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Photoacoustics promises to revolutionize medical imaging and may well make as dramatic a contribution to modern medicine as the discovery of the x-ray itself once did. Combining electromagnetic and ultrasonic waves synergistically, photoacoustics can provide deep speckle-free imaging with high electromagnetic contrast at high ultrasonic resolution and without any health risk. While photoacoustic imaging is probably the fastest growing biomedical imaging technology, this book is the first comprehensive volume in this emerging field covering both the physics and the remarkable noninvasive applications that are changing diagnostic medicine. Bringing together the leading pioneers in this field to write about their own work, Photoacoustic Imaging and Spectroscopy is the first to provide a full account of the latest research and developing applications in the area of biomedical photoacoustics. Photoacoustics can provide functional sensing of physiological parameters such as the oxygen saturation of hemoglobin. It can also provide high-contrast functional imaging of angiogenesis and hypermetabolism in tumors in vivo. Discussing these remarkable noninvasive applications and so much more, this reference is essential reading for all researchers in medical imaging and those clinicians working at the cutting-edge of modern biotechnology to develop diagnostic techniques that can save many lives and just as importantly do no harm.
History of photoacoustics. Theory of pas of gases. Gas pas systems. Radiation sources. Photoacoustic spectroscopy of gases. Deexcitation studies in gases. Other gas pas experiments. General theory of the photoacoustic effect in condensed media: the gas-microphone signal. General theory of the photoacoustic effect in condensed media: the piezoelectric signal. Photoacoustic theory made easy. Photoacoustic spectrometers for condensed samples. Photoacoustic experiments with liquids. Spectroscopy studies. Chemical studies. Surface studies. Studies in biology. Studies in medicine. Deexcitation processes in condensed media. Thermal processes. Depht-profiling and tickness measurements. Experiments at low temperatures. Photoacoustic microscopy (PAM).
This book highlights the use of LEDs in biomedical photoacoustic imaging. In chapters written by key opinion leaders in the field, it covers a broad range of topics, including fundamentals, principles, instrumentation, image reconstruction and data/image processing methods, preclinical and clinical applications of LED-based photoacoustic imaging. Apart from preclinical imaging studies and early clinical pilot studies using LED-based photoacoustics, the book includes a chapter exploring the opportunities and challenges of clinical translation from an industry perspective. Given its scope, the book will appeal to scientists and engineers in academia and industry, as well as medical experts interested in the clinical applications of photoacoustic imaging.
Summarizes the current status of photoacoustic (PA) infrared spectroscopy so that chemical analysts and researchers can determine whether the method is appropriate for their needs. Michaelian (National Resources Canada) describes a series of seven experimental PA methods that have employed by researchers during the last two decades, characterizes depth profiling techniques, and outlines three numerical methods that pertain to PA spectroscopy. Following is the largest chapter, which overviews 15 applications of PA infrared spectroscopy to different sample materials, such as carbons, clay, wood, polymers, and textiles. An appendix cites 543 articles on PA published since 1978, along with their sample type. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com).
Optoacoustic Spectroscopy and Detection discusses the fundamental principles and practice of optoacoustic spectroscopy. This book serves as a basis for evaluation of the feasibility of using such techniques in specific instances. Organized into eight chapters, this book starts with an overview of the detection and identification of gas contaminants, which is necessary to understand the physical description of the generation and measurement of the optoacoustic signal. This text then provides an understanding of the optoacoustic effect on a molecular scale and describes the energy transfer processes and estimates of the lifetimes of vibrationally excited states. Other chapters consider the options available to the researcher in the selection of optoacoustic system design. This book discusses as well the capabilities and limitations of various optoacoustic system designs. The final chapter deals with the technique used for exploring the absorption spectra of substances, including powders, gels, adsorbed films, and organic tissues. This book is a valuable resource for researchers and graduate students engaged in the study of optoacoustic spectroscopy.
This invaluable and up-to-date source on instruments and applications covers everything needed to employ a technique for investigating various gases and materials, including biomaterials. It includes the latest developments in light sources, signal recovery and numerical methods. There is no other single publication that reviews the entire subject of photoacoustic infrared spectroscopy in such detail. Physicists, chemists, and spectroscopists in both academic and industrial laboratories, polymer and organic chemists, analysts in industry, forensic and government laboratories, and materials scientists will find this book to be a vital resource.
Gas-phase photoacoustics are treated comprehensively for the first time in this book. Review articles by leading scientists in the respective research areas introduce their fields, review present knowledge and conclude with the latest developments and future prospects. Topics covered include the theory of photoacoustics in the frequency and time domains, acoustic resonator models, a great variety of experimental setups and techniques, studies of spectrocopy and fundamental kinetic processes such as energy transfer and chemical reactions, and applications such as air and exhaust monitoring and trace gas detection in biology and agriculture. The book will interest newcomers to photoacoustics, since it gives an overview of the important directions of current research and detailed descriptions of experimental methods. It will also be a valuable source of information for those already involved in photoacoustic research due to its clear presentation of theory and experimental results. All relevant literature references in this rapidly expanding field of laser applications are included.
Photoacoustic imaging (PAI) is an emerging non-invasive imaging modality that integrates the advantages of deep ultrasound penetration and high optical contrast. It provides better resolution than pure ultrasonic imaging and deeper penetration than pure optical imaging. Hence, it is opening new frontiers in diagnostic imaging. Photoacoustic Imaging - Principles, Advances and Applications, provides interested readers with the principle knowledge, advanced methodologies, and new applications associated with PAI technology. Written by expert researchers, chapters cover such topics as the generation and detection of photoacoustic signals, sound source localization, image reconstruction and formation, and application of PAI in gastroenterology and ophthalmology.
This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas
The concept of photoacoustic tomography (PAT) emerged in the mid-1990s, and the field of PAT is now rapidly moving forward. Presenting the research of a well-respected pioneer and leading expert, Photoacoustic Tomography is a first-of-its-kind book covering the underlying principles and practical applications of PAT in a systematic manner. Written in a tutorial format, the text: Addresses the fundamentals of PAT, the theory on photoacoustic effect, image reconstruction methods, and instrumentation Details advanced methods for quantitative PAT, which allow the recovery of tissue optical absorption coefficient and/or acoustic properties Explores the development of several image-enhancing schemes, including both software and hardware approaches Examines array-based PAT systems that are the foundation for the realization of 2-D, 3-D, and 4-D PAT Discusses photoacoustic microscopy (PAM) and combinations of PAT/PAM with other imaging methods Considers contrast-agents-based molecular PAT, with both nontargeted and cell receptor–targeted methods Describes clinical applications and animal studies in breast cancer detection, osteoarthritis diagnosis, seizure localization, intravascular imaging, and image-guided cancer therapy Photoacoustic Tomography is an essential reference for graduate students, researchers, industry professionals, and those who wish to enter this exciting field.