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This book discusses the history, physics, fundamental principles, sensing technologies, and characterization of plasmonic phenomenon-based fiber-optic biosensors, using optic-plasmonic sensors as a case study. It describes the plasmonic phenomenon and its application in optical fiber-based sensing, presented based on properties and usage of different nanomaterials spread across nine chapters. Content covers advances in nanomaterials, structural designing, and their scope in biomedical applications. Future developments of biosensing devices and related articulate methods are also described. Features: Gives a comprehensive view on the nanomaterials used in plasmonic optical fiber biosensors Includes synthesis, characterization, and usage for detection of different analytes Discusses trends in the design of wavelength-based optical fiber sensors Reviews micro- and nanostructured biosensing devices Explores application of plasmonic sensors in the biosensing field This book is aimed at researchers and graduate students in Optical Communications, Biomedical Engineering, Optics, Sensors, Instrumentation, and Measurement.
The book provides an introduction of surface plasmons and presents its applications in the sensing of various chemical and biological analyses using optical fiber technology. The field is developed by introducing the surface plasmons for semi-infinite metal-dielectric interface with discussion of their propagation length and penetration depth. Practical issues with the excitation of surface plasmons in different configurations and in various geometries including various means of their excitation have also been included. The book discusses the essential components of fiber optic sensors, their functions and the performance parameters along with the theoretical description of fiber optic Surface Plasmon Resonance (SPR) sensors with respect to various light launching conditions. The fabrication methods and protocols used for the fabrication of the fiber optic SPR chemical and biosensors have been described. Some fiber optic sensing applications based on SPR phenomena and various issues, such as sensitivity enhancement, influence of external stimuli etc, have been an important part of the book.The book will help beginners as well as established researchers in understanding the fundamentals and advancements of optical fiber plasmonic sensor technology. The book contains both the rigorous theory and the experimental techniques of SPR and related variety of sensors.
For the first time, distinguished scientists from key institutions worldwide provide a comprehensive approach to optical sensing techniques employing the phenomenon of guided wave propagation for chemical and biosensors. This includes both state-of the-art fundamentals and innovative applications of these techniques. The authors present a deep analysis of their particular subjects in a way to address the needs of novice researchers such as graduate students and post-doctoral scholars as well as of established researchers seeking new avenues. Researchers and practitioners who need a solid foundation or reference will find this work invaluable. This first of two volumes contains eight chapters covering planar waveguides for sensing, as well as sensing techniques based on plasmonic waveguides.
This book provides a thorough vision of the current trends in plasmonic optical fiber biochemical sensing. It gathers the most recent technological information and shows the maturity reached by the different subsequent technologies. Demonstrating roadmaps for the design process and implementation of plasmonic optical fiber biochemical sensors, the book bridges the gap between theory and application. With this philosophy, understanding key physical properties is of paramount importance for the efficient design of sensing platforms that will meet target specifications. You will learn about the role of the fiber configuration and the functional coating on the properties of the resulting optrodes. You will also get an encompassing overview on all optical fiber configurations used for plasmonic sensing thus far, especially on the progress made over the last decade and rendering the technology compatible for use in real conditions. The book presents both fundamental aspects and advanced applications while focusing on recent and emerging fields of research, such as the use of tilted fiber Bragg gratings, the integration of sensors in situ, the use of smart interrogation techniques, and much more. This is a unique reference for both beginners and experts in optical fiber-based sensors, especially for industrial engineers working in biophotonics and biochemical sensing, as it presents state-of-the-art design procedures and sensing features. The book’s theoretical background combined with recent advances of plasmonic-based optical fiber technologies also make it highly beneficial for all researchers, academics, and students specialized or interested in this flourishing and promising discipline.
Optical Biosensors, Second Edition describes the principles of successful systems, examples of applications, and evaluates the advantages and deficiencies of each. It also addresses future developments on two levels: possible improvements in existing systems and emerging technologies that could provide new capabilities in the future. The book is formatted for ease of use and is therefore suitable for scientists and engineers, students and researcher at all levels in the field. Comprehensive analysis and review of the underlying principles by optical biosensors Updates and informs on all the latest developments and hot topic areas Evaluates current methods showing the advantages and disadvantages of various systems involved
Plasmonic optical biosensors allow label-free and highly sensitive detection of analytes, usually within a dedicated microfluidic system that brings the sample to the biosensor surface. Since the nineties, an optical fiber counterpart to the bulky Kretschmann prism configuration implemented in most commercial systems is investigated and developed to allow in situ measurements with a miniaturized system. Thanks to straightforward light injection and considering the optical fiber geometry, such developments indeed allow remote operation in very small volumes of analytes of the order of 10 μL or even less. The plasmonic optical fiber technology is now mature to such a degree that it becomes to be industrialized. Various configurations comprising unclad/etched multimode optical fibers, D-shaped fibers, U-bent fibers, interferometers, and optical fiber gratings (tilted and long period fiber gratings) were reported. When combined with thin metal films or nanoparticles and functionalized with antibodies, aptamers or other relevant bioreceptors, they show unprecedented performance in terms of sensitivity and limit of detection. Also, the target applications are ever growing, covering biomedical sensing, environmental sensing, and food quality monitoring, among others. This will be a great resource for photonics Engineers and Bioengineers (Industrial engineers and researchers.
Plasmonics stems from the surface charge density oscillations at metal–dielectric interface, leading to extremely strong light–matter interactions. In the past few decades, plasmonics has become one of the most favorite fields/techniques in realizing high-performance photonic devices. For this purpose, different new concepts, such as exploration of different radiation frequency regions, two-dimensional materials/heterostructures, and different types of substrates for the excitation of plasmons have been investigated for plasmonics-based sensors and detectors. This book focuses on the recent and advanced works on optical sensors and detectors utilizing plasmonic techniques for opto-electronic applications. The book is unique as it describes both sensors and detectors based on plasmonics and their practical applications in a single book, a feature not found in any book so far.
Optical Biosensors: Present & Future
PART I. Optical Biosensors: The Present -- Chapter 1. Optrode-based Fiber Optic Biosensors -- Israel Biran and David R. Walt -- Chapter 2. Evanescent Wave Fiber Optic Biosensors -- Chris Rowe Taitt and Frances S. Ligler -- Chapter 3. Planar Waveguides for Fluorescence Biosensors -- Kim Sapsford, Chris Rowe Taitt, and Frances S. Ligler -- Chapter 4. Flow Immnosensor -- Anne W. Kusterbeck -- Chapter 5. Time Resolved Fluorescence -- Richard Thompson -- Chapter 6. Electrochemiluminescence -- Mark M. Richter -- Chapter 7. Surface Plasmon Resonance Biosensors -- Jiri Homola, Sinclair Yee, and David Myszka -- Chapter 8. The Resonant Mirror Optical Biosensor -- Tim Kinning and Paul Edwards -- Chapter 9. Interferometric Biosensors -- Daniel P. Campbell and Candice J. McCloskey -- Part II. Optical Biosensors: The Future -- Chapter 10. Genetic Engineering of Signaling Molecules -- Agatha Feltus and Sylvia Daunert -- Chapter 11. Artificial Receptors for Chemosensors -- Thomas W. Bell and Nicholas ...