone imbalances can disrupt healing and how to assess your hormone levels *Eliminate environmental toxins in your home and body, and learn how to live a detox lifestyle *Reduce stress and build resilience Drawing on her own inspiring return to resilient health, as well as the healing stories of a dozen medical doctors and practitioners, plus years of research with autoimmune experts, Palmer Kippola gives readers the tools to beat autoimmune disease—and the hope that relief and healing are possible. “An excellent resource for those who want to use an integrative and functional medicine approach to support their healing journey!” —Terry Wahls, MD, author of The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles
Do you have crud in the blood? Millions of people suffer from autoimmunity whether they know it or not. The root cause of most weight gain, brain and mood problems, and fatigue, autoimmunity can take years--or even decades--for symptoms and a clear diagnosis to arise. Through years of research, Dr. Tom O’Bryan has discovered that autoimmunity is actually a spectrum, and many people experiencing general malaise are already on it. And while autoimmune diseases, such as Alzheimer’s, Multiple Sclerosis, osteoporosis, diabetes, and lupus, have become the third leading cause of death behind heart disease and cancer, many people affected are left in the dark. The good news is that many autoimmune conditions can be reversed through a targeted protocol designed to heal the autoimmune system, 70 percent of which is located in the gut. The Autoimmune Fix includes two comprehensive 3-week plans: In the first 3 weeks, you’ll follow a Paleo-inspired diet during which you cut out gluten, sweets, and dairy--the three primary culprits behind autoimmunity. Once the dietary changes have been addressed, The Autoimmune Fix focuses on the other causes of autoimmunity such as genetics, other dietary issues, and microbiome. The Autoimmune Fix provides a practical and much-needed guide to navigating these increasingly common conditions to help you feel better and develop a plan that works for you.
The way autoimmune disease is viewed and treated is undergoing a major change as an estimated 50 million Americans (and growing) suffer from these conditions. For many patients, the key to true wellness is in holistic treatment, although they might not know how to begin their journey to total recovery. The Autoimmune Wellness Handbook, from Mickey Trescott and Angie Alt of Autoimmune-Paleo.com, is a comprehensive guide to living healthfully with autoimmune disease. While conventional medicine is limited to medication or even surgical fixes, Trescott and Alt introduce a complementary solution that focuses on seven key steps to recovery: inform, collaborate, nourish, rest, breathe, move, and connect. Each step demystifies the process to reclaim total mind and body health. With five autoimmune conditions between them, Trescott and Alt have achieved astounding results using the premises laid out in the book. The Autoimmune Wellness Handbook goes well beyond nutrition and provides the missing link so that you can get back to living a vibrant, healthy life.