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Practical Hepatic Pathology—a new volume in the new Pattern Recognition series—offers you a practical guide to diagnosing every challenging liver biopsy that you encounter in your daily practice. Dr. Romil Saxena presents diagnoses according to a pattern-based organization that guides you from a histological pattern of injury, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Lavish, full-color images capture key hepatic pathology patterns of injury, pathognomonic features and common variations of all major liver diseases and hepatic neoplasms. No other single source delivers the practical, hands-on information you need to solve even the toughest diagnostic challenges in liver biopsies. Recognize the basic patterns of liver injury through an algorithmic approach and establish diagnosis by a pattern-based visual index present at the beginning of the book. Evaluate and interpret biopsy samples using superb, high-quality, full-color images that illustrate pathognomonic features and common variations. Get comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules including clinical features, laboratory tests, imaging findings and differential diagnosis. Understand the pathology and practice of liver transplantation with coverage of the clinical aspects of this procedure.
Part of the new Pattern-Based Approach series, designed to teach pathology in a way that reflects actual sign-out, this new visually-oriented guidebook presents real-life cases and practical diagnostic tips. Disease processes are organized into ‘patterns’ of injury—the method by which pathologists approach their work—and self-assessment quizzes are provided for each chapter to give you experience with high-yield, board-style teaching topics.
Since its first publication more than 35 years ago, MacSween’s Pathology of the Liver, by Drs. Alastair D. Burt, Linda D. Ferrell, and Stefan G. Hübscher, has established itself as the definitive reference on liver pathology. The 7th Edition continues the tradition of excellence with more than 1,000 high-quality illustrations, coverage of the new and emerging diagnostic applications and techniques that pathologists must be familiar with, an up-to-date review of drug-induced injury, and much more. A must-have for every surgical pathologist, MacSween’s remains the most authoritative and comprehensive book in its field. Provides comprehensive, state-of-the-art coverage of all malignant and benign hepatobiliary disorders from an international "who’s who" in the field. Helps you quickly recognize the wide variety of liver appearances that result from infections, tumors, and tumor-like lesions, as well as organ damage caused by drugs and toxins. Features 1,000+ full-color illustrations that provide a complete visual guide to each tumor or tumor-like lesion and assist in the recognition and diagnosis of any tissue sample you’re likely to encounter. Incorporates relevant data from ancillary techniques (immunohistochemistry, cytogenetics, and molecular genetics), giving you the tools required to master the latest breakthroughs in diagnostic technology. Includes an updated chapter on mechanisms of liver disease, including coverage of regression and remodeling of disease and new information on next generation sequencing; an up-to-date review of drug-induced injury, including the effects of herbal and alternative medicines. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
For the surgical pathologist, this coverage of Liver Pathology presents practical information with ample discussion of differential diagnosis and use of special studies, where relevant, to engage pathologists in what you can do daily in practice. Topics include: Steatohepatitis: Histopathologic diagnosis; Regression and subclassification of cirrhosis; Autoimmune hepatitis and overlap syndrome; Liver transplant pathology: challenging diagnostic situations; Hepatocellular adenoma; Immunohistochemistry for the diagnosis of hepatocellular carcinoma; Histologic subtypes of hepatocellular carcinoma: diagnostics and clinical significance; Pediatric cholestatic disorders. Sanjay Kakar and Dhanpat Jain bring their expertise in liver pathology and lead a group of authors whose focus is on liver and GI pathology. The surgical pathologist has at hand in this issue the essential and most current aspects of liver pathology required for daily practice.
