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This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
The development of civilization entails the need to find new technological solutions leading to products with new properties. Allies in these efforts are microorganisms that have developed skills to synthesize products with properties of interest to the industry, environmental remediation or water treatment. The evolution of the omics approaches brought new tools to explore the microbial diversity and microorganisms' potential. These new methodological approaches are readily used in both industrial and environmental microbiology. This Special Issue collects research papers as well as review articles addressing recent advances on applied and environmental microbiology. The review articles critically discuss the importance of biopolymers, specifically xanthan gum, to improve soil properties and the importance that microorganisms of poorly explored environments, such as caves, may have in the production of new bioactive compounds. The microbiological aspects of wastewater treatment and occurrence of antibiotic resistance genes in wastewater and sludge are studied in two research papers. These works demonstrate the effect that treatment conditions may have in the modulation of the water bacterial communities and how treated wastewater may impact the receiving environment in terms of pollution with antibiotic resistance genes. Additionally, the influence that an invasive species (alligator weed) may have on wetlands organic matter accumulation and bacterial communities was studied, being demonstrated that the presence of the invasive weed affects the wetland microhabitat both in terms of organic matter content and bacterial communities structure.
This book has grown out of our shared experience in the development of the Stanford Synchrotron Radiation Laboratory (SSRL), based on the electron-positron storage ring SPEAR at the Stanford Linear Accelerator Center (SLAC) starting in Summer, 1973. The immense potential of the photon beam from SPEAR became obvious as soon as experiments using the beam started to run in May, 1974. The rapid growth of interest in using the beam since that time and the growth of other facilities using high-energy storage rings (see Chapters 1 and 3) demonstrates how the users of this source of radiation are finding applications in an increasingly wide variety of fields of science and technology. In assembling the list of authors for this book, we have tried to cover as many of the applications of synchrotron radiation, both realized already or in the process of realization, as we can. Inevitably, there are omissions both through lack of space and because many projects are at an early stage. We thank the authors for their efforts and cooperation in producing what we believe is the most comprehensive treatment of synchrotron radiation research to date.
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Integrals Related to the Error Function presents a table of integrals related to the error function, including indefinite and improper definite integrals. Most of the formulas in this book have not been presented in other tables of integrals or have been presented only for some special cases of parameters or for integration only along the real axis of the complex plane. Many of the integrals presented here cannot be obtained using a computer (except via an approximate numerical integration). Additionally, for improper integrals, this book emphasizes the necessary and sufficient conditions for the validity of the presented formulas, including trajectory for going to infinity on the complex plane; such conditions are usually not given in computer-assisted analytical integration and often not presented in the previously published tables of integrals. Features The first book in English language to present a comprehensive collection of integrals related to the error function Useful for researchers whose work involves the error function (e.g., via probability integrals in communication theory). Additionally, it can also be used by broader audience.