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The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis. - Fully revised to cover new and emerging topics - Provides an important bridge between broad-based biochemistry research and application - Presents key concepts that are supported by figures and models to improve understanding - Includes references from current literature in each chapter to facilitate in-depth study
Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.
Challenges and Innovations in Ocean In-Situ Sensors: Measuring Inner Ocean Processes and Health in the Digital Age highlights collaborations of industry and academia in identifying the key challenges and solutions related to ocean observations. A new generation of sensors is presented that addresses the need for higher reliability (e.g. against biofouling), better integration on platforms in terms of size and communication, and data flow across domains (in-situ, space, etc.). Several developments are showcased using a broad diversity of measuring techniques and technologies. Chapters address different sensors and approaches for measurements, including applications, quality monitoring and initiatives that will guide the need for monitoring. - Integrates information across key marine and maritime sectors and supports regional policy requirements on monitoring programs - Offers tactics for enabling early detection and more effective monitoring of the marine environment and implementation of appropriate management actions - Presents new technologies driving the next generation of sensors, allowing readers to understand new capabilities for monitoring and opportunities for another generation of sensors - Includes a global vision for ocean monitoring that fosters a new perspective on the direction of ocean measurements
New Methods and Sensors for Membrane and Cell Volume Research, Volume 88 provides an overview of novel experimental approaches to study both the cell membrane and the under-membrane space – the cytosol, which have lately began drawing renewed attention. The book's overall emphasis is on fluorescent and FRET-based sensors, however, other optical (such as variants of transmission microscopy) and non-optical methods (neutron scattering and mass spectrometry) also have dedicated chapters. This volume provides a rare review of experimental approaches to study intracellular phase transitions, as well as anion channels, membrane tension and dynamics, and other topics of intense current interest. - Describes novel FRET-based membrane sensors - Reviews selected non-optical approaches to membrane structure and dynamics - Describes traditional and modern aspects of cell volume research, such as phase transitions and macromolecular crowding
This ECS Transactions issue is a compilation of papers presented at the PRiME 2008 Joint International Meeting, held in Hawaii from October 12 - October 17, 2008. The papers presented covered the research and development in the field of chemical (gas, ion, bio and other) sensors, including molecular recognition surface, transduction methods, and integrated and micro sensor systems.
Ferritins—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Ferritins in a compact format. The editors have built Ferritins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ferritins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Ferritins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Over time, the increased use of fresh water for agriculture and industry together with contamination from discharges of pollutants, mean that ever more areas of the planet are becoming water-stressed. Because of the competing needs of communities and industry for fresh water, industry will be challenged to meet its growing demands for water, which is essential for producing the goods and services that would boost human welfare. Thus industry will need to learn how to cost-effectively purify and recycle its wastewater for reuse, ultimately approaching a net zero-discharge condition. The chapters in this book, written by international experts, treat the technical issues of such treatment and water management, and also provide guidance on technologies, either existing or in development, that can potentially achieve the goal of recycle-reuse. The book will serve as a useful reference for academics, government and industry professionals alike.
This book arises from the NATO Advanced Study Institute “Technological Innovations in Detection and Sensing of CBRN Agents and Ecological Terrorism” held in Chisinau, Republic of Moldova in June 2010. It comprises a variety of invited contributions by highly experienced educators, scientists, and industrialists, and is structured to cover important aspects of the field that include developments in chemical-biological, and radiation sensing, synthesis and processing of sensors, and applications of sensors in detecting/monitoring contaminants introduced/dispersed inadvertently or intentionally in air, water, and food supplies. The book emphasizes nanomaterials and nanotechnology based sensing and also includes a section on sensing and detection technologies that can be applied to information security. Finally, it examines regional, national, and international policies and ethics related to nanomaterials and sensing. It will be of considerable interest and value to those already pursuing or considering careers in the field of nanostructured materials and nanotechnology based sensing, In general, it serves as a valuable source of information for those interested in how nanomaterials and nanotechnologies are advancing the field of sensing, detection, and remediation, policy makers, and commanders in the field.