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic and nonneoplastic diseases of the digestive tract and accessory organs such as the pancreas and liver, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, Diagnostic Pathology: Hepatobiliary and Pancreas is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls. Features thorough updates throughout, including novel immunohistochemical markers and other ancillary techniques (such as BAP1, INSM1, Rb, albumin in situ hybridization) that play an increasingly critical role in improving diagnoses Addresses recent advances in molecular pathology—new diagnostic, immunohistochemical, molecular, and genetic techniques used for diagnosis, as well as new details about the genesis and activity of tumors in the liver, pancreas, and biliary systems Includes details from the 2019 WHO Classification of Tumors of the Digestive System regarding important changes to diagnostic techniques, identification of new variants of cancers, and immunohistochemical markers and ancillary techniques that improve diagnosis and treatment options Reflects recent WHO updates and updates from the AJCC’s 8th Edition Cancer Staging Manual such as new terminology, new grading of neuroendocrine tumors and neuroendocrine carcinomas, and characteristic molecular alterations in hepatocellular adenoma, cholangiocarcinoma, and other tumors Uses a templated page layout, bulleted text, and a generous number of high-quality images to help practicing and in-training pathologists reach a confident diagnosis
In this issue, guest editors bring their considerable expertise to this important topic. Contains 13 relevant, practice-oriented topics including PSC, small duct PSC, IgG4 and ischemic cholangiopathy: what do you see on needle biopsy?; evolving understanding of noncirrhotic portal hypertension; practical guide, challenges, and pitfalls in liver fibrosis staging; liver pathology after hematopoietic stem cell transplant; medical Liver injury related to cancer treatment; and more. Provides in-depth clinical reviews on liver pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological patterns. Atlas of Liver Pathology considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information. Authored by nationally and internationally recognized pathologists, Atlas of Liver Pathology is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases.
For the surgical pathologist, this coverage of Liver Pathology presents practical information with ample discussion of differential diagnosis and use of special studies, where relevant, to engage pathologists in what you can do daily in practice. Topics include: Steatohepatitis: Histopathologic diagnosis; Regression and subclassification of cirrhosis; Autoimmune hepatitis and overlap syndrome; Liver transplant pathology: challenging diagnostic situations; Hepatocellular adenoma; Immunohistochemistry for the diagnosis of hepatocellular carcinoma; Histologic subtypes of hepatocellular carcinoma: diagnostics and clinical significance; Pediatric cholestatic disorders. Sanjay Kakar and Dhanpat Jain bring their expertise in liver pathology and lead a group of authors whose focus is on liver and GI pathology. The surgical pathologist has at hand in this issue the essential and most current aspects of liver pathology required for daily practice.
This text provides a practical guide for the diagnostic surgical pathologist in evaluating tumors involving the liver. It comprehensively covers the histological findings and key clinical and molecular correlates of liver tumors. The focus is on material that is most relevant to the actual practice of liver pathology including those aspects that are directly relevant to the diagnosis, subtyping and prognostication of hepatic adenomas specimens, including biopsy specimens and surgical resections. The book will teach pathologists how to avoid common diagnostic pitfalls. Each chapter uses or discusses the nomenclature and classification system of liver tumors as per the current WHO classification of liver tumors. Each chapter fully incorporates the most up to date diagnostic methodologies, including immunohistochemistry and molecular methods. Referencing is succinct and references were carefully chosen for their key role as the primary sources of information on a given disease. The text is richly illustrated with beautiful color images that highlight not just the “average” histological findings for a given entity, but also fully illustrate all of the key histological variability. Gross images are also included to highlight important diagnostic features. Tables are used judiciously to present summary information that allows a quick review on how similar entities compare and contrast. In addition, the clinical significance of various diseases will be discussed in a focused fashion that highlights how pathology information is being used to make key clinical management decisions. Each chapter is written by experts in hepatopathology, all from the Mayo Clinic Departments of Pathology. Surgical Pathology of Liver Tumors will be of great utility to surgical pathologists and surgical pathologists in training as well as clinicians involved in the care of patients with liver tumors, particularly hepatologists and oncologists.
"The Pattern-Based Approach series is dedicated to providing pathology textbooks that more closely reflect the challenges of daily sign-out than conventional texts do. In other words, the focus is on practical clinical and histological findings that you actually need to know. This stands in contrast to books dedicated to comprehensive coverage, for which the goal is to provide all information about an entity, much of which is interesting, much of which is not, and most of which is not that important in getting your case signed out properly. That is not to mean that this book covers only common entities because it does not neglect the rare entities either. Instead, the focus is always on practical findings that are good to know, including clinical, histological, and molecular findings, but with an emphasis on histology. For this reason, there are lots of images (790), succinct text, and organizational tools as outlined below that make the book even easier to navigate. Liver pathology can be very challenging and a pattern-based approach is the perfect starting point for providing excellent patient care. This book is not perfect, as few books are, but I hope you like it and find it useful, especially when you are working on actual clinical material. In the end, I believe that there is no greater calling for a textbook than to be considered practical and useful by those who have it in their offices. "--Provided by publisher