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Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.
Due to the increasing trend of international interest in education for climate change and the environment, there has been an increase of research in the area. There is a current question on what the best methods and tools are for integrating climate change education and sustainability into school programs. These educational methods can create the development of effective responses, attitudes, and behaviors to adapt to climate change. Empirical and conceptual models must be explored to help those interested in learning and teaching environmental education and climate change and adding it to modern school curriculum. The Handbook of Research on Environmental Education Strategies for Addressing Climate Change and Sustainability produces innovative approaches, methods, and ideas in education for climate change, environment strategies, and sustainability along with the development of curriculum and strategies for sustainable development goals. The chapters encompass multiple disciplines such as geology, geography, remote sensing, geographic information systems, environmental science, and environmental engineering. This book is ideal for in-service and preservice teachers, administrators, teacher educators, practitioners, stakeholders, researchers, academicians, and students interested in educational strategies and curriculum for climate change and sustainability.
This book is a compilation of scientific knowledge regarding the clinical entity known as “Renal Tubular Acidosis in Children” (RTA). It contains the information needed to comprehend the intricate mechanisms of acid-base metabolism, electrolyte imbalance, and complications related to renal tubular acidosis in the pediatric age group, since the acid-base physiology and the clinical disorders associated with it in children are quite different from the adult counterpart. The chapters, written by authors, experts in the field, describe systemic and renal physiology, electrolyte alterations, as well as the pathogenesis and chromosomal mutations leading to the development of RTA. The reader will find the latest information on diagnostic tools and learn how to approach diagnosis, avoiding improper treatment, rickets, nephrocalcinosis, and renal failure. In addition, new insights on classification, the clinical presentation of each type of RTA, molecular biology, and transmembrane protein transporters are covered. This work is primarily directed at pediatric nephrologists and pediatricians. Nevertheless, general practitioners, medical students, residents and fellows at different medical training programs, and other health care professionals of nutrition, growth and development, gastroenterology and endocrinology may surely benefit from it.
Heavy Metals in the Environment: Impact, Assessment, and Remediation synthesizes both fundamental concepts of heavy metal pollutants and state-of-the-art techniques and technologies for assessment and remediation. The book discusses the sources, origin and health risk assessment of heavy metals as well as the application of GIS, remote sensing and multivariate techniques in the assessment of heavy metals. The various contamination indices like contamination factor, geoaccumulation index, enrichment factor, and pollution index ecological risk index are also included to provide further context on the state of heavy metals in the environment. Covering a variety of approaches, techniques, and scenarios, this book is a key resource for environmental scientists and policymakers working to address environmental pollutants. - Covers state-of-the-art techniques for the assessment and remediation of heavy metals - Presents the interdisciplinary impacts of heavy metals, including human health, ecosystems and water quality - Includes various contamination indices, such as contamination factor, geoaccumulation index, enrichment factor, pollution index and ecological risk index
Algae Biotechnology: Integrated Algal Engineering for Bioenergy, Bioremediation, and Biomedical Applications covers key applications of algae for bioenergy and how to integrate the production of biofuels with environmental, nutraceutical and biomedical processes and products. The book emphasizes cost-effective biofuels production through integrated biorefinery, combining continuous processes and various algae as feedstock to produce biofuel, bioenergy and various high value biochemicals. Novel algal culturing technologies and bioprocess engineering techniques are provided for the optimization of operational approaches for commercial-scale production, as well as to reduce the overall costs. New and existing molecular methods for genetic and metabolic engineering of algae are also presented. Furthermore, methods for the optimization of existing biochemical pathways are explained, and new pathways are introduced, in order to maximize the potential for biofuels production and related nutraceutical and biomedical co-products. This book provides an ideal roadmap for bioenergy researchers and engineers who want to incorporate valuable nutraceutical and biomedical products and environmental practices into the production of biofuels. - Addresses issues faced by the bioenergy sector and how to resolve them through the integration of algal biotechnology and engineering - Provides a guide to the efficient and cost-effective production of bioenergy, while simultaneously mitigating pollution and producing valuable nutraceutical and biomedical biproducts - Covers new and emerging approaches in integrated algal biotechnology - Offers a roadmap to their application in the production of biofuels alongside nutraceutical, biomedical, and environmental processes and products
