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The historical approach to the interpretation of physical, chemical and biological phenomena has been to consider relationships with causative factors that can be reduced to linearity allowing simple and direct interpretation. However, it is increasingly evident that there is often more information in the data than linear interpretations allow. The current capacity for computers to assist in identifying non-linear relationships allows greater interpretation of data which illuminates the phenomena allowing the information to be translated into knowledge that can be used wisely to promote various desirable pharmaceutical outcomes. This short volume is intended to stimulate the reader to contemplate research and development areas in which the data might be more accurately interpreted to allow greater understanding and ultimately control of the pharmaceutically complex phenomena.
Non-linear phenomena pervade the pharmaceutical sciences. Understanding the interface between each of these phenomena and the way in which they contribute to overarching processes such as pharmaceutical product development may ultimately result in more efficient, less costly and rapid implementation. The benefit to Society is self-evident in that affordable treatments would be rapidly forthcoming. We have aggregated these phenomena into one topic “Pharmaco-complexity: Non-linear Phenomena and Drug Product Development”.
A significant amount of complexity exists within the brand and product portfolios of PharmaCo. This complexity is driven by several factors: first, medical needs for differing products and dosages; second, marketing requests for new configurations of current product offerings; third, unique regulations and requirements for individual country markets; fourth, product portfolio growth from acquisition activity. This complexity increases both production costs and support costs (such as planning and procurement) for PharmaCo. The focus of this project is to reduce the complexity in the brand and SKU portfolios at PharmaCo. Two approaches can be utilized to reduce complexity in the product portfolio. First, measures can be taken to reduce already existing SKUs and brands. This has largely been the focus of previous efforts at PharmaCo, although additional work remains in this area. Previous analyses have focused on providing recommendations for pruning specific SKUs and divesting or pruning specific brands. Second, measures can be taken to manage the future proliferation of SKUs and brands in order to control future complexity growth. This approach has been largely unaddressed in previous internship projects and will be a major focus of the current project. It is first necessary to clearly understand all costs that are associated with complexity. Consequently, the first step of this project was to conduct site visits with multiple plants in order to learn all costs that are impacted by complexity. At these site visits, cross functional groups involved in all aspects of operations at the site were identified and consulted. Additionally, Marketing was contacted to understand complexity costs that affect Marketing. Both cost elements will be combined to develop a complexity cost model. This model is being piloted and applied to a stable brand that still has level or increasing volumes over the next several years.
Complexity is slowing companies down, costing them on average 10% of their profits. Based on cutting-edge research, this practical 'how to' guide will show businesses how to remove complexity to boost profits and morale.
Increasingly, pharmaceuticals are available as the solutions to a wide range of human health problems and health risks, minor and major. This book portrays how pharmaceutical use is, at once, a solution to, and a difficulty for, everyday life. Exploring lived experiences of people at different stages of the life course and from different countries around the world, this collection highlights the benefits as well as the challenges of using medicines on an everyday basis. It raises questions about the expectations associated with the use of medications, the uncertainty about a condition or about the duration of a medicine regimen for it, the need to negotiate the stigma associated with a condition or a type of medicine, the need to access and pay for medicines and the need to schedule medicine use appropriately, and the need to manage medicines’ effects and side effects. The chapters include original empirical research, literature review and theoretical analysis, and convey the sociological and phenomenological complexity of ‘living pharmaceutical lives’. This book is of interest to all those studying and researching social pharmacy and the sociology of health and illness.
As the scope of available drug therapies expands, spending on prescription drugs has become the fastest-growing category of total spending on health care in the United States. Recently, that growth has slowed and that slowdown reflects changes in both the supply and demand for prescription drugs. This book examines the innovation, development and complexity issues present in the pharmaceutical industry.
Vols. for 1912-45 include proceedings of the association's annual meeting.
Registered Nurses must have thorough knowledge of pharmacology, medicines administration, and the effects of medicines. Fundamentals of Pharmacology for Children's Nurses is written for nurses and allied health professionals involved in the care of children and young people (CYP) to focus exclusively on pharmacology. Filling a gap in current literature on the subject, this much-needed resource develops the competence and confidence required to prescribe, dispense, and administer medicines to children and young people. Emphasising the importance of patient-centered care to CYP, the text describes the role of the healthcare provider working with CYP and their families; explains how to use pharmaceutical and prescribing reference guides; discusses legal and ethical issues; examines pharmacodynamics and pharmacokinetics, and more. Helping readers respond appropriately and compassionately to the needs of those receiving care and their families, this textbook: Covers a wide range of medications used in diabetes, cancer, mental health, and other areas Features a wealth of full-colour images and numerous pedagogical tools including learning objectives, self-test questions, and reflective exercises to enable readers to contextualise and assess their knowledge Presents case studies to reinforce learning, and illustrate the application of theory to practice Provides authoritative and practical guidance on formulations, adverse drug reactions, analgesics, antibiotics, immunisations, and the medications most commonly used when providing care to CYP Includes access to a companion website with interactive MCQs, case studies, references, an image bank, and links to further reading and supplemental resources Fundamentals of Pharmacology for Children's Nurses is essential reading for undergraduate children's nursing students, trainee nursing associates, those undertaking healthcare programmes of study, as well as those seeking to better understand pharmacology.
This book provides comprehensive information about simulation in pharmacy education, practice and research. It serves as a source for guiding pharmacy academics, clinicians, researchers, supervisors, trainers, and students who wish to learn more about and introduce simulation in pharmacy education, practice and research. Furthermore, this book describes the current practice, the facilitators and barriers for implementing evidence-based simulation, and provides examples from real simulation practice in education, practice and research. Structured into three sections, the first delves into the different types of simulation and their applications within pharmacy curricula. From patient simulation to computer-based programs, this section highlights the diverse opportunities for experiential learning in pharmacy education. The next discusses the role of simulation in community and hospital pharmacy settings. This section emphasizes the importance of communication skills, patient care, and medication safety, demonstrating how simulation can contribute to improved practice and patient outcomes. The last section explores the use of simulation in drug development and research design. This section also examines the ethical considerations, data analysis, and reporting involved in simulation-based research. Comprehensive and practical, Comprehensive Healthcare Simulation: Pharmacy Education, Practice and Research is an essential resource for anyone interested in the expanding field of pharmacy simulation.