Comprehensive resource detailing the molecular mechanisms underlying heavy metal toxicity and tolerance in plants Heavy Metal Toxicity and Tolerance in Plants provides a comprehensive overview of the physiological, biochemical, and molecular basis of heavy metal tolerance and functional omics that allow for a deeper understanding of using heavy metal tolerance for deliberate manipulation of plants. Through the authors’ unique approach, the text enables researchers to develop strategies to enhance metal toxicity and deficiency tolerance as well as crop productivity under stressful conditions, in order to better utilize natural resources to ensure future food security. The text presents the basic knowledge of plant heavy metal/metalloid tolerance using modern approaches, including omics, nanotechnology, and genetic manipulation, and covers molecular breeding, genetic engineering, and approaches for high yield and quality under metal toxicity or deficiency stress conditions. With a collection of 26 chapters contributed by the leading experts in the fields surrounding heavy metal and metalloids toxicity and tolerance in crop plants, Heavy Metal Toxicity and Tolerance in Plants includes further information on: Advanced techniques in omics research in relation to heavy metals/metalloids toxicity and tolerance Heavy metals/metalloids in food crops and their implications for human health Molecular mechanisms of heavy metals/metalloids toxicity and tolerance in plants Molecular breeding approaches for reducing heavy metals load in the edible plant parts Hormonal regulation of heavy metals toxicity and tolerance Applications of nanotechnology for improving heavy metals stress tolerance Genetic engineering for heavy metals/metalloids stress tolerance in plants With comprehensive coverage of the subject, Heavy Metal Toxicity and Tolerance in Plants is an essential reference for researchers working on developing plants tolerant to metals/metalloids stress and effective strategies for reducing the risk of health hazards.
Ward off life-threatening disease and symptoms of aging with this guide to boosting your levels of glutathione (GSH), the "master antioxidant." The body has a remarkable ability to ward off disease and heal itself--and it does it with the help of the most important antioxidant you've never heard of: glutathione (GSH), the "master antioxidant." This indispensable molecule--which we make ourselves--holds the key to immunity, vitality, and lifelong health, helping to flush out toxins, fight DNA-damaging free radicals, and rebuild other essential antioxidants like Vitamins C and E. It's been linked to longevity in centenarians, and it protects against diseases like cancer, diabetes, and Alzheimer's. It plays a role in lesser ailments too: low glutathione levels could be the culprit behind your fatigue, aches, and pains. At the forefront of the latest GSH research, Dr. Nayan Patel shares all the information you need to boost your glutathione levels, revitalize your body, and transform your life with this naturally-occurring super antioxidant. In The Glutathione Revolution, he addresses the most important questions about GSH: What exactly is glutathione? What happens when your GSH levels are low? What diseases does GSH ward off? How can you naturally increase the amount of GSH your cells produce? What foods should you eat--and not eat? What are the safest and most effective GSH supplements? With a wealth of practical information and three easy, accessible action plans that you can tailor to your own life and health concerns, you too can harness the power of glutathione.
The world faces significant challenges as the population and consumption continue to grow while nonrenewable fossil fuels and other raw materials are depleted at ever-increasing rates. This informative volume provides a technical approach to address these issues using green design and analysis. It takes an interdisciplinary look at concepts that can be applied across engineering disciplines in the development of products, processes, and systems to minimize environmental impacts across all life cycle phases. Topics include polymers for pollutant removal, wood-based biopolymers, bio-based polymers for drug formulations, biomaterial-based medical implants, biodegradabilty of biopolymer materials, bio-based polymers for food packaging applications, biodegradable polymers for tissue engineering applications, and more.